壬基胍 | 60062-23-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 壬基胍
• 英文名称: Nonylguanidin
• 英文别名: Nonylguanidine；2-nonylguanidine
• CAS: 60062-23-9
• 化学式: C₁₀H₂₃N₃
• mdl: MFCD20545852
• 分子量: 185.313
• InChiKey: QKVSKRWNJXMUAQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  64.4
• 氢给体数：
  2
• 氢受体数：
  1

安全信息

• 海关编码：
  2925290090

文献信息

• GUANIDINE COMPOUND AND BACTERICIDE
  申请人：Nippon Soda Co., Ltd.

  公开号：EP3305759A1

  公开（公告）日：2018-04-11

  A novel guanidine compound having excellent fungicidal activity is represented by formula [I]. (In the formula, Y represents a divalent group represented by formula [II] (wherein each of R7-R9 independently represents a hydrogen atom or the like) or the like; each of X and Z independently represents an unsubstituted or substituted alkylene group or the like; each of Q1 and Q2 independently represents a single bond or the like; each of A1 and A2 independently represents an unsubstituted or substituted divalent heterocyclic compound residue or the like; and each of R1-R6 independently represents a hydrogen atom or the like.)

  一种具有优异杀菌活性的新型胍类化合物由式[I]表示。(在该式中，Y 代表由式[II]（其中 R7-R9 中的每一个独立地代表氢原子或类似物）代表的二价基团或类似物；X 和 Z 中的每一个独立地代表未取代或取代的亚烷基或类似物；Q1 和 Q2 中的每一个独立地代表单键或类似物；A1 和 A2 中的每一个独立地代表未取代或取代的二价杂环化合物残基或类似物；以及 R1-R6 中的每一个独立地代表氢原子或类似物）。
• Mixtures and compositions comprising Paenibacillus strains or metabolites thereof and other biopesticides
  申请人：BASF SE

  公开号：US11185078B2

  公开（公告）日：2021-11-30

  The present invention relates to novel mixtures comprising, as active components, at least one isolated bacterial strain, which is a member of the genus Paenibacillus, or a cell-free extract thereof or at least one metabolite thereof, and at least one other biopesticide. The present invention also relates to compositions comprising at least one of such bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and at least one other biopesticide. The present invention also relates to a method of controlling or suppressing plant pathogens or preventing plant pathogen infections by applying such composition. The present invention also relates to mixtures of fusaricidins which are pesticidal metabolites produced by the abovementioned strains, and other biopesticides.

  本发明涉及新型混合物，其活性成分包括至少一种分离的细菌菌株（属于Paenibacillus属）或其无细胞提取物或至少一种代谢物，以及至少一种其他生物农药。本发明还涉及包含至少一种此类细菌菌株、全培养液或无细胞提取物或其馏分或至少一种代谢物以及至少一种其他生物农药的组合物。本发明还涉及一种通过施用此类组合物控制或抑制植物病原体或预防植物病原体感染的方法。本发明还涉及由上述菌株产生的杀虫代谢物 fusaricidins 和其他生物农药的混合物。
• METHOD FOR INHIBITING THE FORMATION OF SET1 FAMILY CORE COMPLEXES
  申请人：Cosgrove Michael S.

  公开号：US20100022002A1

  公开（公告）日：2010-01-28

  Disclosed in this specification is a method for inhibiting the formation of SET1 family core complexes. A guanidinium-containing molecule is used to competitively inhibit the binding of the N-SET region of a SET1 protein to WDR5, thus inhibiting the formation of the SET1 family core complex. The guanidinium-containing molecule may be, for example, an arginine-containing peptide. When bound to WDR5, the guanidinium moiety is bound between the F-133 and F-263 residues of the WDR5 when a crystal structure of the bound complex is obtained.
• COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS
  申请人：Merck Sharp & Dohme Corp.

  公开号：US20200206350A1

  公开（公告）日：2020-07-02

  The present invention relates to pegylated amino acid compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein X, R 1 , R 2 , R 3A , R 3B and n are as defined herein. The present invention also relates to compositions which comprise a pegylated amino acid compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, in combination with a high concentration of an active biological ingredient (ABI). In embodiments of the invention, the ABI is an anti-PD-1 antibody or antigen binding fragment thereof that specifically binds human programmed death receptor 1 (PD-1). The invention further relates to methods for lowering the viscosity of an aqueous solution of a pharmaceutical composition comprising adding a compound of the invention to the solution. The invention also provides methods for treating a pathological disease or condition, such as cancer, by administering to a subject in need of such treatment a therapeutically effective amount of a pharmaceutical composition of the invention.
• US8133690B2
  申请人：——

  公开号：US8133690B2

  公开（公告）日：2012-03-13