2-hydroxy-5-methylacetophenone benzoylhydrazone

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-hydroxy-5-methylacetophenone benzoylhydrazone
• 英文别名: benzoylhydrazone of 2-hydroxy-5-methylacetophenone；N-[(E)-1-(2-hydroxy-5-methylphenyl)ethylideneamino]benzamide
• 化学式: C₁₆H₁₆N₂O₂
• 分子量: 268.315
• InChiKey: NUEOBVRTSSKWQA-SFQUDFHCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  61.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-hydroxy-5-methylacetophenone benzoylhydrazone 以71%的产率得到
  参考文献：
  名称：

  Moriatry Robert M., Berglung Bruce A., Rao M. Suresh Chander, Synthesis, (1993) N 3, S 318- 321

  摘要：

  DOI：
• 作为产物：
  描述：

  2-羟基-5-甲基苯乙酮 、 苯甲酰肼 以0%的产率得到
  参考文献：
  名称：

  Moriatry Robert M., Berglung Bruce A., Rao M. Suresh Chander, Synthesis, (1993) N 3, S 318- 321

  摘要：

  DOI：

文献信息

• FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER
  申请人：Young David H.

  公开号：US20120148682A1

  公开（公告）日：2012-06-14

  The present invention relates to the use of hydrazone compounds and copper for controlling the growth of fungi.

  本发明涉及使用腙类化合物和铜控制真菌生长。
• SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER
  申请人：Young David H.

  公开号：US20120010075A1

  公开（公告）日：2012-01-12

  The present invention relates to the use of mixtures containing hydrazone compounds and copper for controlling the growth of fungi.

  本发明涉及使用含有肼化合物和铜的混合物来控制真菌生长。
• Synthesis, structure, solution chemistry and the electronic effect of para substituents on the vanadium center in a family of mixed-ligand [VVO(ONO)(ON)] complexes
  作者：Tapas Ghosh、Bipul Mondal、Tarun Ghosh、Manas Sutradhar、Gurunath Mukherjee、Michael G.B. Drew

  DOI：10.1016/j.ica.2006.10.003

  日期：2007.4

  Four tridentate dibasic ONO donor hydrazone ligands derived from the condensation of benzoylhydrazine with either 2-hydroxyacetophenone or its para substituted derivatives (H2L1-4, general abbreviation H2L) have been used as primary ligands and 8-hydroxyquinoline (Hhq, a bidentate monobasic ON donor species) has been used as auxiliary ligand. The reaction of [(VO)-O-IV(acac)21 with H2L in methanol followed by the addition of Hhq in equimolar ratio under aerobic condition afforded the mixed-ligand oxovanadium(V) complexes of the type [(VO)-O-V(L)(hq)] (1-4) in excellent yield. The X-ray structure of the compound [(VO)-O-V(L-4)(hq)] (4) indicates that the H2L4 ligand is bonded with vanadium meridionally in a tridentate dinegative fashion through its deprotonated phenolic-O, deprotonated enolic-O and imine-N atoms. The V-O bond length order is: oxo < phenolato < enolato. H-1 NMR spectra of 4 in CDCl3 solution indicates that it's solid-state structure is retained in solution. Complexes are diamagnetic and exhibit only ligand to metal charge transfer (LMCT) transition band near 530 nm in CH2Cl2 solution in addition to intra-ligand pi-pi* transition band near 335 rim and they display quasi-reversible one electron reduction peak near -0.10 V versus SCE in CH2Cl2 solution. lambda(max) (for LMCT transition) and the reduction peak potential (E-p(c)) values of the complexes are found to be linearly related with the Hammett (sigma) constants of the substituents in the aryloxy ring of the hydrazone ligands. lambda(max) and E-p(c) values show large dependence d lambda(max)/d sigma = 32.54 nm and dE(p)(c)/d sigma = 0.19 V, respectively, on the Hammett constant. (c) 2006 Elsevier B.V. All rights reserved.
• KOTALI, ANTIGONI;TSOUNGAS, PETROS G., TETRAHEDRON LETT., 28,(1987) N 37, 4321-4322
  作者：KOTALI, ANTIGONI、TSOUNGAS, PETROS G.

  DOI：——

  日期：——
• Synthesis, structural studies and biological activity of dioxomolybdenum(VI), dioxotungsten(VI), thorium(IV) and dioxouranium(VI) complexes with 2-hydroxy-5-methyl and 2-hydroxy-5-chloroacetophenone benzoylhydrazone
  作者：A. R. Yaul、V. V. Dhande、S. G. Bhadange、A. S. Aswar

  DOI：10.1134/s0036023611040280

  日期：2011.4

  New complexes of MoO2(VI), WO2(VI), Th(IV) and UO2(VI) with aroyl hydrazones have been prepared and characterized by various physicochemical methods. Elemental analysis suggested 1 : 1 metal : ligand stoichiometry for MoO2(VI), WO2(VI), and UO2(VI) complexes whereas 1 : 2 for Th(VI) complexes. The physicochemical studies showed that MoO2(VI), Th(IV) and UO2(VI) complexes are octahedral. The electrical conductivity of these complexes lies in the range 1.00 x 10(-7)-3.37 x 10(-11)Omega(-1) cm(-1) at 373 K. The complexes were found to be quite stable and decomposition of the complexes ended with respective metal oxide as a final product. The thermal dehydration and decomposition of these complexes were studied kinetically using both Coats-Redfern and Horowitz-Metzger methods. It was found that the thermal decomposition of the complexes follow first order kinetics. The thermodynamic parameters of the decomposition are also reported. The biological activities of ligands and their metal complexes were tested against various microorganisms.