3-amino-1-[4-(diethylamino)phenyl]thiourea | 102339-01-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 3-amino-1-[4-(diethylamino)phenyl]thiourea
• 英文别名: Semicarbazide, 4-(p-diethylaminophenyl)-3-thio-；1-amino-3-[4-(diethylamino)phenyl]thiourea
• CAS: 102339-01-5
• 化学式: C₁₁H₁₈N₄S
• 分子量: 238.357
• InChiKey: ZSKYZZITPHXHEB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  85.4
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-amino-1-[4-(diethylamino)phenyl]thiourea 、 9-蒽甲醛 以 正丁醇 为溶剂， 反应 2.0h， 以92%的产率得到3-[(anthracen-9-ylmethylidene)amino]-1-[4-(diethylamino)phenyl]thiourea
  参考文献：
  名称：

  Thiosemicarbazones as effective fluorescent sensors for cations and anions

  摘要：

  Series of anthracene-containing chemosensors was synthesized by the reaction of 4-R-thiosemicarbazides with aromatic aldehydes. Spectral studies showed their high sensory activity with respect to a group of cations and anions like Hg2+, F-, CN-, AcO- etc.

  DOI：

  10.1134/s1070363212090137
• 作为产物：
  描述：

  肼基二硫代甲酸甲酯 、 N,N-二乙基对苯二胺 以87%的产率得到3-amino-1-[4-(diethylamino)phenyl]thiourea
  参考文献：
  名称：

  Thiosemicarbazones as effective fluorescent sensors for cations and anions

  摘要：

  Series of anthracene-containing chemosensors was synthesized by the reaction of 4-R-thiosemicarbazides with aromatic aldehydes. Spectral studies showed their high sensory activity with respect to a group of cations and anions like Hg2+, F-, CN-, AcO- etc.

  DOI：

  10.1134/s1070363212090137

文献信息

• Thiosemicarbazones as effective fluorescent sensors for cations and anions
  作者：I. E. Tolpygin

  DOI：10.1134/s1070363212090137

  日期：2012.9

  Series of anthracene-containing chemosensors was synthesized by the reaction of 4-R-thiosemicarbazides with aromatic aldehydes. Spectral studies showed their high sensory activity with respect to a group of cations and anions like Hg2+, F-, CN-, AcO- etc.