(2Z,4Z)-N-[(E)-3-(7,15-dihydroxy-9-oxo-10,17-dioxatricyclo[11.3.1.03,8]heptadeca-3(8),4,6-trien-11-yl)prop-1-enyl]hepta-2,4-dienamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: (2Z,4Z)-N-[(E)-3-(7,15-dihydroxy-9-oxo-10,17-dioxatricyclo[11.3.1.03,8]heptadeca-3(8),4,6-trien-11-yl)prop-1-enyl]hepta-2,4-dienamide
• 化学式: C₂₅H₃₁NO₆
• 分子量: 441.5
• InChiKey: MVOORUCGKRDJFW-UYSGNFFCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• Erythropoietin: remodeling and glycoconjugation of erythropoietin
  申请人：DeFrees Shawn

  公开号：US20070027068A1

  公开（公告）日：2007-02-01

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• Glycopegylation methods and proteins/peptides produced by the methods
  申请人：DeFrees Shawn

  公开号：US20070026485A1

  公开（公告）日：2007-02-01

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• ERYTHROPOIETIN: REMODELING AND GLYCOCONJUGATION OF ERYTHROPOIETIN
  申请人：DeFrees Shawn

  公开号：US20070042458A1

  公开（公告）日：2007-02-22

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• Factor VIII: Remodeling and glycoconjugation of factor VIII
  申请人：DeFrees Shawn

  公开号：US20080070275A1

  公开（公告）日：2008-03-20

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• Glycoconjugation methods and proteins/peptides produced by the methods
  申请人：DeFrees Shawn

  公开号：US20080146494A1

  公开（公告）日：2008-06-19

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.