1,2-dimethoxy-1-phenyltetralin

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: 1,2-dimethoxy-1-phenyltetralin
• 英文别名: 3,4-dimethoxy-4-phenyl-2,3-dihydro-1H-naphthalene
• 化学式: C₁₈H₂₀O₂
• 分子量: 268.356
• InChiKey: SKEGSSDHTMJUBD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  甲醇 、 3,4-二氢-1-苯基萘 在 ammonium cerium(IV) nitrate 作用下， 反应 1.0h， 以65%的产率得到1,2-dimethoxy-1-phenyltetralin
  参考文献：
  名称：

  Oxidative fragmentation of 1-aryl-1-cycloalkenes using cerium(IV) ammonium nitrate (CAN): some novel observations

  摘要：

  1-Phenyl-1-cycloalkenes undergo oxidative fragmentation in presence of CAN in methanol, affording 1,n-dicarbonyl compounds as the major products along with 1,2-dimethoxycycloalkanes. The reaction under deoxygenated conditions afforded the latter in good yields. In the presence of azide ion, fragmentation leading to the corresponding cyanoketones was observed whereas with sultinate only the 1-methoxy-2-sulfonyl cycloalkanes were formed. (C) 2002 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(02)00261-2

文献信息

• Oxidative fragmentation of 1-aryl-1-cycloalkenes using cerium(IV) ammonium nitrate (CAN): some novel observations
  作者：Vijay Nair、Sreeletha B Panicker、Siji Thomas、V Santhi、Sindhu Mathai

  DOI：10.1016/s0040-4020(02)00261-2

  日期：2002.4

  1-Phenyl-1-cycloalkenes undergo oxidative fragmentation in presence of CAN in methanol, affording 1,n-dicarbonyl compounds as the major products along with 1,2-dimethoxycycloalkanes. The reaction under deoxygenated conditions afforded the latter in good yields. In the presence of azide ion, fragmentation leading to the corresponding cyanoketones was observed whereas with sultinate only the 1-methoxy-2-sulfonyl cycloalkanes were formed. (C) 2002 Published by Elsevier Science Ltd.