[(3S,9S,13S,14S)-13-methyl-17-oxo-2,3,4,6,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: [(3S,9S,13S,14S)-13-methyl-17-oxo-2,3,4,6,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate
• 化学式: C₁₈H₂₄O₅S
• 分子量: 352.4
• InChiKey: WNXXYKUWNMBAPS-QUCGAITQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  89
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• PHARMACEUTICAL COMPOSITIONS OF CONJUGATED ESTROGENS AND METHODS OF ANALYZING MIXTURES CONTAINING ESTROGENIC COMPOUNDS
  申请人：Endeavor Pharmaceuticals

  公开号：EP1267852A2

  公开（公告）日：2003-01-02
• US6855703B1
  申请人：——

  公开号：US6855703B1

  公开（公告）日：2005-02-15
• [EN] PHARMACEUTICAL COMPOSITIONS OF CONJUGATED ESTROGENS AND METHODS OF ANALYZING MIXTURES CONTAINING ESTROGENIC COMPOUNDS<br/>[FR] COMPOSITIONS PHARMACEUTIQUES D'OESTROGENES CONJUGUES ET METHODES D'ANALYSE DE MELANGES CONTENANT DES COMPOSES OESTROGENIQUES
  申请人：ENDEAVOR PHARMACEUTICALS

  公开号：WO2001068074A2

  公开（公告）日：2001-09-20

  A composition of matter is provided having a mixture of active estrogenic compounds. The mixture is present in chemically pure form. The mixture includes salts of conjugated estrone, conjugated equilin, conjugated Δ8,9-dehydroestrone, conjugated 17α-estradiol, conjugated 17α-dihydroequilin, conjugated 17α-dihydroequilin, conjugated 17β-estradiol, conjugated equilenin, conjugated 17α-dihydroequilenin, and conjugated 17β-dihydroequilenin. The mixture also contains the same essential estrogenic compounds present in naturally derived equine conjugated estrogens. Drug products including the composition of matter are also provided, as are methods of using these drug products to treat mammals in need of treatment. Methods of analyzing mixtures containing conjugated estrogens are also provided.