2-octylnaphthalen-1-ol | 61736-06-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-octylnaphthalen-1-ol
• CAS: 61736-06-9
• 化学式: C₁₈H₂₄O
• 分子量: 256.388
• InChiKey: BUTTVSKEGFYXNY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  正辛醛 、 萘酚 在 [(C₆H₆)(PCy₃)(CO)RuH]⁺*BF₄⁻ 、 异丙醇 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 12.0h， 以69%的产率得到2-octylnaphthalen-1-ol
  参考文献：
  名称：

  钌催化苯酚与醛的脱水 C-H 偶联合成 2-烷基苯酚、苯并呋喃和呫吨衍生物的实验和计算研究

  摘要：

  阳离子Ru-H配合物[(C 6 H 6 )(PCy 3 )(CO)RuH] + BF 4 - ( 1 )被发现是酚类和醛类脱水C-H偶联反应生成的有效催化剂2-烷基苯酚产品。酚类与支链醛的偶联反应选择性地形成1,1-二取代苯并呋喃，而与水杨醛的偶联反应产生呫吨衍生物。从 3-甲氧基苯酚与苯甲醛和 2-丙醇/2-丙醇-d 8 ( k H / k D ) 的偶联反应中观察到正常的氘同位素效应= 2.3 ± 0.3)。在 3-甲氧基苯酚与 4-甲氧基苯甲醛 (C(3) 1.021(3)) 偶联反应的烷基化产物的苄基碳以及与4-三氟苯甲醛 (C(2) 1.017(3)、C(3) 1.011(2))。来自 3-甲氧基苯酚与对位取代苯甲醛p -XC 6 H 4 CHO (X = OMe, Me, H, F, Cl, CF 3 ) 的偶联反应的 Hammett 图显示了 V 形线性斜率。通过 NMR 从1

  DOI：

  10.1021/jacs.1c06887

文献信息

• [EN] VINYLOGOUS 4H-PYRONES AND THEIR USE IN PROMOTING PLANT GROWTH<br/>[FR] 4H-PYRONES CONTENANT UN VINYLE ET LEUR UTILISATION POUR FAVORISER LA CROISSANCE DE PLANTES
  申请人：BOTAN GARDENS AND PARKS AUTHOR

  公开号：WO2005061515A1

  公开（公告）日：2005-07-07

  This invention resides in a hitherto unknown class of chemical compounds, 2H-furo[2,3-c]pyran-2-ones including derivatives and analogues thereof. It includes methods for making compounds within said class and includes, without limitation, at least the intermediates employed in the generation of said compounds. The invention also relates to the use of vinylogous 4H-pyrones, including but not limited to the hitherto unknown 2H-furo[2,3-c]pyran-2-ones. In one aspect the invention resides in a method comprising the step of: exposing biological plant material to at least a compound of the invention to promoting bioactivity within said material. In another aspect the invention resides in methods for promoting growth of plant material in, for example, smoke-responsive plant species by exposing said material to a compound of the invention. More specifically, the invention relates to the use of said compounds for promoting seed germination of a plant, for example, a smoke-responsive plant.

  该发明涉及一类迄今未知的化合物，2H-呋喃[2,3-c]吡喃-2-酮及其衍生物和类似物。它包括制备该类化合物的方法，并包括至少用于生成该类化合物的中间体，但不限于此。该发明还涉及使用乙烯基4H-吡喃，包括但不限于迄今未知的2H-呋喃[2,3-c]吡喃-2-酮。在一方面，该发明涉及一种方法，包括步骤：将生物植物材料暴露于发明中的至少一种化合物中，以促进该材料内的生物活性。在另一方面，该发明涉及通过将该材料暴露于发明中的一种化合物中，来促进例如对烟雾敏感的植物物种中的植物材料的生长的方法。更具体地说，该发明涉及使用该类化合物促进植物的种子萌发，例如对烟雾敏感的植物。
• 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same
  申请人：Tsukamoto Yoshihisa

  公开号：US20050037925A1

  公开（公告）日：2005-02-17

  A compound represented by the formula: [wherein R 1 represents a hydrogen atom, a halogen, atom, alkyl group, etc., R 2 represents a hydrogen atom, a halogen atom, alkyl group, etc., R 3 , R 4 , R 5 , R 6 and R 7 each independently represent a hydrogen atom, a halogen atom, a substitutable alkyl group, a substitutable alkenyl group, alkynyl group, a substituteable cycloalkyl group, etc., or R 3 , R 4 , R 5 , R 6 and R 7 may form a ring which may be substituted, which is formed by the adjacent two of them with carbon atoms to which the respective substituents are bonded, m and n each independently represent 0 or 1.] a salt thereof, an ester derivative thereof and an agricultural chemical containing the same as an effective ingredient, and a herbicidal composition containing the compound and a second herbicidally active compound as effective ingredients.

  一种化合物由以下式子表示：[其中R1代表氢原子，卤素原子，烷基团等，R2代表氢原子，卤素原子，烷基团等，R3，R4，R5，R6和R7各自独立地代表氢原子，卤素原子，可替换的烷基团，可替换的烯基团，炔基团，可替换的环烷基团等，或R3，R4，R5，R6和R7可以形成一个环，该环可以被取代，该环由相邻的两个碳原子形成，这些碳原子与相应的取代基团相连，m和n各自独立地代表0或1。]其盐，酯衍生物及含有该化合物为有效成分的农药，以及含有该化合物和第二种草甘膦活性化合物为有效成分的除草剂组合物。
• 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same
  申请人：Tsukamoto Yoshihisa

  公开号：US20100041555A1

  公开（公告）日：2010-02-18

  A compound represented by the formula: [wherein R 1 represents a hydrogen atom, a halogen atom, alkyl group, etc., R 2 represents a hydrogen atom, a halogen atom, alkyl group, etc., R 3 , R 4 , R 5 , R 6 and R 7 each independently represent a hydrogen atom, a halogen atom, a substitutable alkyl group, a substitutable alkenyl group, alkynyl group, a substitutable cycloalkyl group, etc., or R 3 , R 4 , R 5 , R 6 and R 7 may form a ring which may be substituted, which is formed by the adjacent two of them with carbon atoms to which the respective substituents are bonded, m and n each independently represent 0 or 1.] a salt thereof, an ester derivative thereof and an agricultural chemical containing the same as an effective ingredient, and a herbicidal composition containing the compound and a second herbicidally active compound as effective ingredients.

  一种化合物，其化学式为：[其中R1代表氢原子、卤素原子、烷基等，R2代表氢原子、卤素原子、烷基等，R3、R4、R5、R6和R7各自独立地代表氢原子、卤素原子、可替换的烷基、可替换的烯基、炔基、可替换的环烷基等，或R3、R4、R5、R6和R7可形成一个环，该环可以被取代，由它们中的相邻两个碳原子形成，各自带有相应的取代基，m和n各自独立地代表0或1。]其盐、酯衍生物和含有该化合物作为有效成分的农药，以及含有该化合物和第二种除草活性化合物作为有效成分的除草剂组合物。
• PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
  申请人：Hollick Jonathan James

  公开号：US20110046093A1

  公开（公告）日：2011-02-24

  The present invention relates to a compound of formula (VII)I, or a pharmaceutically acceptable salt or ester thereof, wherein: X is NR 7 ; Y is O or N—(CH 2 ) n R 19 ; n is 1, 2 or 3; m is 1 or 2; R 1 and R 2 are each independently H, alkyl or cycloalkyl; R 4 and R 4′ each independently H alkyl; or R 4 and R 4′ together form a spiro cycloalkyl group; R 19 is H, alkyl, aryl or a cycloalkyl group; R 6 is OR 8 or halogen; and R 7 and R 8 are each independently H or alkyl. Further aspects relate to pharmaceutical compositions comprising said compounds and use therefore in the treatment of proliferative disorders and the like.

  本发明涉及一种化合物，其化学式为(VII)I，或其药学上可接受的盐或酯，其中：X为NR7；Y为O或N-(CH2)nR19；n为1、2或3；m为1或2；R1和R2各自独立地为H、烷基或环烷基；R4和R4′各自独立地为H烷基；或R4和R4′共同形成一个螺环烷基；R19为H、烷基、芳基或环烷基；R6为OR8或卤素；R7和R8各自独立地为H或烷基。此外，该发明还涉及包含上述化合物的制药组合物以及其在治疗增生性疾病等方面的用途。
• Herbicidal emulsion compositions
  申请人：——

  公开号：US20030191024A1

  公开（公告）日：2003-10-09

  A herbicidal emulsion composition comprising an ethenylamide compound as a herbicidally active component and a dichloroacetamide compound as a phytotoxicity reducing agent. This composition has excellent keeping stability because the phytotoxicity reducing agent of the composition does not decompose and crystals do not separate out even when it is kept for a long time. An amino alcohol and a polar nonaqueous solvent as a solvent are added to the ethenylamide compound and the dichloroacetamide compound to prepare a herbicidal emulsion composition.

  一种除草乳剂组合物，包括一种乙烯基酰胺化合物作为除草活性成分和一种二氯乙酰胺化合物作为植物毒性减轻剂。该组合物具有出色的保持稳定性，因为组合物的植物毒性减轻剂即使长时间存放也不会分解和结晶分离。将一种氨基醇和一种极性非水溶剂作为溶剂添加到乙烯基酰胺化合物和二氯乙酰胺化合物中，以制备一种除草乳剂组合物。