(8R,9S,10S,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (8R,9S,10S,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
• 化学式: C₂₁H₃₂O₄
• 分子量: 348.5
• InChiKey: WNIBSYGPDJBVOA-KBPDBWGHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• ASSAY FOR ANALYTES USING MULTIPLE RECEPTORS
  申请人：Lewisch Sandra A.

  公开号：US20120045847A1

  公开（公告）日：2012-02-23

  A method for determining an analyte in a sample suspected of containing the analyte comprises providing in combination a medium, the sample, and two or more different receptors. Each different receptor binds to at least two different epitopic sites. One of the epitopic sites is a common binding site and one of the epitopic sites is non-common binding site. The non-common epitopic sites are different for each different receptor. The receptors exhibit mono-molecular binding. The medium is incubated under conditions for binding of the receptors to the epitopic sites. The medium is examined for the presence and/or amount of complexes comprising the epitopic sites and the receptors. The presence and/or amount of the complexes indicate the presence and/or amount of the analyte in the sample.

  一种用于测定样品中可能含有的分析物的方法，包括将介质、样品和两个或更多不同的受体组合在一起。每个不同的受体结合至少两个不同的表位。其中一个表位是共同的结合位点，另一个表位是非共同的结合位点。非共同表位对于每个不同的受体是不同的。受体表现出单分子结合。在结合受体到表位的条件下，孵育介质。检查介质中是否存在并/或复合物的数量，包括表位和受体。复合物的存在和/或数量表明样品中存在和/或分析物的数量。
• Assay for analytes using multiple receptors
  申请人：Lewisch Sandra A.

  公开号：US10088490B2

  公开（公告）日：2018-10-02

  A method for determining an analyte in a sample suspected of containing the analyte comprises providing in combination a medium, the sample, and two or more different receptors. Each different receptor binds to at least two different epitopic sites. One of the epitopic sites is a common binding site and one of the epitopic sites is non-common binding site. The non-common epitopic sites are different for each different receptor. The receptors exhibit mono-molecular binding. The medium is incubated under conditions for binding of the receptors to the epitopic sites. The medium is examined for the presence and/or amount of complexes comprising the epitopic sites and the receptors. The presence and/or amount of the complexes indicate the presence and/or amount of the analyte in the sample.

  一种用于确定疑似含有分析物的样品中分析物的方法，包括结合提供介质、样品和两种或两种以上不同的受体。每个不同的受体至少与两个不同的表位结合。其中一个表位是普通结合位点，另一个表位是非普通结合位点。每个不同受体的非共用表位点都不同。受体呈现单分子结合。培养基在受体与表位结合的条件下进行培养。检测培养基中是否存在由表位点和受体组成的复合物和/或复合物量。复合物的存在和/或数量表明样品中分析物的存在和/或数量。
• ASSAY FOR DETECTION OF ADRENAL TUMOUR
  申请人：The University of Birmingham

  公开号：EP2396658B1

  公开（公告）日：2015-12-16
• BIOMARKERS
  申请人：Oxford University Innovation Limited

  公开号：EP4097487A1

  公开（公告）日：2022-12-07
• US4945089A
  申请人：——

  公开号：US4945089A

  公开（公告）日：1990-07-31