(E/Z)-1,2-bis(p-methoxyphenyl)-1-phenylethene | 25346-95-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (E/Z)-1,2-bis(p-methoxyphenyl)-1-phenylethene
• 英文别名: 1,2-bis-(4-methoxy-phenyl)-1-phenyl-ethene；1,2-Bis-(4-methoxy-phenyl)-1-phenyl-aethen；1-Phenyl-1,2-bis-(4-methoxy-phenyl)-aethylen；4,4'-Dimethoxy-α-phenyl-stilben；1,2-Dianisyl-1-phenylethen；1-Methoxy-4-[2-(4-methoxyphenyl)-1-phenylethenyl]benzene
• CAS: 25346-95-6
• 化学式: C₂₂H₂₀O₂
• 分子量: 316.4
• InChiKey: CNEQSUVAQVEEPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2909309090

反应信息

• 作为反应物：
  描述：

  (E/Z)-1,2-bis(p-methoxyphenyl)-1-phenylethene 在 氢氧化钾 作用下， 生成 1,2-bis-(4-hydroxy-phenyl)-1-phenyl-ethene
  参考文献：
  名称：

  Dodds et al., Proceedings of the Royal Society of London. Series B, Biological sciences, 1939, vol. 127, p. 140,153 Anm. 154

  摘要：

  DOI：
• 作为产物：
  描述：

  phenylmagnesium bromide 在 乙酸酐 作用下， 生成 (E/Z)-1,2-bis(p-methoxyphenyl)-1-phenylethene
  参考文献：
  名称：

  Dodds et al., Proceedings of the Royal Society of London. Series B, Biological sciences, 1939, vol. 127, p. 140,153 Anm. 154

  摘要：

  DOI：

文献信息

• Rhodium catalyzed reaction of internal alkynes with organoborons under CO atmosphere: a product tunable reaction
  作者：Levent Artok、Melih Kuş、Özge Aksın-Artok、Fatma Nurcan Dege、Fatma Yelda Özkılınç

  DOI：10.1016/j.tet.2009.09.044

  日期：2009.11

  Alkynes react with organoborons under a CO atmosphere in the presence of a rhodium(I) catalyst to afford mainly 5-aryl-2(5H)-furanones, α,β-unsaturated ketones, and indanones. The product selectivity can be tuned by modifying the reaction conditions.

  炔烃在铑（I）催化剂存在下，在CO气氛下与有机硼反应，主要生成5-芳基-2（5 H）-呋喃酮，α，β-不饱和酮和茚满酮。产物的选择性可以通过改变反应条件来调节。
• Aluminum Chloride Catalyzed Friedel-Crafts Reaction of Anisole with Epoxide Accompanying Isomerization
  作者：Masashi Inoue、Toshio Sugita、Katsuhiko Ichikawa

  DOI：10.1246/bcsj.51.174

  日期：1978.1

  The reaction of anisole with propylene oxide by aluminum chloride has been studied in various kinds of solvents. While the normal Friedel-Crafts reaction yielded 2-(methoxyphenyl)-1-propanols, 1,1-bis(methoxyphenyl)-propanes were also formed in this reaction; these were not obtained by the subsequent reaction of mono(methoxyphenyl) products with another anisole. The yields of 1,1-bis(methoxyphenyl)propanes

  苯甲醚与环氧丙烷在氯化铝作用下的反应已在各种溶剂中进行了研究。虽然正常的 Friedel-Crafts 反应产生 2-(甲氧基苯基)-1-丙醇，但在该反应中也形成 1,1-双(甲氧基苯基)-丙烷；这些不是通过单（甲氧基苯基）产物与另一种苯甲醚的后续反应获得的。1,1-双(甲氧基苯基)丙烷的产率通过增加溶剂的碱性而增加。1,1-双(甲氧基苯基)丙烷的形成机制可以通过环氧化物异构化为醛和随后与苯甲醚缩合来解释。各种环氧化物也在硝基甲烷中生成 1,1-双（甲氧基苯基）烷烃。
• Preparations of Synthetic Estrogens. VIII.^1a New Syntheses of 1,1,2-Tri-p-anisylethylene and Diethylstilbestrol
  作者：Keiiti Sisido、Kôiti Okano、Minoru Sindô、Hitosi Nozaki

  DOI：10.1021/ja01570a077

  日期：1957.7
• Rhodium–copper–TBAF-catalyzed hydroarylation of alkynes with aryl Trimethoxysilanes
  作者：Baoda Lin、Miaochang Liu、Zhishi Ye、Qin Zhang、Jiang Cheng

  DOI：10.1016/j.tetlet.2009.01.130

  日期：2009.4

  A rhodium-copper-TBAF-catalyzed hydroarylation of alkynes with aryl trimethoxysilanes is described. The procedure utilizes a catalytic amount of copper(II) acetate, rhodium, PPh3 and TBAF center dot 3H(2)O under air. Some asymmetric alkynes gave the products with high regioselectivities. (C) 2009 Elsevier Ltd. All rights reserved.
• Palladium-Catalyzed Hydroarylation of Alkynes with Arenediazonium Salts
  作者：Sandro Cacchi、Giancarlo Fabrizi、Antonella Goggiamani、Daniela Persiani

  DOI：10.1021/ol800266e

  日期：2008.4.1

  The palladium-catalyzed hydroarylation of arenediazonium tetrafluoroborates with alkynes in the presence of triphenylsilane affords stereoselectively hydroarylation products in moderate to high yields. The reaction tolerates a variety of substituents including keto, ester, cyano, and nitro groups and can be performed as a one-pot procedure generating the arenediazonium salt in situ. With ethyl phenylpropynoate as the starting alkyne, the hydroarylation affords ethyl (2)-2-arylcinnamates stereo- and regioselectively.