2-乙基肉桂醛 | 103907-09-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂醛
• 中文名称: 2-乙基肉桂醛
• 英文名称: 2-ethylcinnamaldehyde
• 英文别名: 2-ethyl-trans-cinnamaldehyde；2-Aethyl-trans-zimtaldehyd；a-Ethylcinnamaldehyde；(E)-3-(2-ethylphenyl)prop-2-enal
• CAS: 103907-09-1
• 化学式: C₁₁H₁₂O
• 分子量: 160.216
• InChiKey: WTLFSSCVUTYPAD-VMPITWQZSA-N

物化性质

• 沸点：
  88 °C(Press: 0.2 Torr)
• 密度：
  0.997±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-乙基肉桂醛 在 乙醇 、 silver nitrate 作用下， 生成 (2E)-3-(2-乙基苯基)丙烯酸
  参考文献：
  名称：

  Cyclic Polyolefins. XLI. Reaction of Acetyl Bromide and Propionyl Chloride with Cycloöctatetraene

  摘要：

  DOI：

  10.1021/ja01558a063
• 作为产物：
  描述：

  2-乙基苯甲酰氯 在 喹啉 、 Pd-BaSO₄ 、 sulfur 作用下， 生成 2-乙基肉桂醛
  参考文献：
  名称：

  Cyclic Polyolefins. XLI. Reaction of Acetyl Bromide and Propionyl Chloride with Cycloöctatetraene

  摘要：

  DOI：

  10.1021/ja01558a063

文献信息

• Process for producing indenol esters or ethers
  申请人：Womack Bernard Gary

  公开号：US20070032402A1

  公开（公告）日：2007-02-08

  The present invention relates to a process for making indenol esters or ether from an α-substituted cinnamic aldehyde derivative such as an acetal or an acylal. Said reaction is promoted by the use of strong mineral acids, sulphonic acids, acidic zeolites or Lewis acids.

  本发明涉及一种从α-取代肉桂醛衍生物，如缩醛或酰缩醛，制备茚醇酯或茚醚的过程。该反应通过使用强矿酸、磺酸、酸性沸石或Lewis酸来促进。
• Corrosion inhibitors containing N,N,1-trisubstituted prop-2-ynyl amines
  申请人：GAF CORPORATION

  公开号：EP0080794A1

  公开（公告）日：1983-06-08

  A novel acetylenic amine and an aqueous composition containing said amine for inhibiting the corrosion of metals is described. The composition comprises a non-oxidizing acid, and, as a corrosion inhibitor, an effective amount of tertiary amine containing acetylenic unsaturation having the formula: wherein R1 and R2 are independently C1-C8 alkyl or phenyl and R3 is selected from the group of branched chain C7-C10 alkyl, cinnamyl optionally mono- or di-substituted with halo, C1-C8 alkyl and/or C1-C8 alkoxy; mono- or di-similarly substituted phenyl or, when R1 and R2 are other than C1-C2 alkyl, then R3 can be unsubstituted phenyl.

  本文描述了一种新型乙炔胺和含有该胺的水性组合物，用于抑制金属腐蚀。该组合物包含一种非氧化性酸，以及作为缓蚀剂的有效量的含乙炔不饱和叔胺，其式如下 其中 R1 和 R2 独立地为 C1-C8 烷基或苯基，R3 选自支链 C7-C10 烷基、任选与卤素、C1-C8 烷基和/或 C1-C8 烷氧基单取代或二取代的肉桂基、单取代或二取代的苯基，或者当 R1 和 R2 不是 C1-C2 烷基时，R3 可以是未取代的苯基。
• Design and synthesis of piperidine farnesyltransferase inhibitors with reduced glucuronidation potential
  作者：Rieko Tanaka、Almudena Rubio、Nancy K. Harn、Douglas Gernert、Timothy A. Grese、Jun Eishima、Mitsunobu Hara、Nobuyuki Yoda、Rui Ohashi、Takashi Kuwabara

  DOI：10.1016/j.bmc.2006.11.007

  日期：2007.2.1

  The design and synthesis of a novel piperidine series of farnesyltransferase (FTase) inhibitors with reduced potential for metabolic glucuronidation are described. The various substitution and exchange of the phenyl group at the C-2 position of the previously described 2-(4-hydroxy)phenyl-3-nitropiperidine 1a (FTase IC50 = 5.4 nM) resulted in metabolically stable compounds with potent FTase inhibition (14a IC50 = 4.3 nM, 20a IC50 = 3.0 nM, and 50a IC50 = 16 nM). Molecular modeling studies of these compounds complexed with FTasc and farnesyl pyrophosphate are also described. (c) 2006 Elsevier Ltd. All rights reserved.
• Indanones and Indenols from 2-Alkylcinnamaldehydes via the Intramolecular Friedel−Crafts Reaction of Geminal Diacetates
  作者：Gary B. Womack、John G. Angeles、Vincent E. Fanelli、Brinda Indradas、Roger L. Snowden、Philippe Sonnay

  DOI：10.1021/jo900910b

  日期：2009.8.7

  When treated with Ac(2)O at rt in the presence of 4-6 mol% FeCl(3), 2-alkylcinnamaldehydes are converted to 2-alkyl-1H-inden-1-yl acetates through the intermediacy of gemdiacetates. Methanolysis of the indenyl acetates yields the corresponding indenols, Saponification yields 2-alkylindanones, providing, in effect, an intramolecular acylation employing catalytic levels of acid.
• METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION
  申请人：HALLIBURTON ENERGY SERVICES, INC.

  公开号：EP1689911A1

  公开（公告）日：2006-08-16