斯佩西亭 | 14382-79-7

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 柯楠因类生物碱
• 中文名称: 斯佩西亭
• 中文别名: 吲哚并[2,3-a]喹嗪-2-乙酸,3-乙基-1,2,3,4,6,7,12,12b-八氢-8-甲氧基-a-(甲氧基亚甲基)-,甲基酯,(aE,2S,3S,12bR)-
• 英文名称: speciociliatine
• 英文别名: Speciociliatin；methyl (E)-2-[(2S,3S,12bR)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate
• CAS: 14382-79-7
• 化学式: C₂₃H₃₀N₂O₄
• 分子量: 398.502
• InChiKey: LELBFTMXCIIKKX-MYLQJJOTSA-N

物化性质

• 熔点：
  97-8°C
• 沸点：
  560.3±50.0 °C(Predicted)
• 密度：
  1.22±0.1 g/cm3(Predicted)
• 溶解度：
  氯仿（微溶）、乙醇（微溶）、甲醇（微溶）

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  63.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Immunoassay for Detecting Kratom, its Constituents and their Use
  申请人：Randox Laboratories Limited

  公开号：US20140242617A1

  公开（公告）日：2014-08-28

  The invention relates to the field of drug detection and describes antibody-based components methods and kits for the detection and quantification of alkaloids of the plant kratom. The invention is underpinned by novel antibodies which specifically bind to mitragynine alkaloids found in the kratom plant and their metabolites.
• COMPOSITIONS CONTAINING KRATOM COMPOUNDS
  申请人：CAAMTECH LLC

  公开号：US20210113644A1

  公开（公告）日：2021-04-22

  Disclosed are compositions containing (a) a purified kratom compound chosen from the following: 7-Hydroxymitragynine, Mitragynine, Paynantheine, Speciociliatine, Speciogynine, Ajmalicine, Ciliaphylline, Corynantheidine, Corynoxine A, Corynoxine B, Isomitraphylline, Isorhynchophylline, Mitraphylline, Rhynchophylline, Speciophylline, Speciofoline, Epicatechin, 7-Hydroxyspecioliatine, 9-Hydroxycorynantheidine, Corynoxeine, Isopteropodine, Isorhynchophylline Oxindole, Tetrahydroalstonine, Mitragynine Oxindole B, and Mitragynine Oxindole A or the salts of these kratom compounds; and (b) a second active compound selected from a serotonergic drug, a purified psilocybin derivative, a purified cannabinoid, or a purified terpene. The disclosure also relates to formulations, including pharmaceutical formulations, of such a composition and an excipient. Also disclosed are methods of regulating the activity of a neurotransmitter receptor and methods of treating a psychological disorder, a compulsive disorder, or a depressive disorder.
• US9952206B2
  申请人：——

  公开号：US9952206B2

  公开（公告）日：2018-04-24