4-[2-(3,5-Dimethylanilino)-1,3-thiazol-4-yl]benzene-1,3-diol

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-[2-(3,5-Dimethylanilino)-1,3-thiazol-4-yl]benzene-1,3-diol
• 化学式: C₁₇H₁₆N₂O₂S
• 分子量: 312.4
• InChiKey: POLMGVQDBBXORL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  93.6
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• TYROSINASE INHIBITORS
  申请人：AVON PRODUCTS, INC.

  公开号：US20150164758A1

  公开（公告）日：2015-06-18

  The compositions and methods of described herein comprise novel ingredients effective to reduce unwanted pigmentation, such as skin discoloration, freckles, age spots, liver spots, sun damage, tans, pigmented acne marks, scars, pigmented birthmarks, hyperpigmentation, post-inflammatory hyperpigmentation, post-injury hyperpigmentation, melasma, cholasma, after-burn scar, nail stain, yellowing of skin, dark circles under eyes, and the like. The composition may include additional ingredients accordingly for a colored cosmetic, moisturizer, cleanser, toner, and the like.
• US9364405B2
  申请人：——

  公开号：US9364405B2

  公开（公告）日：2016-06-14