1,2-亚乙二次氮四丙醇与环氧乙烷和甲基环氧丙烷的聚合物

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 1,2-亚乙二次氮四丙醇与环氧乙烷和甲基环氧丙烷的聚合物
• 中文别名: 1,2-乙二胺乙氧基化丙氧基化物；甲基环氧乙烷与1,2,-乙二胺和环氧乙烷的聚合物
• 英文名称: 2-[1-[1-[2-[Bis[2-[2-(2-hydroxyethoxy)propoxy]propyl]amino]ethyl-[2-[2-(2-hydroxyethoxy)propoxy]propyl]amino]propan-2-yloxy]propan-2-yloxy]ethanol
• 英文别名: 2-[1-[1-[2-[bis[2-[2-(2-hydroxyethoxy)propoxy]propyl]amino]ethyl-[2-[2-(2-hydroxyethoxy)propoxy]propyl]amino]propan-2-yloxy]propan-2-yloxy]ethanol
• 化学式: C₃₄H₇₂N₂O₁₂
• 分子量: 700.9
• InChiKey: BFKFABWTAFNFID-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  48
• 可旋转键数：
  35
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  161
• 氢给体数：
  4
• 氢受体数：
  14

文献信息

• PRODUCTION METHOD OF MEDICAL POLYOXYPROPYLENE POLYMER AND PRODUCTION METHOD OF MEDICAL POLYOXYPROPYLENE/POLYOXYETHYLENE BLOCK COPOLYMER
  申请人：NOF CORPORATION

  公开号：US20160264730A1

  公开（公告）日：2016-09-15

  A method of producing a medical polyoxypropylene polymer and a polyoxypropylene/polyoxyethylene block copolymer including (A) adding to a polyoxypropylene polymer which is obtained by ring-opening polymerization of propylene oxide to a starting substance having an active hydrogen reacting with the propylene oxide and contains allyl ether as an impurity, a tertiary alkoxide of alkali metal in an excess amount based on a molar number of the active hydrogen of the starting substance and heat treating at 115° C. or less to isomerize the allyl ether to propenyl ether; and (B) adding a mineral acid to the product obtained in step (A) to adjust pH to 4 or less and treating at 70° C. or less to hydrolyze the propenyl ether. Also disclosed is a method of producing a medical polyoxypropylene/polyoxyethylene block copolymer which includes performing ring-opening polymerization of ethylene oxide to the polyoxypropylene polymer obtained above.
• US9777113B2
  申请人：——

  公开号：US9777113B2

  公开（公告）日：2017-10-03