地菲林葡萄糖苷 | 25047-48-7

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 木脂素苷
• 中文名称: 地菲林葡萄糖苷
• 英文名称: 9-(benzo[d][1,3]dioxol-5-yl)-6,7-dimethoxy-4-(tetrahydro-3-hydroxy-4,5-dimethoxy-2H-pyran-2-yloxy)naphtho[2,3-c]furan-1(3H)-one
• 英文别名: Cleistanthin；9-(1,3-benzodioxol-5-yl)-4-(3-hydroxy-4,5-dimethoxyoxan-2-yl)oxy-6,7-dimethoxy-3H-benzo[f][2]benzofuran-1-one
• CAS: 25047-48-7
• 化学式: C₂₈H₂₈O₁₁
• 分子量: 540.524
• InChiKey: FCOQWUOWHWHTJP-UHFFFAOYSA-N

物化性质

• 熔点：
  135.5°C
• 沸点：
  535.98°C (rough estimate)
• 密度：
  1.2852 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  39
• 可旋转键数：
  7
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  120
• 氢给体数：
  1
• 氢受体数：
  11

文献信息

• Agents for Eliminating Tumour-Initiating Cells
  申请人：GODAVARI BIOREFINERIES LIMITED

  公开号：US20150328245A1

  公开（公告）日：2015-11-19

  The present invention provides agents useful for eliminating tumour initiating cells, compositions thereof, uses thereof and methods of using the same.
• ARYLNAPHTHALENE LACTONE DERIVATIVES AND METHODS OF MAKING AND USING THEREOF
  申请人：OHIO STATE INNOVATION FOUNDATION

  公开号：US20170119806A1

  公开（公告）日：2017-05-04

  A series of natural products including phyllanthusum, an arylnaphthalene lignan derivative, with anticancer and antitumor and immunostimulating activity are disclosed. The invention further encompasses methods of adding water solubilizing groups to the arylrings that include phosphonyl groups.
• [EN] AGENTS FOR ELIMINATING TUMOUR-INITIATING CELLS<br/>[FR] AGENTS POUR ÉLIMINER DES CELLULES D'INITIATION TUMORALE
  申请人：GODAVARI BIOREFINERIES LTD

  公开号：WO2014097318A2

  公开（公告）日：2014-06-26

  The present invention provides agents useful for eliminating tumour initiating cells, compositions thereof, uses thereof and methods of using the same.
• [EN] USE OF COMPOUNDS FOR TREATING VIRAL INFECTIONS<br/>[FR] UTILISATION DE COMPOSÉS POUR LE TRAITEMENT D'INFECTIONS VIRALES
  申请人：GODAVARI BIOREFINERIES LTD

  公开号：WO2021229602A1

  公开（公告）日：2021-11-18

  The invention relates to use of a compound of Formula I for inhibition of V-ATPase activity in a cell and a method of treating viral infections using the compounds of Formula I.