2-(二甲氨基)-2-甲基丙烷-1-醇盐酸 | 10026-98-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 2-(二甲氨基)-2-甲基丙烷-1-醇盐酸
• 英文名称: 2-dimethylamino-2-methyl-propan-1-ol; hydrochloride
• 英文别名: 2-Dimethylamino-2-methyl-propan-1-ol; Hydrochlorid；2-(Dimethylamino)-2-methylpropan-1-ol;hydron;chloride；2-(dimethylamino)-2-methylpropan-1-ol;hydron;chloride
• CAS: 10026-98-9
• 化学式: C₆H₁₅NO*ClH
• 分子量: 153.652
• InChiKey: QVNXEWQCNPSJLG-UHFFFAOYSA-N

物化性质

• 熔点：
  252-253 °C (decomp)

计算性质

• 辛醇/水分配系数(LogP)：
  0.74
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  23.5
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2922199090

反应信息

• 作为反应物：
  描述：

  2-(二甲氨基)-2-甲基丙烷-1-醇盐酸 在 吡啶 、 palladium on activated charcoal 、 乙醇 、 氯仿 、 苯 作用下， 生成 4-amino-benzoic acid-(β-dimethylamino-isobutyl ester)
  参考文献：
  名称：

  Sequential combination methods for data clustering analysis

  摘要：

  This paper proposes the use of more than one clustering method to improve clustering performance. Clustering is an optimization procedure based on a specific clustering criterion. Clustering combination can be regarded as a technique that constructs and processes multiple clustering criteria. Since the global and local clustering criteria are complementary rather than competitive, combining these two types of clustering criteria may enhance the clustering performance. In our past work, a multi-objective programming based simultaneous clustering combination algorithm has been proposed, which incorporates multiple criteria into an objective function by a weighting method, and solves this problem with constrained nonlinear optimization programming. But this algorithm has high computational complexity. Here a sequential combination approach is investigated, which first uses the global criterion based clustering to produce an initial result, then uses the local criterion based information to improve the initial result with a probabilistic relaxation algorithm or linear additive model. Compared with the simultaneous combination method, sequential combination has low computational complexity. Results on some simulated data and standard test data are reported. It appears that clustering performance improvement can be achieved at low cost through sequential combination.

  DOI：

  10.1007/bf02962204

文献信息

• Oxime ether derivatives, a new class of nonsteroidal antiinflammatory compounds
  作者：Jan Van Dijk、Jan M. A. Zwagemakers

  DOI：10.1021/jm00219a018

  日期：1977.9

  pronounced antiinflammatory activity in the carrageenan-induced edema test in the rat. The activity was limited mainly to derivatives of p-haloacetophenone oxime and of p-halobenzaldehyde oxime. Nevertheless, the hydroxyethyl and carboxyalkyl groups may be converted into many derivatives with maintenance of activity. Some structure-activity relationships are in contrast to those of the well-known antiinflammatory

  在角叉菜胶诱发的大鼠水肿试验中，发现一系列新的芳香族肟的2-羟乙基和羧烷基醚具有明显的抗炎活性。活性主要限于对卤代苯乙酮肟和对卤代苯甲醛肟的衍生物。然而，在保持活性的情况下，羟乙基和羧烷基可被转化成许多衍生物。一些结构-活性关系与众所周知的抗炎性芳酸的相反。活性限于E立体异构体。选择2-（二甲基氨基）乙基（E）-[[（（对氯-α-甲基亚苄基）-氨基[氧]]乙酸盐（36，INN名称为Cloximate）的盐酸盐用于临床评估。第一结果与药理学前景相符。
• Wood treatment solutions containing fungicides and tertiary alkanolamines and related methods, wood products and composition for protection against fungal organisms
  申请人：KOP-COAT, INC.

  公开号：US11432546B2

  公开（公告）日：2022-09-06

  The present invention provides a solution and related composition of matter and methods which synergistically improves a fungicide's effectiveness in resisting undesired fungal growth. The invention also provides wood and wood products which have been treated with the solution, method or compound.

  本发明提供了一种溶液和相关物质组合物及方法，可协同提高杀真菌剂抵抗不希望的真菌生长的效果。本发明还提供了经该溶液、方法或化合物处理过的木材和木制品。
• HARD SURFACE CLEANERS COMPRISING LOW VOC, LOW ODOR ALKANOLAMINES
  申请人：Dow Global Technologies LLC

  公开号：EP2640816A1

  公开（公告）日：2013-09-25
• Hard Surface Cleaners Comprising Low VOC, Low Odor Alkanolamines
  申请人：Busby Molly I.

  公开号：US20130196893A1

  公开（公告）日：2013-08-01

  Hard surface cleaning compositions comprise: A. Surfactant, e.g., a nonionic ethoxylated alcohol; B. Solvent, e.g., propyleneglycol n-butyl ether; C. Low VOC, low odor, alkanolamine selected from the group consisting of tris(hydroxymethyl)amino methane; 2-amino-2-methyl-1,3-propanediol; 2-amino-2-ethyl-1,3-propanediol; 2-amino-2-methyl-1-propanol; N,N-dimethylamino-2-methyl-1-propanol; and 3-amino-4-octanol; D. Water, and E. Optionally, one or more of an alkaline agent, builder, fragrance, preservative, biocide, colorant, dye and rheology modifier.
• WOOD TREATMENT SOLUTIONS CONTAINING FUNGICIDES AND TERTIARY ALKANOLAMINES AND RELATED METHODS, WOOD PRODUCTS AND COMPOSITION FOR PROTECTION AGAINST FUNGAL ORGANISMS
  申请人：KOP-COAT, INC.

  公开号：US20200107543A1

  公开（公告）日：2020-04-09

  The present invention provides a solution and related composition of matter and methods which synergistically improves a fungicide's effectiveness in resisting undesired fungal growth. The invention also provides wood and wood products which have been treated with the solution, method or compound.