(Z)-but-2-enedioic acid;(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (Z)-but-2-enedioic acid;(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
• 化学式: C30H52N8O10S2
• 分子量: 748.9
• InChiKey: VLRABWSXHYVLQI-WILCOHJVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.72
• 重原子数：
  50
• 可旋转键数：
  16
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  291
• 氢给体数：
  6
• 氢受体数：
  20

文献信息

• DRUG DELIVERY SYSTEM
  申请人：Schering Oy

  公开号：EP1427390A1

  公开（公告）日：2004-06-16
• DELIVERY OF NUCLEIC ACIDS, PROTEINS AND SMALL MOLECULES IN VITREOUS VESICULAR BODIES
  申请人：CORNELL UNIVERSITY

  公开号：US20190216857A1

  公开（公告）日：2019-07-18

  The present invention relates to compositions of aqueous humor and/or vitreous humor derived extracellular vesicles and their use for the delivery of therapeutic agents to ocular tissues for the treatment of ophthalmic diseases. Further disclosed are methods of making the compositions. Methods of treating and diagnosing an ocular condition are also disclosed.
• [EN] DRUG DELIVERY SYSTEM<br/>[FR] SYSTEME DE LIBERATION DE MEDICAMENT
  申请人：LEIRAS OY

  公开号：WO2003017971A1

  公开（公告）日：2003-03-06

  The invention relates to a delivery system comprising at least one core and a membrane. The core and the membrane consist of an elastomer composition comprising e.g poly (dimethylsiloxane), a siloxane-based elastomer comprising 3,3,3-trifluorpropyl groups attached to the Si-atoms of the siloxane units and/or poly(alkylene oxide) groups, present as alkoxy-terminated grafts or blocks linked to the polysiloxane units by silicon-carbon bonds, or as a mixture of these forms. The delivery system is preferably an implant or an intrauterine, intracervical or intravaginal system.