[EN] MACROMOLECULAR PRODRUGS FOR HARD TISSUE AND METHODS OF USE THEREOF<br/>[FR] PROMÉDICAMENTS MACROMOLÉCULAIRES POUR TISSU DUR ET LEURS PROCÉDÉS D'UTILISATION
申请人:NEW YORK SOC RUPTURED & CRIPPLED MAINTAINING HOSPITAL FOR SPECIAL SURGERY
公开号:WO2014036548A1
公开(公告)日:2014-03-06
Compositions for intravenous administration and methods for treating bone diseases, disorders, and fractures comprising macromolecular prodrugs of hydrophobic bone anabolic agents are provided. Specifically, novel macromolecular amphiphilic prodrugs wherein at least three molecules of simvastatin are conjugated to polyethylene glycol, which spontaneously form micelles in aqueous solutions are provided.
The present invention concerns functionalized photoreactive compounds of formula (I), that are particularly useful in materials for the alignment of liquid crystals. Due to the adjunction of an electron withdrawing group to specific molecular systems bearing an unsaturation directly attached to two unsaturated ring systems, exceptionally high photosensitivities, excellent alignment properties as well as good mechanical robustness could be achieved in materials comprising said functionalized photoreactive compounds of the invention.
COSMETIC PROCESS FOR MAKING-UP AND/OR CARING FOR THE SKIN AND/OR THE LIPS
申请人:L'OREAL
公开号:US20150290116A1
公开(公告)日:2015-10-15
A cosmetic process for making-up and/or caring for skin and/or lips, includes the application to skin and/or lips of a cosmetic composition including, in a physiologically acceptable medium, at least one supramolecular polymer and at least one hydrophobic film-forming polymer. Particular compositions may be used in the process.
RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS
申请人:ZEON CORPORATION
公开号:US20160297755A1
公开(公告)日:2016-10-13
The present invention involves a radical polymerization initiator comprising an organotellurium compound represented by a formula (1), wherein R
1
represents an alkyl group or the like, each of R
2
and R
3
independently represents a hydrogen atom or the like, and each of R
4
, R
5
, and R
6
independently represents a hydrogen atom or the like. The present invention provides: a radical polymerization initiator that is useful for producing a polymer that includes a double bond at the molecular terminal; and a method for producing a polymer that utilizes the radical polymerization initiator.
The invention relates to novel composite materials comprising
(a) an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization; and
(b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic macromonomers of formula (1) as outlined in the claims to the bulk material surface provided with the initiator radicals and polymerizing said macromonomers.
The composite materials of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.