<1,1,3,3,3-Pentafluor-2-(trimethylsiloxy)propyl>-2-phosphonsaeuredimethylester

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: <1,1,3,3,3-Pentafluor-2-(trimethylsiloxy)propyl>-2-phosphonsaeuredimethylester
• 英文别名: [2-[Dimethoxy(oxido)phosphaniumyl]-1,1,1,3,3-pentafluoropropan-2-yl]oxy-trimethylsilane；[2-[dimethoxy(oxido)phosphaniumyl]-1,1,1,3,3-pentafluoropropan-2-yl]oxy-trimethylsilane
• 化学式: C₈H₁₆F₅O₄PSi
• 分子量: 330.264
• InChiKey: JGEVHGMQPIZFOI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.78
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  50.8
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  <1,1,3,3,3-Pentafluor-2-(trimethylsiloxy)propyl>-2-phosphonsaeuredimethylester 生成 (Z)-1,3,3,3-Tetrafluorpropenyl-2-dimethylphosphat
  参考文献：
  名称：

  Additionen von trimethylsilylphosphiten an pentafluoraceton

  摘要：

  1,1,1,3,3-Pentafluoropropane-2-one (3) (pentafluoroacetone) is readily obtained from 1,1,1,3,3,3-hexafluoropropane-2-ol by dehydrofluorination using lithium bis(trimethylsilyl)amide, followed by isomerization of 1,1,3,3,3-pentafluoropropene-2-ol. Pentafluoroacetone adds trimethylsilylphosphites to yield alpha-trimethylsiloxyphosphonates which, upon thermolysis, furnish (Z)-1,3,3,3-tetrafluoropropenyldialkylphosphites and (Z)-1,3,3,3-tetrafluoro-2-trimethylsiloxypropene.

  DOI：

  10.1016/0022-1139(93)03038-n
• 作为产物：
  描述：

  五氟丙酮 、 二甲基三甲硅基膦酸酯 以79%的产率得到<1,1,3,3,3-Pentafluor-2-(trimethylsiloxy)propyl>-2-phosphonsaeuredimethylester
  参考文献：
  名称：

  Additionen von trimethylsilylphosphiten an pentafluoraceton

  摘要：

  1,1,1,3,3-Pentafluoropropane-2-one (3) (pentafluoroacetone) is readily obtained from 1,1,1,3,3,3-hexafluoropropane-2-ol by dehydrofluorination using lithium bis(trimethylsilyl)amide, followed by isomerization of 1,1,3,3,3-pentafluoropropene-2-ol. Pentafluoroacetone adds trimethylsilylphosphites to yield alpha-trimethylsiloxyphosphonates which, upon thermolysis, furnish (Z)-1,3,3,3-tetrafluoropropenyldialkylphosphites and (Z)-1,3,3,3-tetrafluoro-2-trimethylsiloxypropene.

  DOI：

  10.1016/0022-1139(93)03038-n

文献信息

• Additionen von trimethylsilylphosphiten an pentafluoraceton
  作者：Frank U. Seifert、Gerd-Volker Röschenthaler

  DOI：10.1016/0022-1139(93)03038-n

  日期：1994.8

  1,1,1,3,3-Pentafluoropropane-2-one (3) (pentafluoroacetone) is readily obtained from 1,1,1,3,3,3-hexafluoropropane-2-ol by dehydrofluorination using lithium bis(trimethylsilyl)amide, followed by isomerization of 1,1,3,3,3-pentafluoropropene-2-ol. Pentafluoroacetone adds trimethylsilylphosphites to yield alpha-trimethylsiloxyphosphonates which, upon thermolysis, furnish (Z)-1,3,3,3-tetrafluoropropenyldialkylphosphites and (Z)-1,3,3,3-tetrafluoro-2-trimethylsiloxypropene.