2-methyl-thietane | 17837-41-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 硫杂环丁烷
• 英文名称: 2-methyl-thietane
• 英文别名: 2-Methylthietane
• CAS: 17837-41-1
• 化学式: C₄H₈S
• 分子量: 88.1735
• InChiKey: DUTRXPYVMIFJQZ-UHFFFAOYSA-N

物化性质

• 沸点：
  106°C
• 密度：
  0.957
• 保留指数：
  723

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  5
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2934999090

反应信息

• 作为反应物：
  描述：

  2-methyl-thietane 在 双氧水 作用下， 以 溶剂黄146 为溶剂， 反应 1.0h， 以78%的产率得到2-methylthietane 1,1-dioxide
  参考文献：
  名称：

  Synthesis of 2-alkyl(aryl)thietanes

  摘要：

  Thietane and its 2-substituted derivatives were synthesized. A general preparation procedure for the synthesis of thietanes bearing alkyl and aryl substituents in the (x-position was developed. Using this procedure, 2-substituted thietanes can be obtained from cheap and easily accessible raw materials in three steps. 2-R-Thietanes (where R = H, CH3, C4H9,C5H11,C6H13,C6H5) and the corresponding sulfoxides and sulfones were synthesized and examined. Intermediate and by-products of the synthesis were studied.

  DOI：

  10.1134/s0965544107020089
• 作为产物：
  描述：

  1-溴-3-氯丁烷 在 potassium hydrosulfide 、 氢氧化钾 作用下， 以 乙醇 、 水 为溶剂， 反应 9.0h， 以63%的产率得到2-methyl-thietane
  参考文献：
  名称：

  Synthesis of 2-alkyl(aryl)thietanes

  摘要：

  Thietane and its 2-substituted derivatives were synthesized. A general preparation procedure for the synthesis of thietanes bearing alkyl and aryl substituents in the (x-position was developed. Using this procedure, 2-substituted thietanes can be obtained from cheap and easily accessible raw materials in three steps. 2-R-Thietanes (where R = H, CH3, C4H9,C5H11,C6H13,C6H5) and the corresponding sulfoxides and sulfones were synthesized and examined. Intermediate and by-products of the synthesis were studied.

  DOI：

  10.1134/s0965544107020089

文献信息

• Catalytic synthesis of thiobutyrolactones via CO insertion into the C–S bond of thietanes in the presence of a heterodinuclear organoplatinum–cobalt complex
  作者：Masaki Furuya、Susumu Tsutsuminai、Hiroto Nagasawa、Nobuyuki Komine、Masafumi Hirano、Sanshiro Komiya

  DOI：10.1039/b305799b

  日期：——

  Heterodinuclear organoplatinum-cobalt complex having a 1,2-bis(diphenylphosphino)ethane ligand (dppe)MePt–Co(CO)4 catalyzes CO insertion into the C–S bond of thietanes in THF at 100 °C under 1.0 MPa of CO for 2 h to give γ-thiobutyrolactone in quantitative yield.

  具有1,2-双(二苯基膦基)乙烷配体（dppe）的杂双核有机铂-钴配合物MePt–Co(CO)4能催化CO插入噻丁环的C–S键中，在100℃、1.0 MPa CO条件下，在THF中反应2小时，以定量产率生成γ-硫丁内酯。
• Nagasawa, Kazuo; Yoneta, Akemi, Chemical and pharmaceutical bulletin, 1985, vol. 33, # 11, p. 5048 - 5052
  作者：Nagasawa, Kazuo、Yoneta, Akemi

  DOI：——

  日期：——
• Grischkewitsch-Trochimowski, Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1916, vol. 48, p. 893
  作者：Grischkewitsch-Trochimowski

  DOI：——

  日期：——
• Bennett; Hock, Journal of the Chemical Society, 1927, p. 2497
  作者：Bennett、Hock

  DOI：——

  日期：——
• Thiethan-1-N-arylimide und ihre Umlagerung zu N-Aryl-1,2-thiazolidinen
  作者：Peter K. Claus、Emmerich J�ger

  DOI：10.1007/bf00811249

  日期：1985.10