溴化二乙基甲基[2-[(2-甲基-1-羰基烯丙基)氧代]乙基]铵 | 59836-87-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 溴化二乙基甲基[2-[(2-甲基-1-羰基烯丙基)氧代]乙基]铵
• 中文别名: 二乙基甲基[2-[(2-甲基-1-氧代烯丙基)氧基]乙基]溴化铵
• 英文名称: Diethylmethyl(2-((2-methyl-1-oxoallyl)oxy)ethyl)ammonium bromide
• 英文别名: diethyl-methyl-[2-(2-methylprop-2-enoyloxy)ethyl]azanium;bromide
• CAS: 59836-87-2
• 化学式: C11H22BrNO2
• 分子量: 280.2
• InChiKey: OVPZVYPVKVHQLZ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Antimicrobial compositions and methods
  申请人：Scholz T. Matthew

  公开号：US20050058673A1

  公开（公告）日：2005-03-17

  Antimicrobial compositions, especially those useful when applied topically, particularly to mucosal tissues (i.e., mucous membranes), including a fatty acid ester, fatty ether, or alkoxide derivative thereof. The compositions can also include an enhancer component, a surfactant, a hydrophobic component, and/or a hydrophilic component. Such compositions provide effective topical antimicrobial activity and are accordingly useful in the treatment and/or prevention of conditions that are caused, or aggravated by, microorganisms (including viruses).

  抗微生物组合物，特别是在局部应用时有用的组合物，特别是应用于黏膜组织（即粘膜）的组合物，包括脂肪酸酯，脂肪醚或其烷氧基衍生物。这些组合物还可以包括增效剂成分，表面活性剂，疏水性成分和/或亲水性成分。这些组合物提供有效的局部抗微生物活性，因此在治疗和/或预防由微生物（包括病毒）引起或加重的疾病方面具有用处。
• METHODS OF REDUCING MICROBIAL CONTAMINATION
  申请人：Scholz Matthew T.

  公开号：US20090226541A1

  公开（公告）日：2009-09-10

  Methods of delaying the onset of an infection or preventing an infection caused by a microbial organism in an internal cavity of a subject are provided. Methods of killing or inactivating microorganisms in at least a portion of the urethra of a subject are provided.

  提供了延迟微生物体在主体内部腔引起感染或预防感染的方法。提供了在主体的尿道至少部分区域内杀死或灭活微生物的方法。
• Cationic antiseptic compositions and methods of use
  申请人：Scholz T. Matthew

  公开号：US20060051385A1

  公开（公告）日：2006-03-09

  Antimicrobial compositions, especially those useful when applied topically, particularly to mucosal tissues (i.e., mucous membranes), including a cationic antiseptic such as biguanides and bisbiguanides such as chlorhexidine and its various salts including but not limited to the digluconate, diacetate, dimethosulfate, and dilactate salts; polymeric quaternary ammonium compounds such as polyhexamethylenebiguanide; silver and various silver complexes; small molecule quaternary ammonium compounds such as benzalkoium chloride and alkyl substituted derivatives; di-long chain alkyl (C8-C18) quaternary ammonium compounds; cetylpyridinium halides and their derivatives; benzethonium chloride and its alkyl substituted derivatives; and octenidine. The compositions can also include an enhancer component, a surfactant, a hydrophobic component, and/or a hydrophilic component. Such compositions provide effective topical antimicrobial activity and are accordingly useful in the treatment and/or prevention of conditions that are caused, or aggravated by, microorganisms (including viruses).

  抗微生物组合物，特别是应用于黏膜组织（即黏膜），尤其是局部应用的组合物，包括阳离子抗菌剂，如双胍类和双双胍类，如氯己定及其各种盐，包括但不限于双乙酸盐、二甲硫酸盐和二乳酸盐；聚合物季铵化合物，如聚己亚甲基双胍；银及其各种银络合物；小分子季铵化合物，如苯扎氯铵和烷基取代衍生物；双长链烷基（C8-C18）季铵化合物；十六烷基吡啶卤化物及其衍生物；苯乙铵和其烷基取代衍生物；以及辛甲硫唑。该组合物还可以包括增强剂组分、表面活性剂、疏水性组分和/或亲水性组分。这些组合物提供有效的局部抗微生物活性，因此在治疗和/或预防由微生物（包括病毒）引起或加重的疾病方面非常有用。
• Antiseptic Compositions and Methods of Use
  申请人：3M Innovative Properties Company

  公开号：EP2156738A1

  公开（公告）日：2010-02-24

  Antimicrobial compositions, especially those useful when applied topically to tissue, such as mucosal tissues (i.e., mucous membranes), that include an antimicrobial selected from the group consisting of peroxides, C6-C14 alkyl carboxylic acids, C6-C14 alkyl carboxylate ester carboxylic acids, C8-C22 mono- or polyunsaturated carboxylic acids, and antimicrobial natural oils. The compositions can also include an enhancer component, a surfactant, a hydrophobic component, and/or a hydrophilic component. Such compositions provide effective topical antimicrobial activity and are accordingly useful in the treatment and/or prevention of conditions that are caused, or aggravated by, microorganisms (including viruses).

  抗菌剂组合物，尤其是局部用于组织，如粘膜组织（即粘膜）时有用的组合物，其中包括选自过氧化物、C6-C14 烷基羧酸、C6-C14 烷基羧酸酯羧酸、C8-C22 单不饱和或多不饱和羧酸和抗菌天然油组成的组的抗菌剂。组合物还可以包括增强剂成分、表面活性剂、疏水成分和/或亲水成分。此类组合物具有有效的局部抗菌活性，因此可用于治疗和/或预防由微生物（包括病毒）引起或加重的病症。
• Liquid antiseptic compositions containing iodine and a sugar and/or sugar alcohol
  申请人：Scholz Matthew T.

  公开号：US10052384B2

  公开（公告）日：2018-08-21

  The present invention relates to compositions that contain iodine intended primarily for tissue antisepsis, particularly skin antisepsis.

  本发明涉及主要用于组织防腐，特别是皮肤防腐的含碘组合物。