(E)-2-(1,3-benzothiazol-2-yl)-3-[4-[2-hydroxyethyl(methyl)amino]phenyl]prop-2-enenitrile

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: (E)-2-(1,3-benzothiazol-2-yl)-3-[4-[2-hydroxyethyl(methyl)amino]phenyl]prop-2-enenitrile
• 化学式: C₁₉H₁₇N₃OS
• 分子量: 335.4
• InChiKey: JQYSXGYOLZCKJX-NTCAYCPXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  88.4
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF
  申请人：East China University of Science and Technology

  公开号：EP3489324A1

  公开（公告）日：2019-05-29

  Provided are a fluorescent probe and a preparation method and the use thereof. The fluorescent probe is sensitive and specific to viscosity response, and can be used for specific fluorescent labeling of proteins, and can also be used for quantification, detection or kinetic study of proteins, and the imaging of cells, tissues and living bodies.

  本发明提供了一种荧光探针及其制备方法和用途。该荧光探针对粘度反应敏感且具有特异性，可用于蛋白质的特异性荧光标记，也可用于蛋白质的定量、检测或动力学研究，以及细胞、组织和活体的成像。
• Fluorescent probe and preparation method and use thereof
  申请人：Fluorescence Diagnosis (shanghai) Biotech Company Ltd.

  公开号：US11209437B2

  公开（公告）日：2021-12-28

  Provided are a fluorescent probe and a preparation process and the use thereof. The fluorescent probe is sensitive and specific to viscosity, and can be used for specific fluorescent labeling of proteins, and can also be used for quantification, detection or kinetic studies of proteins, and the imaging of cells, tissues and living bodies.

  本发明提供了一种荧光探针及其制备工艺和用途。该荧光探针对粘度具有敏感性和特异性，可用于蛋白质的特异性荧光标记，也可用于蛋白质的定量、检测或动力学研究，以及细胞、组织和活体的成像。
• [EN] NUCLEIC ACID APTAMER MOLECULE<br/>[FR] MOLÉCULE D'ACIDE NUCLÉIQUE APTAMÈRE<br/>[ZH] 核酸适配体分子
  申请人：UNIV EAST CHINA SCIENCE & TECH

  公开号：WO2021057816A1

  公开（公告）日：2021-04-01

  一种适配体核酸分子，包含该适配体和荧光团小分子的复合物，该适配体核酸分子用于检测细胞内或者细胞外的RNA、DNA或者其他靶分子的方法，以及包含该适配体的试剂盒。所述适配体可以特异性结合一种荧光团小分子，并显著提高其在合适波长光激发下的荧光强度。
• FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF
  申请人：EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

  公开号：US20200248069A1

  公开（公告）日：2020-08-06

  Provided are a fluorescent probe, a preparation method therefor and a use thereof. The fluorescent probe responds to viscosity sensitively and specifically, can be used for the specific fluorescence labeling of proteins and can also be used in the quantification, detection or kinetic study of proteins and the imaging of cells, tissues and living bodies.
• FLUORESCENT DYE, PREPARATION METHOD AND USES THEREOF
  申请人：FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD.

  公开号：US20220214351A1

  公开（公告）日：2022-07-07

  A fluorescent dye, as well as a preparation method and uses thereof, wherein the fluorescent dye is sensitive and specific to viscosity and has low background fluorescence; it can also be used as a fluorescent activated and lighted probe used for fluorescent labeling, quantification or monitoring of protein, enzymes or nucleic acid.