2-Chlorpentylamin

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 英文名称: 2-Chlorpentylamin
• 英文别名: 2-Chloropentan-1-amine
• 化学式: C₅H₁₂ClN
• 分子量: 121.61
• InChiKey: ZYODVPIAACPQPF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  7
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  Diethyl-chlor-(2-chlor-n-pentyl)-phosphoramidat 在 盐酸 、 sodium hydrogensulfite 作用下， 以 正己烷 、 苯 为溶剂， 生成 2-Chlorpentylamin
  参考文献：
  名称：

  Pinchuk,A.M. et al., Journal of general chemistry of the USSR, 1975, vol. 45, p. 1219 - 1225

  摘要：

  DOI：

文献信息

• Process for producing amino group terminated polyphenylene ether
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：EP0476619A2

  公开（公告）日：1992-03-25

  A process for producing an amino group terminated polyphenylene ether represented by the following general formula (I) wherein Q1s each represents a halogen atom, a primary or secondary alkyl group, a phenyl group, an aminoalkyl group, a hydrocarbon oxy group or a halohydrocarbon oxy group; Q2s each represents a hydrogen atom, a halogen atom, a primary or secondary alkyl group, a phenyl group, a haloalkyl group, a hydrocarbon oxy group or halohydrocarbon oxy group; R represents an aliphatic hydrocarbon group having 1 to 32 carbon atoms, an aromatic hydrocarbon group or an araliphatic hydrocarbon group; and n is a number of 10 to 500, which process comprises reacting a polyphenylene ether represented by the following general formula (II) wherein Q1, Q2 and n are as define above, with a primary amine halide represented by the following general formula (III) wherein R is as defined above, and X represents a halogen atom. There are also disclosed a resin composition comprising an amino group-terminated polyphenylene ether of general formula (I) and a functionalized olefin resin selected from a carboxyl group containing olefin resin and an epoxy group containing olefin resin, and a resin composition comprising an amino group terminated polyphenylene ether of general formula (I) and a polyamide or a thermoplastic polyester.

  一种生产由以下通式(I)代表的氨基封端聚苯醚的工艺 其中 Q1s 分别代表卤素原子、伯或仲烷基、苯基、氨基烷基、烃氧基或卤代烃氧基； Q2s 分别代表氢原子、卤素原子、伯或仲烷基、苯基、卤代烷基、烃氧基或卤代烃氧基；R 代表具有 1 至 32 个碳原子的脂肪族烃基、芳香族烃基或芳香族烃基；以及 n 是 10 至 500 之间的数字，该工艺包括使以下通式 (II) 所代表的聚苯醚发生反应 其中 Q1、Q2 和 n 如上定义，与下式通式（III）代表的伯胺卤化物反应 其中 R 如上定义，X 代表卤素原子。 还公开了一种树脂组合物，它包括通式（I）的氨基封端聚苯醚和一种官能化烯烃树脂，该烯烃树脂选自含羧基的烯烃树脂和含环氧基的烯烃树脂；还公开了一种树脂组合物，它包括通式（I）的氨基封端聚苯醚和一种聚酰胺或热塑性聚酯。
• US5191030A
  申请人：——

  公开号：US5191030A

  公开（公告）日：1993-03-02
• [EN] PRODRUGS OF DRUG-PHOSPHATE CONJUGATES AND ANALOGS THEREOF<br/>[FR] PROMEDICAMENTS CONTENANT DES CONJUGUES DE PHOSPHATE-MEDICAMENT ET DES ANALOGUES DE CEUX-CI
  申请人：PURDUE RESEARCH FOUNDATION

  公开号：WO2006037090A2

  公开（公告）日：2006-04-06

  Phosphate-substituted therapeutic compounds and analogs thereof that may serve as prodrugs are described. The prodrugs may include phosphorus-containing compounds, drug-phosphate conjugates, and analogs of drug-phosphate conjugates. Also described are analogs of drugs, including phosphorylated drugs, where the linker connecting the phosphate fragment to the drug fragment is other than oxygen, such as but not limited to linkers forming phosphoramidates, phosphonates, difluorophosphonates, oxophosphonates, and the like.
• [EN] PRODRUGS AND CONJUGATES OF PRENYLATION INHIBITORS<br/>[FR] PROMEDICAMENTS ET CONJUGUES D'INHIBITEURS DE PRENYLATION
  申请人：PURDUE RESEARCH FOUNDATION

  公开号：WO2006099313A2

  公开（公告）日：2006-09-21

  [EN] Described herein are neutral prodrugs of phosphorus-containing inhibitors of farnesyl transferase that include one or more phosphate fragments or analogs of phosphate fragments. Analogs of phosphate fragments include various linkers other than oxygen connecting the phosphate fragment to the remaining portion of the drug, such as but not limited to linkers forming phosphoramidates, phosphonates, difluorophosphonates, phosphordiamidates, and the like.
  [FR] L'invention concerne des promédicaments neutres d'inhibiteurs contenant du phosphore de farnésyl transférase qui comprennent un ou plusieurs fragments de phosphate ou analogues de fragments de phosphate. Les analogues de fragments de phosphate comprennent divers lieurs autres que l'oxygène reliant le fragment de phosphate à la partie restante du médicament, tels que, entre autres, les lieurs formant des phosphoramidates, phosphonates, difluorophosphonates, phosphordiamidates, et analogues.
• Pinchuk,A.M. et al., Journal of general chemistry of the USSR, 1975, vol. 45, p. 1219 - 1225
  作者：Pinchuk,A.M. et al.

  DOI：——

  日期：——