(1R,2R)-N,N'-bis(pentafluorobenzenesulfonyl)-1,2-diphenylethylenediamine

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (1R,2R)-N,N'-bis(pentafluorobenzenesulfonyl)-1,2-diphenylethylenediamine
• 英文别名: 2,3,4,5,6-pentafluoro-N-[(1R,2R)-2-[(2,3,4,5,6-pentafluorophenyl)sulfonylamino]-1,2-diphenylethyl]benzenesulfonamide
• 化学式: C₂₆H₁₄F₁₀N₂O₄S₂
• 分子量: 672.524
• InChiKey: WZYIWXFGISQHFV-DNQXCXABSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  44
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  109
• 氢给体数：
  2
• 氢受体数：
  16

反应信息

• 作为产物：
  描述：

  2,3,4,5,6-五氟苯磺酰氯 、 (1R,2R)-1,2-二苯基乙二胺 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 7.0h， 以98%的产率得到(1R,2R)-N,N'-bis(pentafluorobenzenesulfonyl)-1,2-diphenylethylenediamine
  参考文献：
  名称：

  Enantioselective radical-mediated allylation of α-iododihydrocoumarins using Lewis acids generated from chiral sulfonamides

  摘要：

  Enantioseletive radical-mediated allylation using chiral Lewis acids generated from sulfonamides is described. Asymmetric allylation took place in 54% enantiomeric excess to form a chiral quaternary carbon center with R configuration. The present reaction proceeded equally well with a substoichiometric amount of a chiral Lewis acid as with a stoichiometric amount. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(98)00212-2

文献信息

• Enantioselective radical-mediated allylation of α-iododihydrocoumarins using Lewis acids generated from chiral sulfonamides
  作者：Masatoshi Murakata、Toshiaki Jono、Osamu Hoshino

  DOI：10.1016/s0957-4166(98)00212-2

  日期：1998.6

  Enantioseletive radical-mediated allylation using chiral Lewis acids generated from sulfonamides is described. Asymmetric allylation took place in 54% enantiomeric excess to form a chiral quaternary carbon center with R configuration. The present reaction proceeded equally well with a substoichiometric amount of a chiral Lewis acid as with a stoichiometric amount. (C) 1998 Elsevier Science Ltd. All rights reserved.