Pteridine-6-carboxylic acid | 1955-24-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 蝶啶及其衍生物
• 英文名称: Pteridine-6-carboxylic acid
• CAS: 1955-24-4
• 化学式: C₇H₄N₄O₂
• 分子量: 176.13
• InChiKey: WABAALFDOOSQEE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  88.9
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Assay
  申请人：Frantzen Frank

  公开号：US20050181364A1

  公开（公告）日：2005-08-18

  The present invention relates to a method of assaying for folate in a folate containing sample, wherein at least some of the folate comprises at least one attached glutamate residue. The method comprises subjecting the sample to hydrolysis to release paraminobenzoic acid, p-aminobenzoyl glutamic acid, or a salt thereof; contacting the released paraminobenzoic acid, p-aminobenzoyl glutamic acid, salt or a diazo derivative thereof, with a binding partner thereof; and directly or indirectly detecting the resulting binding partner: paraminobenzoic acid, binding partner: p-aminobenzoyl glutamic acid, or salt or derivative combination. The invention further relates to a kit usable in the method of the invention.

  本发明涉及一种检测含叶酸样品中叶酸含量的方法，其中至少部分叶酸包含至少一个附着的谷氨酸残基。该方法包括将样品水解以释放对氨基苯甲酸、对氨基苯甲酰基谷氨酸或其盐；将释放的对氨基苯甲酸、对氨基苯甲酰基谷氨酸、其盐或重氮衍生物与其结合剂接触；以及直接或间接检测所产生的结合剂：对氨基苯甲酸、结合剂：对氨基苯甲酰基谷氨酸、或其盐或衍生物组合。本发明还涉及一种可用于本发明方法的试剂盒。
• FOLATE ASSAY
  申请人：AXIS-SHIELD ASA

  公开号：EP1472545A2

  公开（公告）日：2004-11-03
• [EN] ASSAY<br/>[FR] DOSAGE DU FOLATE
  申请人：AXIS SHIELD ASA

  公开号：WO2003067263A2

  公开（公告）日：2003-08-14

  The present invention relates to a method of assaying for folate in a folate containing sample, wherein at least some of the folate comprises at least one attached glutamate residue. The method comprises subjecting the sample to hydrolysis to release paraaminobenzoic acid, p-aminobenzoyl glutamic acid, or a salt thereof; contacting the released paraaminobenzoic acid, p-aminobenzoyl glutamic acid, salt or a diazo derivative thereof, with a binding partner thereof; and directly or indirectly detecting the resulting binding partner: paraaminobenzoic acid, binding partner: p-aminobenzoyl glutamic acid, or salt or derivative combination. The invention further relates to a kit usable in the method of the invention.