2-(5-己基噻吩-2-基)乙炔基-三甲基硅烷 | 880491-25-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 中文名称: 2-(5-己基噻吩-2-基)乙炔基-三甲基硅烷
• 英文名称: 2-hexyl-5-trimethylsilylethynylthiophene
• 英文别名: 2-trimethylsilylethynyl-5-hexylthiophene；[(5-hexylthiophen-2-yl)ethynyl]trimethylsilane；[2-(5-hexylthiophen-2-yl)ethynyl]trimethylsilane；[(5-Hexylthiophen-2-yl)ethynyl](trimethyl)silane；2-(5-hexylthiophen-2-yl)ethynyl-trimethylsilane
• CAS: 880491-25-8
• 化学式: C₁₅H₂₄SSi
• 分子量: 264.507
• InChiKey: OKCOJZHJHWSPNA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  28.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-(5-己基噻吩-2-基)乙炔基-三甲基硅烷 在 氢氧化钾 、 copper(l) iodide 、 四(三苯基膦)钯 、 三乙胺 作用下， 以 四氢呋喃 为溶剂， 生成 5-hexyl-2-thienylethynyl-2,2'-bithiophene
  参考文献：
  名称：

  Synthesis and Solution-processed Field Effect Transistors of Liquid Crystalline Oligothiophenes

  摘要：

  利用一种新合成的四噻吩基液晶分子溶液，通过湿法工艺制造出了一种有机场效应晶体管（OFET），其迁移率为 0.015 cm2 V-1 s-1，导通/关断比为 104，与低聚噻吩干法场效应晶体管的迁移率和关断比一样高。

  DOI：

  10.1246/cl.2007.708
• 作为产物：
  描述：

  2-正己基噻吩 在 bis-triphenylphosphine-palladium(II) chloride 、 N-溴代丁二酰亚胺(NBS) 、 copper(l) iodide 、 二异丙胺 作用下， 以 氯仿 、 溶剂黄146 为溶剂， 反应 14.0h， 生成 2-(5-己基噻吩-2-基)乙炔基-三甲基硅烷
  参考文献：
  名称：

  Small asymmetric anthracene–thiophene compounds as organic thin-film transistors

  摘要：

  Anthracene and thiophene compounds are promising materials for OTFTs. We report here, the synthesis, as well as the physical, thermal, and optoelectronic properties of alkyl-substituted asymmetric anthracene-thiophene compounds connected by a bridged triple bond. The target molecules were synthesized using 2-bromoanthracene as the starting material, and the proceeding reactions included alkylation, bromination, and the Sonogashira coupling reaction. The synthesized compounds were both thermally and electrochemically stable. Among the synthesized compounds, HTEA (7a) and DTEA (7b) showed mobility and on/off ratio values of 1.3x10(-1) cm(2)/V s, 2.6 x 10(6) and 2.0x10(-2) cm(2)/V s, 1.0x10(6), respectively. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.07.041

文献信息

• INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER
  申请人：Pauls Heinz W.

  公开号：US20100105900A1

  公开（公告）日：2010-04-29

  A CPT inhibitor compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating a subject having cancer comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.

  一种CPT抑制剂化合物由结构式(I)或其药学上可接受的盐所代表：或其药学上可接受的盐。一种制药组合物包括由结构式(I)或其药学上可接受的盐所代表的化合物。一种治疗患有癌症的受试者的方法包括向该受试者施用由结构式(I)或其药学上可接受的盐所代表的治疗有效量的化合物。
• Inhibitors of carnitine palmitoyltransferase and treating cancer
  申请人：Pauls Heinz W.

  公开号：US08410150B2

  公开（公告）日：2013-04-02

  A CPT inhibitor compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating a subject having cancer comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.

  一种CPT抑制剂化合物由结构式（I）或其药学上可接受的盐表示：或其药学上可接受的盐。一种制药组合物包括一种由结构式（I）或其药学上可接受的盐表示的化合物。一种治疗癌症患者的方法包括向患者施用一种由结构式（I）或其药学上可接受的盐表示的治疗有效量的化合物。
• 포피린계 유도체, 이를 포함하는 유기박막 트랜지스터 및 이를 포함하는 광전소자
  申请人：Korea University Research and Business Foundation 고려대학교 산학협력단(220040170680) BRN ▼209-82-08298

  公开号：KR101484819B1

  公开（公告）日：2015-01-20

  본 발명은 포피린계 유도체, 이를 포함하는 유기박막 트랜지스터 및 이를 포함하는 광전 소자에 관한 것으로 용매에 대한 우수한 용해도 및 개선된 내산화성을 갖고 나아가 우수한 열적 안정성 및 높은 필드 이펙트 이동도와 같은 전기적 특성을 갖는다.

  这项发明涉及吡咯烷衍生物，以及包含它们的有机薄膜晶体管和包含它们的光电器件，具有对溶剂良好的溶解度和改进的耐酸性，进一步具有优异的热稳定性和高场效应迁移率等电学特性。
• Large Area Liquid Crystal Monodomain Field-Effect Transistors
  作者：Albert J. J. M. van Breemen、Peter T. Herwig、Ceciel H. T. Chlon、Jörgen Sweelssen、Herman F. M. Schoo、Sepas Setayesh、Willie M. Hardeman、Christian A. Martin、Dago M. de Leeuw、Josué J. P. Valeton、Cees W. M. Bastiaansen、Dirk J. Broer、Andreea R. Popa-Merticaru、Stefan C. J. Meskers

  DOI：10.1021/ja055337l

  日期：2006.2.1

  Butyl, hexyl, and decyl derivatives of the liquid-crystal line organic semiconductor 5,5 double prime -bis(5alkyl-2-thienylethynyl)-2,2':5',2double prime -terthiophene were synthesized and studied with respect to their structural, optical, and electrical properties. By means of an optimized thermal annealing scheme the hexyl and decyl compounds could be processed into self-assembled monodomain films of up to 150 mm in diameter. These were investigated with X-ray diffractometry, which revealed a clearly single-crystalline monoclinic morphology with lamellae parallel to the substrate. Within the lamellae the molecules were found to arrange with a tilt of about 50 degrees with the rubbing direction of the polyimide alignment layer. The resulting, close side-to-side packing was confirmed by measurements of the UV/vis absorption, which showed a dichroic ratio of 19 and indicated H-aggregation. AFM analyses revealed self-affinity in the surface roughness of the monodomain. The compounds showed bipolar charge transport in TOF measurements, with hole mobilities reaching up to 0.02 cm(2)/Vs and maximum electron mobilities around 0.002 cm(2)/Vs. The hexyl derivative was processed into large-area monodomain top-gate field-effect transistors, which were stable for months and showed anisotropic hole mobilities of up to 0.02 cm(2)/Vs. Compared to multidomain bottom-gate transistors the monodomain formation allowed for a mobility increase by 1 order of magnitude.
• Synthesis, characterization and DFT calculations of new ethynyl-bridged C60 derivatives
  作者：Simon Rondeau-Gagné、Carles Curutchet、François Grenier、Gregory D. Scholes、Jean-François Morin

  DOI：10.1016/j.tet.2010.03.092

  日期：2010.6

  A new series of soluble C-60 derivatives for organic electronic application has been synthesized by ethynylation reaction using different electron-donating and electron-withdrawing groups of varying length. (C) 2010 Elsevier Ltd. All rights reserved.