O-(3,5,6-trichloropyridin-2-yl) O,O-dihydrogenphosphorothioate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫代磷酸及其衍生物
• 英文名称: O-(3,5,6-trichloropyridin-2-yl) O,O-dihydrogenphosphorothioate
• 英文别名: O-3,5,6-trichloro-2-pyridyl phosphorothioate；O-(3,5,6-trichloro-2-pyridinyl) phosphorothioic acid；dihydroxy-sulfanylidene-(3,5,6-trichloropyridin-2-yl)oxy-λ5-phosphane
• 化学式: C₅H₃Cl₃NO₃PS
• 分子量: 294.482
• InChiKey: HRTHBRJHONAZLY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  94.7
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  甲基毒死蜱 在 CuCl₂*2H₂O 作用下， 以 甲醇 、 水 为溶剂， 生成 Thiophosphoric acid O-methyl ester O'-(3,5,6-trichloro-pyridin-2-yl) ester 、 O-(3,5,6-trichloropyridin-2-yl) O,O-dihydrogenphosphorothioate
  参考文献：
  名称：

  Divalent Metal Ion-Catalyzed Hydrolysis of Phosphorothionate Ester Pesticides and Their Corresponding Oxonates

  摘要：

  The divalent metal ion-catalyzed hydrolysis of thionate (P=S) and oxonate (P=O) organophosphorus pesticides has been examined in light of three possible catalysis mechanisms: (1) metal ion coordination of the thionate sulfur or oxonate oxygen to enhance the electrophilicity of the phosphorus electrophilic site; (2) metal ion coordination and induced deprotonation of water to create a reactive nucleophile; and (3) metal ion coordination of the leaving group to facilitate its exit. The effect of the following metals at a concentration of 1 mM was examined: COII, Ni-II, Cu-II, Zn-II and Pb-II. These metal ions were chosen for their ability to complex organic ligands and inorganic nucleophiles. Of these metal ions, Cu-II possesses properties most suitable for all three catalytic mechanisms and serves as the most effective catalyst for the five thionate esters (chlorpyrifos-methyl, zinophos, diazinon, parathion-methyi, and ronnel) and the two oxonate esters (chlorpyrifos-methyl oxon and paraoxon) included in this study. A decrease in the degree of Cu-II catalysis at high pH arises from solubility limitations. Pb-II nearly matches Cu-II as a catalyst for oxonate esters, but is a less effective catalyst for thionate esters. Catalysis by Co-II, Ni-II, and Zn-II is negligible. Phenolate product analysis indicates that metal catalysis in some instances shifts hydrolysis from alkyl carbon-centered pathways to phosphorus-centered pathways.

  DOI：

  10.1021/es960499q

文献信息

• Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof
  申请人：——

  公开号：US20030119670A1

  公开（公告）日：2003-06-26

  A triazolone compound of the formula [I]: 1 wherein; R 1 represents optionally substituted phenyl or the like, T represents m-phenylene optionally substituted by methyl or the like; and a fungicidal composition containing it as an active ingredient.

  一种三唑酮化合物，化学式为[I]：1其中；R1代表可选择地取代的苯基或类似物，T代表m-苯亚甲基，可选择地取代为甲基或类似物；以及一种含有该化合物作为活性成分的杀真菌组合物。
• Amidine compounds and their use as pesticides
  申请人：——

  公开号：US20010041740A1

  公开（公告）日：2001-11-15

  The present invention provides novel amidine compounds and novel pesticides containing these amidine compounds as active ingredients. The amidine compounds are expressed by formula I: 1 wherein X and Y are the same or different and are independently halogen, nitro, cyano, or C 1 -C 6 alkyl; Z is C 1 -C 6 haloalkyl or C 1 -C 6 haloalkoxy; R 1 is hydrogen, halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, or a group of formula: S(O) n —R 5 (wherein R 5 is C 1 -C 6 alkyl or C 1 -C 6 haloalkyl; and n is 0, 1, or 2); R 2 and R 3 are the same or different and are independently halogen or C 1 -C 6 haloalkyl; and R 4 is a group of formula: NR 6 R 7 or N═CR 8 R 9 (wherein R 6 is hydrogen, C 1 -C 6 alkyl, (C 1 -C 6 alkoxy)-carbonyl, (C 1 -C 6 alkoxy) C 1 -C 6 alkyl, or C 2 -C 6 acyl; R 7 is hydrogen, C 1 -C 6 alkyl, (C 1 -C 6 alkoxy)carbonyl, or C 2 -C 6 acyl; R 8 is C 1 -C 6 alkyl or hydrogen; and R 9 is C 1 -C 6 alkoxy, C 1 -C 6 alkyl, or di(C 1 -C 6 alkyl)amino).

  本发明提供了新型胺基化合物和含有这些胺基化合物作为活性成分的新型杀虫剂。这些胺基化合物由式I表示：其中X和Y相同或不同，独立地是卤素、硝基、氰基或C1-C6烷基；Z是C1-C6卤代烷基或C1-C6卤代氧烷基；R1是氢、卤素、C1-C6烷基、C1-C6卤代烷基、C1-C6烷氧基、C1-C6卤代烷氧基，或者是一个由下式表示的基团：S(O)n—R5（其中R5是C1-C6烷基或C1-C6卤代烷基；n为0、1或2）；R2和R3相同或不同，独立地是卤素或C1-C6卤代烷基；R4是一个由下式表示的基团：NR6R7或N═CR8R9（其中R6是氢、C1-C6烷基、（C1-C6烷氧基）-羰基、（C1-C6烷氧基）C1-C6烷基或C2-C6酰基；R7是氢、C1-C6烷基、（C1-C6烷氧基）羰基或C2-C6酰基；R8是C1-C6烷基或氢；R9是C1-C6烷氧基、C1-C6烷基或二(C1-C6烷基)氨基）。
• Amide compounds and use thereof
  申请人：——

  公开号：US20030195354A1

  公开（公告）日：2003-10-16

  An amide compound given by formula [I]: 1 wherein R 1 represents a C1-C10 haloalkyl and so on, R2 represents a hydrogen and so on, X represents an oxygen or sulfur, Y represents an oxygen or sulfur, Ar represents an aromatic group, A represents an ethylene and so on, and Z 1 and Z 2 represent alkyl, alkoxy and so on, and a fungicide containing it as an active ingredient.

  由公式[I]给出的酰胺化合物，其中R1代表C1-C10卤代烷基等，R2代表氢等，X代表氧或硫，Y代表氧或硫，Ar代表芳香族基团，A代表乙烯等，Z1和Z2代表烷基、烷氧基等，以及一种含有它作为活性成分的杀真菌剂。
• Ester Compounds, methods of controlling a pest and uses of the ester compounds
  申请人：——

  公开号：US20020169329A1

  公开（公告）日：2002-11-14

  The present invention provides ester compounds, methods of controlling a pest and uses of the ester compounds. The ester compounds are encompassed by formula (1): 1 wherein R represents a C1 to C3 alkyl group. The methods of controlling a pest entail applying the ester compound encompassed by formula (1) to a pest or to a habitat of the pest or both. The uses of the ester compounds encompassed by formula (1) are for controlling pests.

  本发明提供酯化合物，用于控制害虫的方法以及酯化合物的用途。酯化合物由式(1)包围：其中R代表C1至C3烷基。控制害虫的方法包括将由式(1)包围的酯化合物应用于害虫或害虫栖息地或两者。由式(1)包围的酯化合物的用途是用于控制害虫。
• SYNERGISTIC PESTICIDAL COMPOSITIONS AND RELATED METHODS
  申请人：Dow AgroSciences LLC

  公开号：US20150111738A1

  公开（公告）日：2015-04-23

  A pesticidal composition comprises a synergistically effective amount of an organophosphate-based acetylcholinesterase (AChE) inhibitor compound and a pesticide selected from N-(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-N-ethyl-3-((3,3,3-trifluoropropyl)thio)propanamide (I), N-(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-N-ethyl-3-((3,3,3-trifluoropropyl)sulfinyl)propanamide (II), or any agriculturally acceptable salt thereof. A method of controlling pests comprises applying the pesticidal composition near a population of pests. A method of protecting a plant from infestation and attack by insects comprises contacting the plant with the synergistic pesticidal composition.

  一种杀虫组合物包括一种有机磷基乙酰胆碱酯酶（AChE）抑制剂化合物的协同有效量和从N-（3-氯-1-（吡啶-3-基）-1H-吡唑-4-基）-N-乙基-3-（（3,3,3-三氟丙基）硫）丙酰胺（I），N-（3-氯-1-（吡啶-3-基）-1H-吡唑-4-基）-N-乙基-3-（（3,3,3-三氟丙基）亚砜）丙酰胺（II）或其任何农业可接受的盐中选择的杀虫剂。一种控制害虫的方法包括在害虫种群附近应用杀虫组合物。一种保护植物免受昆虫侵害和攻击的方法包括将植物与协同杀虫组合物接触。