1,7-萘啶-5-胺 | 123434-45-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 中文名称: 1,7-萘啶-5-胺
• 英文名称: 5-amino-1,7-naphthyridine
• 英文别名: 1,7-Naphthyridin-5-amine
• CAS: 123434-45-7
• 化学式: C₈H₇N₃
• mdl: MFCD18384559
• 分子量: 145.164
• InChiKey: FVLLRUVQRRMQTI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  8-chloro-5-nitro-1,7-naphthyridine 生成 1,7-萘啶-5-胺
  参考文献：
  名称：

  WOZNIAK M.; PLAS H. C. VAN DER, J. HETEROCYCL. CHEM., 1978, 15, NO 5, 731-736

  摘要：

  DOI：

文献信息

• [EN] COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS<br/>[FR] COMPOSÉS ET COMPOSITIONS SERVANT DE MODULATEURS DE L'ACTIVITÉ DES TLR
  申请人：IRM LLC

  公开号：WO2009111337A1

  公开（公告）日：2009-09-11

  The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: X3 is N; X4 is N Or CR3; X5 is -CR4=CR5.

  该发明提供了一类新型化合物，包括这些化合物的药物组合物以及使用这些化合物来治疗或预防与Toll样受体相关的疾病或紊乱的方法，包括TLR7和TLR8。在一个方面，这些化合物可用作辅助剂，以增强疫苗的效果（公式I），其中：X3为N；X4为N或CR3；X5为-CR4=CR5。
• ORGANIC LIGHT-EMITTING DEVICE
  申请人：Samsung Display Co., Ltd.

  公开号：EP3185331A1

  公开（公告）日：2017-06-28

  An organic light-emitting device comprising: a first electrode; a second electrode facing the first electrode; an emission layer between the first electrode and the second electrode; a hole transport region between the first electrode and the emission layer; and an electron transport region between the emission layer and the second electrode, wherein at least one selected from the hole transport region and the emission layer comprises a first compound represented by Formula 1A or 1B, and at least one selected from the hole transport region and the electron transport region comprises a second compound represented by Formula 2:

  一种有机发光器件，包括：第一电极；面向第一电极的第二电极；位于第一电极和第二电极之间的发射层；位于第一电极和发射层之间的空穴传输区域；以及位于发射层和第二电极之间的电子传输区域，其中至少一种选自空穴传输区域和发射层的化合物由式 1A 或 1B 表示的第一种化合物组成，而至少一种选自空穴传输区域和电子传输区域的化合物由式 2 表示的第二种化合物组成：
• CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THIN FILM FORMED FROM THE COMPOSITION
  申请人：Samsung Display Co., Ltd.

  公开号：EP3663283A1

  公开（公告）日：2020-06-10

  Provided are a condensed cyclic compound, a composition including the same, and an organic light-emitting device including a thin film formed from the composition. The condensed cyclic compound is represented by following Formula, has a molecular weight of about 10,000 or less, and comprises at least one cross-linkable group:

  本文提供了一种缩合环状化合物、一种包括该化合物的组合物以及一种包括由该组合物形成的薄膜的有机发光器件。缩合环状化合物如下式所示，分子量约为 10,000 或更小，并包含至少一个可交联基团：
• CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME
  申请人：Samsung Display Co., Ltd.

  公开号：EP3799144A1

  公开（公告）日：2021-03-31

  An organic light-emitting device includes a condensed cyclic compound represented by Formula 1, where at least one of X4 to X11 is C(Rx), and Rx is a group represented by Formula 2: The condensed cyclic compound represented by Formula 1 has a planar conformation because of the single bond linking the 8 and 8' positions of the spirobifluorene moiety. Accordingly, the condensed cyclic compound may provide the organic light-emitting device with suitable hole mobility and thermal stability.

  一种有机发光器件包括由式 1 表示的缩合环状化合物，其中 X4 至 X11 中至少有一个是 C(Rx)，而 Rx 是由式 2 表示的基团： 由式 1 表示的缩合环状化合物具有平面构象，因为螺二芴分子的 8 和 8'位之间有单键连接。因此，缩合环状化合物可为有机发光器件提供适当的空穴迁移率和热稳定性。
• ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME
  申请人：Samsung Display Co., Ltd.

  公开号：EP3913699A1

  公开（公告）日：2021-11-24

  An organic light-emitting device includes: a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode and including an emission layer, wherein the emission layer includes a host and a dopant, the host includes a first host compound, a second host compound, and a third host compound, and the first host compound satisfies Conditions 1-1 and 1-2: S1H1>3eV T1H1>2.8eV, wherein, in Conditions 1-1 and 1-2, S1(H1) indicates a lowest excitation singlet energy level of the first host compound, and T1(H1) indicates a lowest excitation triplet energy level of the first host compound.

  一种有机发光器件包括：第一电极；面向第一电极的第二电极；以及位于第一电极和第二电极之间并包括发射层的有机层，其中发射层包括宿主和掺杂剂，宿主包括第一宿主化合物、第二宿主化合物和第三宿主化合物，第一宿主化合物满足条件1-1和1-2：S1H1>3eV T1H1>2.8eV，其中，在条件 1-1 和 1-2 中，S1(H1) 表示第一宿主化合物的最低激发单电子能级，T1(H1) 表示第一宿主化合物的最低激发三电子能级。