1,1',1'',1'''-ethane-1,2-diylbisazanediyl-tetrakis-butan-2-ol | 122-24-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,1',1'',1'''-ethane-1,2-diylbisazanediyl-tetrakis-butan-2-ol
• 英文别名: tetrakis-N-(2-hydroxy-butyl)-ethane-1,2-diamine；N,N,N',N',-Tetrakis(2-hydroxybutyl) ethylenediamine；N,N,N',N'-tetra(2-hydroxybutyl)ethylenediamine；1-[2-[Bis(2-hydroxybutyl)amino]ethyl-(2-hydroxybutyl)amino]butan-2-ol
• CAS: 122-24-7
• 化学式: C₁₈H₄₀N₂O₄
• 分子量: 348.527
• InChiKey: RLRNFLABYNJCLA-UHFFFAOYSA-N

物化性质

• 沸点：
  426.9±12.0 °C(Predicted)
• 密度：
  1.050±0.06 g/cm3(Predicted)
• 熔点：
  277 °C(Solv: ethyl acetate (141-78-6))

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  24
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  87.4
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  1,1',1'',1'''-ethane-1,2-diylbisazanediyl-tetrakis-butan-2-ol 、 苯硼酸 生成 4,8,4',8'-tetraethyl-2,2'-diphenyl-6,6'-ethane-1,2-diyl-bis-[1,3,6,2]dioxazaborocane
  参考文献：
  名称：

  Psarras,T.G. et al., Justus Liebigs Annalen der Chemie, 1962, vol. 655, p. 48 - 54

  摘要：

  DOI：

文献信息

• WATER-STABLE COMPOUNDS, CATALYSTS AND CATALYSED REACTIONS
  申请人：Tulloch Arran Alexander Dickon

  公开号：US20100292449A1

  公开（公告）日：2010-11-18

  The invention provides a method of carrying out a Lewis-acid catalysed organic reaction in the presence of a Lewis acid catalyst comprising a metal-organic compound having the following formula: M(HO(CR 1 R 2 )z)a(O(CR 1 R 2 )z)bY—(CR 3 R 4 )χ-Y((CR 1 R 2 )zO)c((CR 1 R 2 )zOH)d.nR 5 OH (Formula I) in which: M is a metal atom, preferably titanium, zirconium, hafnium or iron (III) Y is selected from P and N, but Ss very preferably N; each R 1 , R 2 , R 3 and R 4 is independently selected from H, alkyl, aryl, substituted alkyl or substituted aryl, R 5 is hydrogen, an alkyl group, a hydroxy-functionalised alkyl group, a polyoxyalkylmoiety, R 6 O or R 7 COO where R 6 and R 7 may each represent H, alkyl, aryl or alkyl-aryl; d and a are each O or 1, b and c are each 1 or 2, b+c=the valency of M, a+b+c+d=4, each z is independently 1, 2, 3 or 4; x represents the least number of C atoms between the Y atoms and is 2 or 3 and n is a number in the range from 0 to 4. The metal-organic compound forms a stable hydrate in water which retains Lewis-acid catalytic properties.

  本发明提供了一种在存在Lewis酸催化剂的情况下进行Lewis酸催化的有机反应的方法，该Lewis酸催化剂包括具有以下公式的金属有机化合物：M(HO(CR1R2)z)a(O(CR1R2)z)bY—(CR3R4)χ-Y((CR1R2)zO)c((CR1R2)zOH)d.nR5OH（公式I），其中：M是金属原子，优选钛、锆、铪或铁(III)；Y选自P和N，但非常优选N；每个R1、R2、R3和R4独立地选自H、烷基、芳基、取代烷基或取代芳基；R5是氢、烷基、羟基功能化的烷基、聚氧烷基部分、R6O或R7COO，其中R6和R7各自可以代表H、烷基、芳基或烷基芳基；d和a各自是O或1，b和c各自是1或2，b+c等于M的价，a+b+c+d=4，每个z独立地是1、2、3或4；x代表Y原子之间最少的C原子数，是2或3，n是0到4之间的数。金属有机化合物在水中形成稳定的含水物，保留了Lewis酸催化性质。
• Aqueous ink composition
  申请人：SAKURA COLOR PRODUCTS CORPORATION

  公开号：EP0030389A1

  公开（公告）日：1981-06-17

  The present invention provides an aqueous ink composition comprising: (a) at least one N,N,N',N'-tetrakis-(2-hydroxyalkyl)-ethylenediamine represented by the formula wherein Ri, R2, R3 and R4 each represent a group of the formula and mav be the same, or at least one of these groups may be different from the others, n being zero or an integer of 1 to 3, (b) a dye, (c) a hygroscopic water-soluble organic solvent, and (d) water. The aqueous ink composition of the invention is used for fountain pens, porous point pens, roller pens or like writing implements, and has an improved storage stability, continuous writability and solution stability.

  本发明提供了一种水性油墨组合物，其中包括 (a) 至少一种由式表示的 N,N,N',N'-四-(2-羟基烷基)-乙二胺 其中 Ri、R2、R3 和 R4 各代表一个式中的基团 其中 n 为零或 1 至 3 的整数、 (b) 染料 (c) 吸湿性水溶性有机溶剂，和 (d) 水。 本发明的水性墨水组合物可用于钢笔、多孔点钢笔、圆珠笔或类似书写工具，并具有更好的储存稳定性、连续书写性和溶液稳定性。
• Macrophage stimulation by homolog or analog of quadrol
  申请人：The University of Akron

  公开号：EP0372123A1

  公开（公告）日：1990-06-13

  Quadrol and homologs and analogs thereof have been found to stimulate macrophage activity in warm blooded animals. As a consequence, these compounds may be used to combat bacterial infection, remove degenerated tissue, and promote new tissue growth. Quadrol or a homolog or analog thereof may be applied topically, e.g., as the active agent in a wound dressing. The active compounds may be represented by the formula (I) wherein R₁ and R₂ are substituted alkyl (C₂-­C₆) in which the substituents include one or more hydroxyl groups attached to carbon atoms other than the alpha carbon atom, R₃ and R₄ are alkyl or substituted alkyl (C₁-C₆), and n=2 to about 6. Preferably R₁ through R₄ are the same and are 2-hydroxyalkyl.

  研究发现，Quadrol 及其同源物和类似物可刺激温血动物体内巨噬细胞的活性。因此，这些化合物可用于对抗细菌感染、清除退化组织和促进新组织生长。Quadrol 或其同源物或类似物可局部使用，例如作为伤口敷料中的活性剂。活性化合物可由式 (I) 表示 其中 R₁ 和 R₂ 是取代的烷基 (C₂-C₆)，其中取代基包括一个或多个连接到除α 碳原子以外的碳原子上的羟基，R₃ 和 R₄ 是烷基或取代的烷基 (C₁-C₆)，且 n=2 至约 6。R₁ 至 R₄ 最好是相同的 2-羟基烷基。
• Method of preparing oligomeric polyol compositions
  申请人：Presidium USA, Inc

  公开号：US11066512B2

  公开（公告）日：2021-07-20

  There is provided an oligomeric polyol composition having (a) an oligomeric network containing residues of at least one polyhydroxylated aromatic compound and residues of at least one polyol having at least three hydroxyl groups; and (b) a plurality of peripheral groups having one or more pendant hydroxyl groups bound to the oligomeric network by a plurality of linking units. The residues of the polyol may optionally contain one or more oxygen ether groups, one or more amino ether groups, or both of one or more oxygen ether groups and one or more amino ether groups. Reaction of the oligomeric polyols with isocyanate monomers affords a new class of polyurethanes having superior heat and water resistance. The new polyurethanes exhibit lower peak exotherms, typically less than 250° F. during in-mold polymerization. Articles prepared from polyurethanes incorporating such oligomeric polyol compositions exhibit flexural strengths and moduli in excess of 10,000 psi and 400,000 psi respectively, and outstanding green strength.

  本发明提供了一种低聚多元醇组合物，该组合物具有：(a) 低聚网络，其中包含至少一种多羟基芳香族化合物的残留物和至少一种具有至少三个羟基的多元醇的残留物；以及(b) 多个外围基团，这些外围基团具有一个或多个通过多个连接单元与低聚网络结合的垂羟基。多元醇的残基可选择含有一个或多个氧醚基团、一个或多个氨基醚基团，或同时含有一个或多个氧醚基团和一个或多个氨基醚基团。低聚多元醇与异氰酸酯单体反应可产生一类新型聚氨酯，具有优异的耐热性和耐水性。这种新型聚氨酯的放热峰值较低，模内聚合时通常低于 250°F。用含有此类低聚多元醇组合物的聚氨酯制备的物品，其抗弯强度和模量分别超过 10,000 psi 和 400,000 psi，并且具有出色的绿色强度。
• Polyurethanes prepared from oligomeric polyol compositions and polyisocyanates
  申请人：Presidium USA, Inc

  公开号：US11072679B2

  公开（公告）日：2021-07-27

  There is provided an oligomeric polyol composition having (a) an oligomeric network containing residues of at least one polyhydroxylated aromatic compound and residues of at least one polyol having at least three hydroxyl groups; and (b) a plurality of peripheral groups having one or more pendant hydroxyl groups bound to the oligomeric network by a plurality of linking units. The residues of the polyol may optionally contain one or more oxygen ether groups, one or more amino ether groups, or both of one or more oxygen ether groups and one or more amino ether groups. Reaction of the oligomeric polyols with isocyanate monomers affords a new class of polyurethanes having superior heat and water resistance. The new polyurethanes exhibit lower peak exotherms, typically less than 250° F. during in-mold polymerization. Articles prepared from polyurethanes incorporating such oligomeric polyol compositions exhibit flexural strengths and moduli in excess of 10,000 psi and 400,000 psi respectively, and outstanding green strength.

  本发明提供了一种低聚多元醇组合物，该组合物具有：(a) 低聚网络，其中包含至少一种多羟基芳香族化合物的残留物和至少一种具有至少三个羟基的多元醇的残留物；以及(b) 多个外围基团，这些外围基团具有一个或多个通过多个连接单元与低聚网络结合的垂羟基。多元醇的残基可选择含有一个或多个氧醚基团、一个或多个氨基醚基团，或同时含有一个或多个氧醚基团和一个或多个氨基醚基团。低聚多元醇与异氰酸酯单体反应可产生一类新型聚氨酯，具有优异的耐热性和耐水性。这种新型聚氨酯的放热峰值较低，模内聚合时通常低于 250°F。用含有此类低聚多元醇组合物的聚氨酯制备的物品，其抗弯强度和模量分别超过 10,000 psi 和 400,000 psi，并且具有出色的绿色强度。