2-[1-(aminomethyl)-6,7-dimethoxyisoquinolin-4-yl]-N-(3-methoxypropyl)acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: 2-[1-(aminomethyl)-6,7-dimethoxyisoquinolin-4-yl]-N-(3-methoxypropyl)acetamide
• 化学式: C₁₈H₂₅N₃O₄
• 分子量: 347.4
• InChiKey: KKWBNGAQDBUVKK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  25
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  95.7
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Enhancement of growth hormone levels with a dipeptidyl peptidase IV inhibitor and a growth hormone secretagogue
  申请人：Hogenhuis Wladimir

  公开号：US20070123470A1

  公开（公告）日：2007-05-31

  The present invention is directed to methods for increasing levels of endogenous growth hormone in a mammal by the administration of a combination of a dipeptidyl peptidase IV (DP-IV) inhibitor and a growth hormone secretagogue.
• [EN] ENHANCEMENT OF GROWTH HORMONE LEVELS WITH A DIPEPTIDYL PEPTIDASE IV INHIBITOR AND A GROWTH HORMONE SECRETAGOGUE<br/>[FR] AMELIORATION DU NIVEAU HORMONAL DE CROISSANCE
  申请人：MERCK & CO INC

  公开号：WO2005042003A1

  公开（公告）日：2005-05-12

  The present invention is directed to methods for increasing levels of endogenous growth hormone in a mammal by the administration of a combination of a dipeptidyl peptidase IV (DP-IV) inhibitor and a growth hormone secretagogue.