(±)-5-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methylchroman-2-one | 1945993-01-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 新黄酮类化合物
• 英文名称: (±)-5-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methylchroman-2-one
• 英文别名: IR9JJ55Hju；5-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methyl-3,4-dihydrochromen-2-one
• CAS: 1945993-01-0
• 化学式: C₁₇H₁₆O₅
• 分子量: 300.311
• InChiKey: MWXZMODKQTZDPU-UHFFFAOYSA-N

物化性质

• 沸点：
  429.0±45.0 °C(Predicted)
• 密度：
  1.333±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  (±)-5-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methylchroman-2-one 在 CHIRALPAK AD-H 作用下， 以 异丙醇 为溶剂， 以1.3 g的产率得到(R)-5-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methylchroman-2-one
  参考文献：
  名称：

  COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE

  摘要：

  本公开说明提供了包含味级甜味调节剂或味级苦味阻断剂或二者组合的食品组成物，以及包含这种可食用组成物的食品产品和制备这种食品产品的方法。本公开说明还提供了减少食品产品中糖含量的方法、减少饮食热量摄入的方法，以及增强食品产品的甜味或阻断苦味的方法。

  公开号：

  US20210282443A1
• 作为产物：
  描述：

  orcinol glucoside 在 L-苹果酸 、 L-酒石酸 、 β-D-glucoside glycohydrolase from almonds 作用下， 以 aq. acetate buffer 为溶剂， 反应 1.0h， 生成 (±)-5-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methylchroman-2-one
  参考文献：
  名称：

  COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE

  摘要：

  本公开说明提供了包含味级甜味调节剂或味级苦味阻断剂或二者组合的食品组成物，以及包含这种可食用组成物的食品产品和制备这种食品产品的方法。本公开说明还提供了减少食品产品中糖含量的方法、减少饮食热量摄入的方法，以及增强食品产品的甜味或阻断苦味的方法。

  公开号：

  US20210282443A1

文献信息

• Compounds, compositions, and methods for modulating sweet taste
  申请人：Chromocell Corporation

  公开号：US10407400B2

  公开（公告）日：2019-09-10

  The present disclosure provides edible compositions comprising a flavor-grade sweet taste modulator or a combination of flavor-grade sweet taste modulators or a flavor-grade bitter taste blocker or a combination of flavor-grade bitter taste blockers of the present disclosure, food products comprising such edible compositions and methods of preparing such food products. The present disclosure also provides methods of reducing the amount of sugar in a food product, methods of reducing the caloric intake in a diet, and methods of enhancing sweet taste or blocking a bitter taste in a food product.

  本公开提供了包含本公开的风味级甜味调节剂或风味级甜味调节剂的组合或风味级苦味阻断剂或风味级苦味阻断剂的组合的可食用组合物、包含这种可食用组合物的食品以及制备这种食品的方法。本公开还提供了减少食品中糖分含量的方法、减少饮食中热量摄入的方法，以及增强食品中甜味或阻断苦味的方法。
• COMPOSITIONS AND METHODS FOR MODULATING SWEET TASTE
  申请人：Chromocell Corporation

  公开号：EP3245197B1

  公开（公告）日：2019-07-03
• [EN] COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE<br/>[FR] COMPOSÉS, COMPOSITIONS ET PROCÉDÉS PERMETTANT DE MODULER LE GOÛT SUCRÉ
  申请人：CHROMOCELL CORP

  公开号：WO2016115263A1

  公开（公告）日：2016-07-21

  The present disclosure provides edible compositions comprising a sweet taste modulator or bitter taste blocker of the present disclosure, food products comprising such edible compositions and methods of preparing such food products. The present disclosure also provides methods of reducing the amount of sugar in a food product, methods of reducing the caloric intake in a diet, and methods of enhancing sweet taste or blocking a bitter taste in a food product.
• [EN] COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE<br/>[FR] COMPOSÉS, COMPOSITIONS, ET PROCÉDÉS DE MODULATION DU GOÛT SUCRÉ
  申请人：CHROMOCELL CORP

  公开号：WO2016115278A1

  公开（公告）日：2016-07-21

  The present disclosure provides edible compositions comprising a flavor- grade sweet taste modulator or a combination of flavor-grade sweet taste modulators or a flavor-grade bitter taste blocker or a combination of flavor-grade bitter taste blockers of the present disclosure, food products comprising such edible compositions and methods of preparing such food products. The present disclosure also provides methods of reducing the amount of sugar in a food product, methods of reducing the caloric intake in a diet, and methods of enhancing sweet taste or blocking a bitter taste in a food product.
• [EN] METHODS, COMPOUNDS, AND COMPOSITIONS, FOR MODULATING SWEET TASTE<br/>[FR] PROCÉDÉS, COMPOSÉS, ET COMPOSITIONS POUR MODULER UN GOÛT SUCRÉ
  申请人：CHROMOCELL CORP

  公开号：WO2017189778A1

  公开（公告）日：2017-11-02

  The present invention provides methods of improving the taste of sweeteners and sweet taste modulator, comprising esterifying one or more hydroxyl groups of such sweetener and sweet taste modulator, edible compositions comprising such improved sweeteners and improved sweet taste modulator, food and beverage products comprising such edible composition, and methods of preparing such food products.