曲比氯铵 | 79-90-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 曲比氯铵
• 英文名称: Triclobisonium chloride
• 英文别名: 6-[dimethyl-[4-(2,2,6-trimethylcyclohexyl)butan-2-yl]azaniumyl]hexyl-dimethyl-[4-(2,2,6-trimethylcyclohexyl)butan-2-yl]azanium;dichloride
• CAS: 79-90-3
• 化学式: C36H74Cl2N2
• 分子量: 605.9
• InChiKey: JMTNOKRGERWNME-UHFFFAOYSA-L

物化性质

• 熔点：
  243-253° (dec)

计算性质

• 辛醇/水分配系数(LogP)：
  3.97
• 重原子数：
  40
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• 危险品运输编号：
  UN 3264 8/PG 3

文献信息

• [EN] PROCESS FOR PREPARING ALKOXY ARYL ESTER<br/>[FR] PROCÉDÉ POUR LA PRÉPARATION D'ESTER D'ACIDE ALCOXYARYLIQUE
  申请人：SAUDI BASIC IND CORP SABIC

  公开号：WO2013053455A1

  公开（公告）日：2013-04-18

  The invention relates to a process for preparing a compound represented by the formula 1 which compound may optionally be further mono- or di- substituted with halogen atoms, alkyl groups having 1 to 4 C- atoms and/or alkoxy groups having 1 to 4 C- atoms, wherein R is methyl or ethyl group, comprising the step of: contacting a corresponding compound represented by the formula 2 which compound is not further substituted or further mono- or di- substituted in corresponding positions with halogen atoms, alkyl groups having 1 to 4 C- atoms and/or alkoxy groups having a to 4 C-atoms, with an alkylating agent, wherein the alkylating agent is a compound of the formula (RO)2SO2 or RX, wherein R has the above meaning and X is halogen, in the presence of a bis-quaternary ammonium salt or a polymeric quaternary ammonium salt, in a two-phase system of an aqueous solution of a base and an organic solvent.

  该发明涉及一种制备代表为式1的化合物的方法，该化合物可以选择性地进一步单取代或双取代于卤原子、具有1至4个碳原子的烷基基团和/或具有1至4个碳原子的烷氧基团，其中R为甲基或乙基基团，包括以下步骤：将代表为式2的相应化合物与烷基化试剂接触，其中所述化合物在相应位置未被进一步取代或进一步单取代或双取代于卤原子、具有1至4个碳原子的烷基基团和/或具有1至4个碳原子的烷氧基团，所述烷基化试剂为具有上述含义的化合物(RO)2SO2或RX，其中R具有上述含义，X为卤素，在双季铵盐或聚合季铵盐的存在下，在碱的水溶液和有机溶剂的两相体系中进行。
• PROCESS FOR THE PREPARATION OF ISOBUTYLIDENE DIUREA
  申请人：SAUDI BASIC INDUSTRIES CORPORATION

  公开号：US20150183729A1

  公开（公告）日：2015-07-02

  The invention relates to a process comprising: reacting isobutyraldehyde with an aqueous solution of urea in the presence of a phase transfer catalyst to form isobutylidene diurea. Preferably, the phase transfer catalyst is a quaternary ammonium salt, more preferably benzyltriethylammonium chloride. Even more preferably, the process is performed in one pot.

  本发明涉及一种工艺，包括：在相转移催化剂的存在下，将异丁醛与尿素水溶液反应，形成异丁基亚甲基二脲。优选地，相转移催化剂是季铵盐，更优选的是苄基三乙基铵氯化物。更加优选的是，在一个反应釜中进行该工艺。
• Urinary drainage container comprising external source of biocide
  申请人：ALZA CORPORATION

  公开号：EP0357318A2

  公开（公告）日：1990-03-07

  A patient-care apparatus comprising a container (10) for receiving a biological fluid, and a delivery device (16) on the outside of the container, which device comprises a biocide (21) that is released to the container for preventing the multiplication of and/or aiding in the elimination of the presence of unwanted pathogens in the container.

  一种病人护理设备，包括一个用于接收生物液体的容器（10）和一个位于容器外部的输送装置（16），该装置包括一种生物杀灭剂（21），生物杀灭剂被释放到容器中，用于防止容器中不需要的病原体繁殖和/或帮助消除容器中存在的病原体。
• Alcohol based anti-microbial compositions with cosmetic appearance
  申请人：ETHICON INC.

  公开号：EP0930065A2

  公开（公告）日：1999-07-21

  The present invention provides antimicrobial compositions containing high levels of alcohol, carbomer polymers and antimicrobial agents. The present invention provides stable, high viscosity antimicrobial formulations possessing cosmetic characteristics.

  本发明提供了含有大量酒精、卡波姆聚合物和抗菌剂的抗菌组合物。本发明提供稳定的高粘度抗菌配方，具有化妆品特性。
• Biocidal locks
  申请人：Biolink Corporation

  公开号：EP1245247A1

  公开（公告）日：2002-10-02

  Disclosed herein is an internal prosthetic device comprising: (a) means for providing a continuous flowpath, crossing a patient's skin, between an external-to-patient site and an internal-to-patient site; (b) means for blocking the flowpath; and (c) a biocidal lock comprising: (i) an anticoagulant; and (ii) a non-antibiotic biocide.

  本文所披露的内部修复装置包括 (a) 在患者皮肤外部和患者皮肤内部之间提供连续流动路径的装置； (b) 用于阻断流动路径的装置；以及 (c) 生物杀菌锁，包括 (i) 抗凝剂；和 (ii) 非抗生素杀菌剂。