1-methyl-3-(2-(piperidin-1-yl)ethyl)-1H-imidazol-3-ium-chloride | 1048677-33-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-methyl-3-(2-(piperidin-1-yl)ethyl)-1H-imidazol-3-ium-chloride
• 英文别名: 1-(2'-piperid-1'-yl-ethyl)-3-methylimidazolium chloride；[MimPD]Cl；1-[2-(3-Methylimidazol-3-ium-1-yl)ethyl]piperidine;chloride；1-[2-(3-methylimidazol-3-ium-1-yl)ethyl]piperidine;chloride
• CAS: 1048677-33-3
• 化学式: C₁₁H₂₀N₃*Cl
• 分子量: 229.753
• InChiKey: SWWDRVKOMCGNNZ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  12
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-methyl-3-(2-(piperidin-1-yl)ethyl)-1H-imidazol-3-ium-chloride 在 氟硼酸钠 作用下， 以 二氯甲烷 、 水 为溶剂， 生成 1-(2'-piperid-1'-yl-ethyl)-3-methylimidazolium tetrafluoroborate
  参考文献：
  名称：

  An ionic phosphine-ligated rhodium(III) complex as the efficient and recyclable catalyst for biphasic hydroformylation of 1-octene

  摘要：

  A novel ionic complex with insensitivity to moisture and air, bis-[1-butyl-2-diphenylphosphanyl-3-methylimidazolium]tetrachloridorhodium(III) hexafluorophosphate (1A), has been synthesized and fully characterized. The single-crystal X-ray diffraction analysis shows that 1A is composed of the Rh(III)-complex cation and the counter-anion of PF6-. The complex cation has highly symmetrical Rh-III-centered octahedron geometry with four Cl atoms in the equatorial plane and two imidazolium-substituted phosphine ligands in the axial position. The catalytic performance of 1A, which could be tailored by the ligands and the solvents, was investigated toward the biphasic hydroformylation of 1-octene. It was found that the presence of the hemilabile hybrid P,N-ligand of 3 (1-(2'-piperid-1'-yl-ethyl)-2-diphenylphosphino-3-methylimidazolium hexafluorophosphate), as a kind of ligand-functionalized ionic liquids (ILs), could dramatically spur the catalytic activity of 1A. The use of the RTIL of [PEmim]BF4 (1-(2'-piperid-1'-yl-ethyl)-3-methylimidazolium tetrafluoroborate) as the solvent not only fulfilled the efficient biphasic hydroformylation of 1-octene, but also guaranteed the successful recovery and recycling of the ionic compositions of 1A and 3. (c) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2013.07.004
• 作为产物：
  描述：

  N-甲基咪唑 、 1-(2-氯乙基)哌啶盐酸盐 在 potassium hydroxide 作用下， 以 乙醇 、 水 为溶剂， 反应 72.0h， 生成 1-methyl-3-(2-(piperidin-1-yl)ethyl)-1H-imidazol-3-ium-chloride
  参考文献：
  名称：

  基于多金属氧酸盐的氨基官能化离子固体 催化剂 导致高效的异构 环氧化 的 烯烃与H 2 O 2

  摘要：

  质子交换和阴离子交换氨基连接制备的基于多金属氧酸盐（POM）的离子杂化纳米球 离子液体 阳离子 Keggin POM阴离子已被证明是高效异质的 催化剂 用于环氧化 烯烃H 2 O 2，具有回收方便，稳定重用，制备简单，组成灵活的优点。

  DOI：

  10.1039/c1gc15302a
• 作为试剂：
  描述：

  反式硝基苯乙烯 、 乙酰乙酸甲酯 在 1-methyl-3-(2-(piperidin-1-yl)ethyl)-1H-imidazol-3-ium-chloride 作用下， 以 neat (no solvent) 为溶剂， 反应 0.5h， 以83%的产率得到2-乙酰基-4-硝基-3-苯基丁酸甲酯
  参考文献：
  名称：

  Basic-functionalized recyclable ionic liquid catalyst: A solvent-free approach for Michael addition of 1,3-dicarbonyl compounds to nitroalkenes under ultrasound irradiation

  摘要：

  A task-specific ionic liquid (TSIL) has been introduced as a recyclable catalyst in Michael addition. A series of nitroalkenes and various C-based nucleophiles were reacted in the presence of 30 mol% of recyclable basic-functionalized ionic liquid. Good to excellent yields were obtained in 30 min under ultrasound irradiation. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ultsonch.2012.11.002