Sodium;3-phenoxazin-10-ylpropane-1-sulfonate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: Sodium;3-phenoxazin-10-ylpropane-1-sulfonate
• 化学式: C15H14NNaO4S
• 分子量: 327.3
• InChiKey: KSCARLWNEMNNIJ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.13
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  78
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Method for the chemiluminescence assay of the activity of peroxidase
  申请人：FUJIREBIO INC.

  公开号：EP0361470A2

  公开（公告）日：1990-04-04

  A method of chemiluminescence assay of the activity of peroxidase is disclosed, which employes (i) luminol or isoluminol as a substrate, (ii) hydrogen peroxide, and (iii) at lease one compound, serving as an enhancer for the activity of peroxidase, selected from the group consisting of wherein R¹ represents a hydroxyl group, an alkali metal salt of hydroxyl group (-OM, where M is an alkali metal), an amino group which may have a substituent, a halogen, an alkyl group having 1 to 4 carbon atoms, which may have a substituent; R² and R³ each represent hydrogen or a halogen; R⁴ and R⁵ each represent hydrogen, an alkyl group having 1 to 4 carbon atoms, which may have a substituent, or an alkoxyl group having 1 to 4 carbon atoms, which may have a substituent; wherein R⁶ represents an alkyl group having 1 to 6 carbon atoms, which may have a substituent, or an alkene group having 2 to 6 carbon atoms, which may have a substituent, R⁷ to R¹⁰ each represent hydrogen, an alkyl group having 1 to 6 carbon atoms, which may have a substituent, or a halogen, X represents oxygen or sulfur, Y represents -CH- or nitrogen, which may be the same or different, and Y′ represents carbon or nitrogen, which may be the same or different.

  本发明公开了一种过氧化物酶活性的化学发光检测方法，该方法采用(i)发光酚或异鲁米诺作为底物，(ii)过氧化氢，和(iii)至少一种化合物作为过氧化物酶活性的增强剂、选自由下列物质组成的组 其中 R¹ 代表羟基、羟基的碱金属盐（-OM，其中 M 为碱金属）、可能具有取代基的氨基、卤素、具有 1 至 4 个碳原子且可能具有取代基的烷基；R² 和 R³ 分别代表氢或卤素；R⁴ 和 R⁵ 分别代表氢、1-4 个碳原子的烷基（可带有取代基）或 1-4 个碳原子的烷氧基（可带有取代基）； 其中 R⁶ 代表具有 1 至 6 个碳原子的烷基，该烷基可能具有取代基，或具有 2 至 6 个碳原子的烯基，该烯基可能具有取代基，R⁷ 至 R¹⁰ 各自代表氢、具有 1 至 6 个碳原子的烷基、X代表氧或硫，Y代表-CH-或氮，它们可以相同或不同，Y′代表碳或氮，它们可以相同或不同。
• US5171668A
  申请人：——

  公开号：US5171668A

  公开（公告）日：1992-12-15
• US8192948B1
  申请人：——

  公开号：US8192948B1

  公开（公告）日：2012-06-05