Isobutyraldehyde, diethylhydrazone

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Isobutyraldehyde, diethylhydrazone
• 英文别名: N-ethyl-N-[(E)-2-methylpropylideneamino]ethanamine
• 化学式: C₈H₁₈N₂
• 分子量: 142.24
• InChiKey: KDMGAIKQJYFJMZ-VQHVLOKHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  15.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING<br/>[FR] COMPOSÉS ET COMPOSITIONS UTILISÉS EN TANT QUE MODULATEURS DE LA SIGNALISATION TLR
  申请人：NEUROPORE THERAPIES INC

  公开号：WO2020198368A1

  公开（公告）日：2020-10-01

  The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.

  本发明公开涉及化合物、包含此类化合物的药物组合物，以及此类化合物在治疗炎症性疾病和与炎症信号传导过程相关的某些神经障碍的方法或药物中的用途，所述神经障碍包括但不限于错误折叠的蛋白质。
• COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING
  申请人：Neuropore Therapies, Inc.

  公开号：US20200308163A1

  公开（公告）日：2020-10-01

  The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.