棕榈酰胆碱 | 13100-90-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 棕榈酰胆碱
• 英文名称: Palmitoylcholine
• 英文别名: 2-hexadecanoyloxyethyl(trimethyl)azanium
• CAS: 13100-90-8
• 化学式: C21H44NO2+
• 分子量: 342.6
• InChiKey: ODYPFMHOOQOHEF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  24
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Sustained release pharmaceutical compositions
  申请人：Zhang Yongfeng Jack

  公开号：US20070154546A1

  公开（公告）日：2007-07-05

  The present invention relates to a pharmaceutical composition comprising a salt of quaternary ammonium of an acid drug in the form of a suspension or an emulsion, suitable for parenteral administration and providing a sustained release of the drug. In one preferred embodiment, the present invention is directed to a long term sustained release composition for parenteral administration, comprising a salt of heparin or low molecular weight heparin in an emulsion with a salt of acylcholine, for the prevention and treatment of venous thrombosis and pulmonary embolism.

  本发明涉及一种制药组合物，包括酸性药物的季铵盐，其以悬浮液或乳状液的形式适用于肌内给药，并提供药物的持续释放。在一个优选实施例中，本发明涉及一种用于肌内给药的长期持续释放组合物，包括肝素盐或低分子量肝素与乙酰胆碱盐的乳状液，用于预防和治疗静脉血栓和肺栓塞。
• Liquid detergent composition for improved greasy soil removal
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0000224A1

  公开（公告）日：1979-01-10

  Liquid detergent compositions containing specific mixtures of selected anionic, nonionic and water-soluble cationic surfactants. The compositions are especially effective in removing greasy soil from fabrics.

  液体洗涤剂组合物含有精选阴离子、非离子和水溶性阳离子表面活性剂的特定混合物。这种组合物对去除织物上的油脂污垢特别有效。
• Detergent compositions
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0051986A2

  公开（公告）日：1982-05-19

  Granular built detergent compositions containing specific mixtures of anionic surfactant alkoxylated nonionic surfactant and water-soluble cationic surfactant. In highly preferred compositions, the anionic surfactant comprises a sulfate or stulfo- nate anionic surfactant or a mixture thereof with a fatty acid soap. Especially preferred compositions comprise a mixture of sulfonate and sulfate anionic surfactants. The compositions provide enhanced oil and grease removal from fabrics together with good clay soil detergency, whiteness maintenance and foam control characteristics under realistic multicycle wash conditions.

  颗粒状内置洗涤剂组合物含有阴离子表面活性剂烷氧基化非离子表面活性剂和水溶性阳离子表面活性剂的特定混合物。 在非常优选的组合物中，阴离子表面活性剂包括硫酸盐或硫酸盐阴离子表面活性剂或其与脂肪酸皂的混合物。 特别优选的组合物包括磺酸盐和硫酸盐阴离子表面活性剂的混合物。 在实际多循环洗涤条件下，该组合物可增强织物的油脂去除效果，同时具有良好的粘土去污力、白度保持力和泡沫控制特性。
• Choline esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities
  申请人：Merck & Co., Inc.

  公开号：EP0214898A2

  公开（公告）日：1987-03-18

  Choline esters are used as drug absorption enhancing agents for drugs which are poorly absorbed from the nasal, oral, and vaginal cavities.

  胆碱酯可作为药物吸收促进剂，用于促进鼻腔、口腔和阴道吸收不良的药物。
• Pharmaceutical composition containing choline ester salts for enhancing gastrointestinal tract absorption
  申请人：Merck & Co., Inc.

  公开号：EP0206947A2

  公开（公告）日：1986-12-30

  Choline ester salts are used as drug absorption enhancing agents for orally and rectally administered drugs.

  胆碱酯盐可作为口服和直肠给药的药物吸收促进剂。