9-(5-chlorothiophen-2-yl)-3,4,5,6,7,9-hexahydro-2H-cyclopenta[b][1,6]naphthyridine-1,8-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 9-(5-chlorothiophen-2-yl)-3,4,5,6,7,9-hexahydro-2H-cyclopenta[b][1,6]naphthyridine-1,8-dione
• 化学式: C₁₅H₁₃ClN₂O₂S
• 分子量: 320.8
• InChiKey: WFTZOTYJKACQAB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  86.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• DIHYDROPYRIDINE COMPOUNDS AND METHODS OF USE
  申请人：ABBOTT LABORATORIES

  公开号：EP1131322A2

  公开（公告）日：2001-09-12
• [EN] DIHYDROPYRIDINE COMPOUNDS AND METHODS OF USE<br/>[FR] COMPOSES DE DIHYDROPYRIDINE ET LEUR MODE D'UTILISATION
  申请人：ABBOTT LAB

  公开号：WO2000024741A2

  公开（公告）日：2000-05-04

  Compounds having formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
• [EN] DIHYDROPYRIDINE COMPOUNDS AND METHODS OF USE<br/>[FR] COMPOSES DE DIHYDROPYRIDINE ET PROCEDES D'UTILISATION
  申请人：ABBOTT LAB

  公开号：WO2001083480A2

  公开（公告）日：2001-11-08

  Compounds having the formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.