Three new lignans, (+)-fraxiresinol [(1S, 2R, 5R, 6S)-1-hydroxy-2-(3, 5-dimethoxy-4-hydroxyphenyl)-6-(4-hydroxy-3-methoxyphenyl)-3, 7-dioxabicyclo [3.3.0] octane] (3), (+)-1-hydroxysyringaresinol (4) and (+)-1-hydroxypinoresinol-4'-β-D-glucoside (8), and five known lignans, (+)-pinoresinol (1), (+)-1-hydroxypinoresinol (2), (-)-olivil (5), (+)-cyclo-olivil (6) and (+)-pinoresinol-β-D-glucoside (7), were isolated from the bark of Fraxinus mandshurica RUPR. var. japonica MAXIM and the bark of F. japonica BLUME (Oleaceae). Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence.
三种新的
木脂素,(+)-fraxiresinol [(1S, 2R, 5R, 6S)-1-hydroxy-2-(3, 5-dimethoxy-4-hydroxyphenyl)-6-(4-hydroxy-3-methoxyphenyl)-3, 7-dioxabicyclo [3.3.0] octane] (3)、(+)-1-羟基丁香
树脂醇 (4) 和 (+)-1-hydroxypinoresinol-4'-β-D-glucoside (8),以及五种已知的
木脂素,(+)-pinoresinol (1)、(+)-pinoresinol (1)、(+)-1-hydroxypinoresinol (2)、(-)-olivil (5)、(+)-cyclo-olivil (6) 和(+)-pinoresinol-β-D-glucoside (7)。japonica MAXIM 和 F. japonica BLUME(油茶科)树皮中分离出来。根据光谱分析和
化学证据阐明了它们的结构。