N,N-(dioctyl)sulfamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 英文名称: N,N-(dioctyl)sulfamide
• 英文别名: 1-[Octyl(sulfamoyl)amino]octane
• 化学式: C₁₆H₃₆N₂O₂S
• 分子量: 320.54
• InChiKey: UCNRONGVVQYZRR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  21
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  71.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,3,5-三-O-(苯基甲基)-D-呋喃阿拉伯糖 、 N,N-(dioctyl)sulfamide 在 三氟甲磺酸三甲基硅酯 作用下， 以 二氯甲烷 为溶剂， 反应 16.0h， 生成 N-(dioctyl)-N'-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)sulfamide 、 N-(dioctyl)-N'-(2,3,5-tri-O-benzyl-β-D-arabinofuranosyl)sulfamide
  参考文献：
  名称：

  Synthesis of arabinose glycosyl sulfamides as potential inhibitors of mycobacterial cell wall biosynthesis

  摘要：

  A series of arabinose glycosyl sulfamides with varying alkyl chain types and lengths were synthesised as mimics of decaprenolphosphoarabinose (DPA), and as potential inhibitors of mycobacterial cell wall biosynthesis. Unprecedented conversion of the desired furanose to the thermodynamically more stable pyranose form occurred during final de-protection. Biological testing against Mycobacterium smegmatis revealed low to moderate anti-mycobacterial activity with marked dependence on alkyl chain length, which in the case of mono-substituted sulfamides was maximal for a C-10 chain. (C) 2015 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2015.07.050
• 作为产物：
  描述：

  二正辛胺 在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 32.5h， 生成 N,N-(dioctyl)sulfamide
  参考文献：
  名称：

  Synthesis of arabinose glycosyl sulfamides as potential inhibitors of mycobacterial cell wall biosynthesis

  摘要：

  A series of arabinose glycosyl sulfamides with varying alkyl chain types and lengths were synthesised as mimics of decaprenolphosphoarabinose (DPA), and as potential inhibitors of mycobacterial cell wall biosynthesis. Unprecedented conversion of the desired furanose to the thermodynamically more stable pyranose form occurred during final de-protection. Biological testing against Mycobacterium smegmatis revealed low to moderate anti-mycobacterial activity with marked dependence on alkyl chain length, which in the case of mono-substituted sulfamides was maximal for a C-10 chain. (C) 2015 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2015.07.050

文献信息

• MISCHUNGEN ZUR HERSTELLUNG VON PHOTOAKTIVEN SCHICHTEN FÜR ORGANISCHE SOLARZELLEN UND ORGANISCHE PHOTODETEKTOREN
  申请人：Heliatek GmbH

  公开号：EP2168181B1

  公开（公告）日：2021-05-12
• ORGANIC DYES COMPRISING A HYDRAZONE MOIETY AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS
  申请人：BASF SE

  公开号：EP2870204A2

  公开（公告）日：2015-05-13
• US9831042B2
  申请人：——

  公开号：US9831042B2

  公开（公告）日：2017-11-28
• [EN] ORGANIC DYES COMPRISING A HYDRAZONE MOIETY AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS<br/>[FR] COLORANTS ORGANIQUES COMPRENANT UNE PARTIE D'HYDRAZONE ET LEUR UTILISATION DANS DES PILES SOLAIRES À COLORANTS
  申请人：BASF SE

  公开号：WO2014006544A2

  公开（公告）日：2014-01-09

  The present invention relates to compounds of general formula (I) wherein R100 and R200 are each independently hydrogen, C1-C10-alkyl which in case of C2-alkyl may be interrupted by one and in case of C3-C10-alkyl by one or two non- adjacent oxygen atoms, C5-C7-cycloalkyl, aryl, aryl-C1-C10-alkyl or aryloxy-C1-C10-alkyl, D is an m-valent (m = 1, 2 or 3) donor moiety which comprises at least one carbon- carbon or carbon-heteroatom double bond and/or at least one unfused or fused carbo- or heterocyclic ring, A is an acceptor moiety which comprises at least one carbon- carbon or carbon-heteroatom double bond and/or at least one unfused or fused carbo- or heterocyclic ring, and the donor moiety D and the acceptor moiety A are π- conjugated to one another. Furthermore, the present invention relates to the use of compounds of formula (I) for producing dye-sensitized solar cells and to dye-sensitized solar cells comprising compounds of formula (I).
• Synthesis of arabinose glycosyl sulfamides as potential inhibitors of mycobacterial cell wall biosynthesis
  作者：Kajitha Suthagar、Andrew J.A. Watson、Brendan L. Wilkinson、Antony J. Fairbanks

  DOI：10.1016/j.ejmech.2015.07.050

  日期：2015.9

  A series of arabinose glycosyl sulfamides with varying alkyl chain types and lengths were synthesised as mimics of decaprenolphosphoarabinose (DPA), and as potential inhibitors of mycobacterial cell wall biosynthesis. Unprecedented conversion of the desired furanose to the thermodynamically more stable pyranose form occurred during final de-protection. Biological testing against Mycobacterium smegmatis revealed low to moderate anti-mycobacterial activity with marked dependence on alkyl chain length, which in the case of mono-substituted sulfamides was maximal for a C-10 chain. (C) 2015 Elsevier Masson SAS. All rights reserved.