5,6-bis(4-fluorophenyl)-2-methyl-2,3-dihydropyrazine | 909568-05-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 5,6-bis(4-fluorophenyl)-2-methyl-2,3-dihydropyrazine
• 英文别名: 2,3-bis(4-fluorophenyl)-5-methyl-5,6-dihydropyrazine
• CAS: 909568-05-4
• 化学式: C₁₇H₁₄F₂N₂
• 分子量: 284.308
• InChiKey: YFKVRWSMRGIDHC-UHFFFAOYSA-N

物化性质

• 沸点：
  380.9±52.0 °C(Predicted)
• 密度：
  1.20±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  24.7
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5,6-bis(4-fluorophenyl)-2-methyl-2,3-dihydropyrazine 在 sulfur 作用下， 生成 2,3-bis(p-fluorophenyl)-5-methylpyrazine
  参考文献：
  名称：

  Anti-Platelet Aggregation Activity of Some Pyrazines.

  摘要：

  本报告介绍了 48 种吡嗪类化合物的抗血小板聚集活性。在测试的烷基和芳基吡嗪中，2, 3-二苯基吡嗪的抗血小板聚集活性最强。然后，在苯基上引入了各种取代基，结果发现 2，3-双（对甲氧基苯基）吡嗪衍生物具有相当强的抑制活性。

  DOI：

  10.1248/bpb.20.1076
• 作为产物：
  描述：

  4,4'-二氟安息香 在 ytterbium(III) chloride 、 双氧水 作用下， 以 乙醇 为溶剂， 反应 0.5h， 生成 5,6-bis(4-fluorophenyl)-2-methyl-2,3-dihydropyrazine
  参考文献：
  名称：

  YbCl 3催化一锅合成二氢吡嗪，哌嗪和吡嗪

  摘要：

  开发了一种简单有效的合成方法，该方法在温和条件下通过YbCl 3催化的α-羟基酮与二胺的反应合成二氢吡嗪。通过串联转化二氢吡嗪以良好的产率获得相应的2，3-取代的哌嗪和吡嗪。

  DOI：

  10.1016/j.tetlet.2012.11.005

文献信息

• Organometallic Complex, and Light-Emitting Element, Light-Emitting Device and Electronic- Device Using the Organometallic Complex
  申请人：Inoue Hideko

  公开号：US20090015143A1

  公开（公告）日：2009-01-15

  It is an object of the present invention to provide an organometallic complex which can increase recombination efficiency of electrons and holes. One aspect of the present invention is an organometallic complex having a structure represented by a general formula (1), wherein each of R 1 and R 2 is any of a halogen group, a —CF 3 group, a cyano group, and an alkoxycarbonyl group, each of R 3 and R 4 is any of hydrogen and an alkyl group having 1 to 4 carbon atoms, and M is an element that belongs to Group 9 or 10 of the periodic table.

  本发明的目的是提供一种有机金属配合物，可以增加电子和空穴的复合效率。本发明的一个方面是一种有机金属配合物，其具有由通式（1）表示的结构，其中R1和R2中的每一个都是卤素基团、—CF3基团、氰基团和烷氧羰基基团中的任意一种，R3和R4中的每一个都是氢原子和具有1至4个碳原子的烷基基团中的任意一种，M是属于周期表第9或第10族元素。
• Light emitting device and electronic appliance using the same
  申请人：Ohsawa Nobuharu

  公开号：US20060263636A1

  公开（公告）日：2006-11-23

  The light emitting element includes a first electrode and a second electrode, between which a light emitting layer, a hole transporting layer provide in contact with the light emitting layer, an electron transporting layer provided in contact with the light emitting layer, and a mixed layer provided between the electron transporting layer and the second electrode. The mixed layer includes an electron transporting substance and a substance showing an electron donating property with respect to the electron transporting substance. The light emitting layer includes an organometallic complex represented in General Formula (1) and a host. R 1 and R 2 each represent an electron-withdrawing substituent group. R 3 and R 4 each represent any of hydrogen or an alkyl group having 1 to 4 carbon atoms. L represents any of a monoanionic ligand having a beta-diketone structure, a monoanionic bidentate chelating ligand having a carboxyl group, or a monoanionic bidentate chelating ligand having a phenolic hydroxyl group.

  发光元件包括第一电极和第二电极，在第一电极和第二电极之间提供了一个发光层、一个与发光层接触的空穴传输层、一个与发光层接触的电子传输层和一个位于电子传输层和第二电极之间的混合层。混合层包括一个电子传输物质和一个相对于电子传输物质表现出电子捐赠性质的物质。发光层包括一个在通式（1）中表示的有机金属配合物和一个宿主。R1和R2各代表一个电子吸引取代基。R3和R4各代表氢或具有1至4个碳原子的烷基。L代表具有β-二酮结构的单阴离子配体、具有羧基的单阴离子双齿螯合配体或具有酚羟基的单阴离子双齿螯合配体中的任何一种。
• Light Emitting Device and Electronic Appliance Using the Same
  申请人：Ohsawa Nobuharu

  公开号：US20110298360A1

  公开（公告）日：2011-12-08

  The light emitting element includes a first electrode and a second electrode, between which a light emitting layer, a hole transporting layer provide in contact with the light emitting layer, an electron transporting layer provided in contact with the light emitting layer, and a mixed layer provided between the electron transporting layer and the second electrode. The mixed layer includes an electron transporting substance and a substance showing an electron donating property with respect to the electron transporting substance. The light emitting layer includes an organometallic complex represented in General Formula (1) and a host. R 1 and R 2 each represent an electron-withdrawing substituent group. R 3 and R 4 each represent any of hydrogen or an alkyl group having 1 to 4 carbon atoms. L represents any of a monoanionic ligand having a beta-diketone structure, a monoanionic bidentate chelating ligand having a carboxyl group, or a monoanionic bidentate chelating ligand having a phenolic hydroxyl group.

  发光元件包括第一电极和第二电极，之间有一个发光层，一个与发光层接触的空穴传输层，一个与发光层接触的电子传输层，以及一个位于电子传输层和第二电极之间的混合层。混合层包括一个电子传输物质和一个相对于电子传输物质显示电子给予性质的物质。发光层包括一个在通式（1）中表示的有机金属配合物和一个主体。R1和R2各代表一个电子提取的取代基。R3和R4各代表氢或具有1至4个碳原子的烷基中的任何一个。L表示具有β-二酮结构的单阴离子配体、具有羧基的单阴离子双齿螯合配体或具有酚羟基的单阴离子双齿螯合配体中的任何一个。
• Organometallic complex, and light-emitting element, light-emitting device and electronic-device using the organometallic complex
  申请人：Inoue Hideko

  公开号：US08889266B2

  公开（公告）日：2014-11-18

  It is an object of the present invention to provide an organometallic complex which can increase recombination efficiency of electrons and holes. One aspect of the present invention is an organometallic complex having a structure represented by a general formula (1), wherein each of R1 and R2 is any of a halogen group, a —CF3 group, a cyano group, and an alkoxycarbonyl group, each of R3 and R4 is any of hydrogen and an alkyl group having 1 to 4 carbon atoms, and M is an element that belongs to Group 9 or 10 of the periodic table.

  本发明的目的是提供一种有机金属配合物，该配合物能够提高电子和空穴的复合效率。本发明的一个方面是一种有机金属配合物，其具有由通式（1）表示的结构，其中R1和R2中的每一个都是卤素基团、—CF3基团、氰基团和烷氧羰基基团中的任意一种，R3和R4中的每一个都是氢原子和具有1至4个碳原子的烷基基团中的任意一种，M是属于周期表第9或第10族元素的元素。
• Light-Emitting Device and Electronic Appliance Using the Same
  申请人：Semiconductor Energy Laboratory Co., Ltd.

  公开号：US20160155960A1

  公开（公告）日：2016-06-02

  The light emitting element includes a first electrode and a second electrode, between which a light emitting layer, a hole transporting layer provide in contact with the light emitting layer, an electron transporting layer provided in contact with the light emitting layer, and a mixed layer provided between the electron transporting layer and the second electrode. The mixed layer includes an electron transporting substance and a substance showing an electron donating property with respect to the electron transporting substance. The light emitting layer includes an organometallic complex represented in General Formula (1) and a host. R 1 and R 2 each represent an electron-withdrawing substituent group. R 3 and R 4 each represent any of hydrogen or an alkyl group having 1 to 4 carbon atoms. L represents any of a monoanionic ligand having a beta-diketone structure, a monoanionic bidentate chelating ligand having a carboxyl group, or a monoanionic bidentate chelating ligand having a phenolic hydroxyl group.

  发光元件包括第一电极和第二电极，两者之间有一个发光层、一个与发光层接触的空穴传输层、一个与发光层接触的电子传输层和一个混合层，该混合层包括一个电子传输物质和一个相对于电子传输物质具有电子给予性质的物质。发光层包括一个在一般式（1）中表示的有机金属配合物和一个宿主。R1和R2分别表示电子提取取代基。R3和R4分别表示氢或具有1到4个碳原子的烷基。L表示具有β-二酮结构的单阴离子配体、具有羧基的单阴离子双齿螯合配体或具有酚羟基的单阴离子双齿螯合配体中的任意一种。