3,4-dimethyl-benzo[h]chromen-2-one | 92724-34-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并吡喃类
• 英文名称: 3,4-dimethyl-benzo[h]chromen-2-one
• 英文别名: 3,4-Dimethyl-benzo[h]chromen-2-on；3,4-Dimethyl-naphtho<1,2-b>pyranon-(1)；3,4-Dimethyl-naphtho<1,2-b>pyranon-(2)；3',4'-Dimethyl-1,2-naphtho-α-pyron；3,4-Dimethylbenzo[h]chromen-2-one
• CAS: 92724-34-0
• 化学式: C₁₅H₁₂O₂
• 分子量: 224.259
• InChiKey: KHDOMBNECPBWAY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3,4-dimethyl-benzo[h]chromen-2-one 在 盐酸 、 ammonium hydroxide 、 高氯酸 、 乙醚 作用下， 生成 3'-methyl-2'-phenyl-spiro[benzo[f]chromene-3,4'-benzo[h]chromene]
  参考文献：
  名称：

  Heilbron et al., Journal of the Chemical Society, 1933, p. 430,432

  摘要：

  DOI：
• 作为产物：
  描述：

  2-甲基乙酰乙酸乙酯 、 萘酚 在 硫酸 作用下， 生成 3,4-dimethyl-benzo[h]chromen-2-one
  参考文献：
  名称：

  Banerjee, Journal of the Indian Chemical Society, 1931, vol. 8, p. 777,781

  摘要：

  DOI：

文献信息

• Process for production of vinyl chloride polymer
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0172427A2

  公开（公告）日：1986-02-26

  This process is a process for production of a vinyl chloride polymer by suspension polymerization or emulsion polymerization of vinyl chloride monomer or a mixture of vinyl chloride monomer with a vinyl monomer copolymerizable with said vinyl chloride monomer in an aqueous medium, characterized in that the polymerization is carried out in a polymerizer, the inner wall surface and portions of the auxiliary equipment thereof which may come into contact with the monomer during polymerization being previously coated with a scaling preventive comprising at least one selected from dyes, pigments and aromatic or heterocyclic compounds having at least 5 conjugated π bonds, while controlling the chloride ion concentration in the reaction mixture to not higher than 100 ppm. According to said process, scaling onto the inner wall surface of a polymerizer, etc. during polymerization can be prevented effectively and surely.

  该工艺是通过氯乙烯单体或氯乙烯单体与可与所述氯乙烯单体共聚的乙烯基单体混合物在水介质中进行悬浮聚合或乳液聚合来生产氯乙烯聚合物的工艺，其特征在于聚合是在聚合器中进行的、内壁表面及其辅助设备中可能在聚合过程中与单体接触的部分事先涂上一层防垢剂，该防垢剂至少包括一种选自染料、颜料和至少有 5 个共轭 π 键的芳香族或杂环化合物的防垢剂，同时控制反应混合物中的氯离子浓度不高于 100 ppm。根据上述工艺，可有效、可靠地防止聚合过程中聚合器等内壁表面结垢。
• Chakravarti, Journal of the Indian Chemical Society, 1931, vol. 8, p. 407
  作者：Chakravarti

  DOI：——

  日期：——
• A solvent-free synthesis of coumarins using a Wells–Dawson heteropolyacid as catalyst
  作者：G.P. Romanelli、D. Bennardi、D.M. Ruiz、G. Baronetti、H.J. Thomas、J.C. Autino

  DOI：10.1016/j.tetlet.2004.09.183

  日期：2004.11

  Substituted coumarins are synthesized from phenols and beta-ketoesters by the Pechmann reaction, using a Wells-Dawson heteropolyacid (H(6)P(2)W(18)O(62)(.)24H(2)O) as catalyst by a solvent-free procedure. This one requires low reaction times, 130degreesC temperature and as little as 1 mol% of Wells-Dawson acid, obtaining good to excellent yields of coumarins. The catalyst showed to be reusable with no differences in the yields. The results are compared with those of the reactions performed in toluene solution. The presented synthetic procedure is a convenient, clean and fast alternative for synthesizing 4-substituted coumarins (17 examples). (C) 2004 Elsevier Ltd. All rights reserved.
• CCCXXX.—Hydroxy-carbonyl compounds. Part V. The preparation of coumarins and 1 : 4-pyrones from phenol, p-cresol, quinol, and α-naphthol
  作者：Alexander Robertson、William F. Sandrock、Catherine B. Hendry

  DOI：10.1039/jr9310002426

  日期：——
• US4757124A
  申请人：——

  公开号：US4757124A

  公开（公告）日：1988-07-12