申请人:——
公开号:US20030003059A1
公开(公告)日:2003-01-02
The present invention relates to oral care compositions which provide a means to deliver actives which are useful in the prevention, treatment and/or management of dental and related tissue conditions, including dental caries, dental cavities, microbial flora, tartar, periodontal and related gum disease. In addition, the present invention may be used in the healthy maintenance of teeth and gums. Further aspects of the present invention are related to the present compositions being useful to whiten teeth and otherwise favorably impact the cosmetic appeal of the teeth and gums of a subject or patient. A further aspect of the present invention is directed to the inclusion of effective amounts of colostrum in dental care compositions for the unexpectedly high efficacy such formulations provide in inhibiting, reducing or otherwise preventing microbial growth, dental caries, plaque, cavities and gum disease, including periodontal disease. The use of colustrum with other enzymes as otherwise described herein represents a particularly preferred embodiment for use in the present invention because of the unexpected antimicrobial activity exhibited by the enzyme combination.
本发明涉及口腔护理组合物,它提供了一种传递活性物质的方法,这些活性物质有助于预防、治疗和/或控制牙齿及相关组织病症,包括龋齿、蛀牙、微生物菌群、牙垢、牙周病和相关牙龈疾病。此外,本发明还可用于牙齿和牙龈的健康维护。本发明的更多方面涉及本发明组合物可用于美白牙齿,并以其他方式对受试者或患者的牙齿和牙龈的外观吸引力产生有利影响。本发明的另一个方面是关于在牙齿护理组合物中加入有效量的牛初乳,因为这种制剂在抑制、减少或以其他方式预防微生物生长、龋齿、牙菌斑、蛀牙和牙龈疾病(包括牙周病)方面具有意想不到的高功效。将牛初乳与其他酶一起使用,如本文所述,是用于本发明的一个特别优选的实施方案,因为酶组合具有意想不到的抗微生物活性。