S-phthalazin-1-yl ethanethioate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: S-phthalazin-1-yl ethanethioate
• 化学式: C₁₀H₈N₂OS
• 分子量: 204.25
• InChiKey: CQIFQWGJTMTJBT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  68.2
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• 1, 3-DIAMINO-2-HYDROXYPROPANE PRODRUG DERIVATIVES
  申请人：Elan Pharmaceuticals, Inc.

  公开号：EP1534693A2

  公开（公告）日：2005-06-01
• [EN] 1, 3-DIAMINO-2-HYDROXYPROPANE PRODRUG DERIVATIVES<br/>[FR] DERIVES DE PROMEDICAMENTS A BASE DE 1, 3-DIAMINO-2-HYDROXYPROPANE
  申请人：ELAN PHARM INC

  公开号：WO2004022523A2

  公开（公告）日：2004-03-18

  The present invention relates to compounds of formula (AA), (I) and (X), useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.