acetic acid-(4-methyl-[1]naphthylmethyl ester) | 49675-07-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: acetic acid-(4-methyl-[1]naphthylmethyl ester)
• 英文别名: Essigsaeure-(4-methyl-[1]naphthylmethylester)；1-Acetoxymethyl-4-methyl-naphthalin；1-Methyl-4-acetoxymethyl-naphthalin；(4-Methylnaphthalen-1-yl)methyl acetate
• CAS: 49675-07-2
• 化学式: C₁₄H₁₄O₂
• 分子量: 214.264
• InChiKey: XSRITZAFLFJHEP-UHFFFAOYSA-N

物化性质

• 熔点：
  42.5 °C
• 沸点：
  145-155 °C(Press: 14 Torr)
• 密度：
  1.112±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  acetic acid-(4-methyl-[1]naphthylmethyl ester) 在 氢氧化钾 作用下， 生成 (1-甲基萘-4-基)甲醇
  参考文献：
  名称：

  Lock; Schneider, Chemische Berichte, 1951, vol. 84, p. 636,640

  摘要：

  DOI：
• 作为产物：
  描述：

  1,4-二甲基萘 在 ammonium cerium(IV) nitrate 作用下， 以 水 、 溶剂黄146 为溶剂， 反应 2.0h， 以6%的产率得到acetic acid-(4-methyl-[1]naphthylmethyl ester)
  参考文献：
  名称：

  硝酸铈（Ⅳ）铵氧化甲基萘制备萘醛

  摘要：

  当在50％HOAc中于85°C下用硝酸铈（IV）铵铵（CAN）氧化时，在1位上具有Me基的萘产生的醛收率非常好。在相同条件下，在周边位置没有Me基的甲基萘以适当的收率得到醛，但是也产生了大量的1,4-萘醌。

  DOI：

  10.1016/s0040-4020(01)91375-4

文献信息

• NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS
  申请人：Lahm George Philip

  公开号：US20100254959A1

  公开（公告）日：2010-10-07

  Disclosed are compounds of Formula 1, wherein R 1 is halogen, C 1 -C 2 haloalkyl or C 1 -C 2 haloalkoxy; R 2 is H, halogen or cyano; R 3 is H, halogen or CF 3 ; R 4 is H, C 2 -C 7 alkylcarbonyl or C 2 -C 7 alkoxycarbonyl; and R 5 is C 1 -C 6 alkyl or C 1 -C 6 haloalkyl, each substituted with one substituent independently selected from hydroxy, C 1 -C 6 alkoxy, C 1 -C 6 alkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 2 -C 7 alkylaminocarbonyl, C 3 -C 9 dialkylaminocarbonyl, C 2 -C 7 haloalkylaminocarbonyl and C 3 -C 9 halodialkylaminocarbonyl. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

  本文披露了Formula 1的化合物，其中R1是卤素，C1-C2卤代烷基或C1-C2卤代氧烷基；R2是H、卤素或氰基；R3是H、卤素或三氟甲基；R4是H、C2-C7烷基羰基或C2-C7烷氧羰基；R5是C1-C6烷基或C1-C6卤代烷基，每个都被一个取自羟基、C1-C6烷氧基、C1-C6烷基硫醚、C1-C6烷基亚砜基、C1-C6烷基砜基、C2-C7烷基氨基羰基、C3-C9二烷基氨基羰基、C2-C7卤代烷基氨基羰基和C3-C9卤代二烷基氨基羰基的取代基独立取代。还披露了含有Formula 1化合物的组合物以及用于控制无脊椎动物害虫的方法，包括将无脊椎动物害虫或其环境与本发明的化合物或组合物的生物有效量接触。
• Isoxazolines for Controlling Invertebrate Pests
  申请人：Lahm George Philip

  公开号：US20100234219A1

  公开（公告）日：2010-09-16

  Disclosed are compounds of Formula (1), including all geometric and stereoisomers, N-oxides, and salts thereof, Formula (1): wherein A 1 , A 2 , A 3 , A 4 , A 5 and A 6 are independently, selected from the group consisting of CR 3 and N; provided that at most 3 of A 1 , A 2 , A 3 ; A 4 , A 5 and A 6 is N; B 1 , B 2 and B 3 are independently selected from the group consisting of CR 2 . and N; each R 3 is independently H, halogen, C 1 -C 6 alkyl, C1-C6 haloalkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C1-C6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfo?yl, C 1 -C 6 alkylamino, C 2 -G 6 dialkylamino, —CN or —NO 2 ; and R 1 , R 2 , R 4 , R 5 , W and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (1) and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

  本发明公开了式（1）的化合物，包括所有的几何和立体异构体、N-氧化物和其盐，式（1）：其中，A1、A2、A3、A4、A5和A6独立地选自CR3和N的群组，但最多只有3个为N；B1、B2和B3独立地选自CR2和N的群组；每个R3独立地选自H、卤素、C1-C6烷基、C1-C6卤代烷基、C3-C6环烷基、C3-C6卤代环烷基、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基硫基、C1-C6卤代烷基硫基、C1-C6烷基亚磺酰基、C1-C6卤代烷基亚磺酰基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、C1-C6烷基氨基、C2-G6二烷基氨基、—CN或—NO2；以及R1、R2、R4、R5、W和n在本文中的定义。本发明还公开了含有式（1）的化合物的组合物以及用一种本发明的化合物或组合物的生物有效量与无脊椎动物害虫或其环境接触来控制无脊椎动物害虫的方法。
• ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS
  申请人：LAHM George Philip

  公开号：US20130029845A1

  公开（公告）日：2013-01-31

  Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A 1 , A 2 , A 3 , A 4 , A 5 and A 6 are independently selected from the group consisting of CR 3 and N; provided that at most 3 of A 1 , A 2 , A 3 , A 4 , A 5 and A 6 is N; B 1 , B 2 and B 3 are independently selected from the group consisting of CR 2 and N; each R 3 is independently H, halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, C 1 -C 6 alkylamino, C 2 -C 6 dialkylamino, —CN or —NO 2 ; and R 1 , R 2 , R 4 , R 5 , W and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

  本发明公开了一种式子1的化合物，包括所有的几何和立体异构体、N-氧化物和其盐，其中A1、A2、A3、A4、A5和A6独立地选自CR3和N的群组，前提是A1、A2、A3、A4、A5和A6中最多只有3个是N；B1、B2和B3独立地选自CR2和N的群组；每个R3独立地为H、卤素、C1-C6烷基、C1-C6卤代烷基、C3-C6环烷基、C3-C6卤代环烷基、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基硫基、C1-C6卤代烷基硫基、C1-C6烷基亚砜基、C1-C6卤代烷基亚砜基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、C1-C6烷基氨基、C2-C6双烷基氨基、—CN或—NO2；以及R1、R2、R4、R5、W和n如所述。本发明还公开了包含式子1化合物的组合物以及用化合物或本发明的组合物的生物有效量接触无脊椎动物害虫或其环境来控制无脊椎动物害虫的方法。
• Isoxazolines For Controlling Invertebrate Pests
  申请人：Lahm George Philip

  公开号：US20110263641A1

  公开（公告）日：2011-10-27

  Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A 1 , A 2 , A 3 , A 4 , A 5 and A 6 are independently selected from the group consisting of CR 3 and N; provided that at most 3 of A 1 , A 2 , A 3 , A 4 , A 5 and A 6 is N; B 1 , B 2 and B 3 are independently selected from the group consisting of CR 2 and N; each R 3 is independently H, halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 halo alkylthio, C 1 -C 6 alkyl sulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, C 1 -C 6 alkylamino, C 2 -C 6 dialkylamino, —CN or —NO 2 ; and R 1 , R 2 , R 4 , R 5 , W and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

  本发明涉及公式1的化合物，包括所有的几何和立体异构体、N-氧化物和其盐，其中A1、A2、A3、A4、A5和A6独立地选自CR3和N的群组，但最多只有3个A1、A2、A3、A4、A5和A6是N；B1、B2和B3独立地选自CR2和N的群组；每个R3独立地选自H、卤素、C1-C6烷基、C1-C6卤代烷基、C3-C6环烷基、C3-C6卤代环烷基、C1-C6烷氧基、C1-C6卤代烷氧基、C1-C6烷基硫基、C1-C6卤代烷基硫基、C1-C6烷基亚砜基、C1-C6卤代烷基亚砜基、C1-C6烷基磺酰基、C1-C6卤代烷基磺酰基、C1-C6烷基氨基、C2-C6二烷基氨基、—CN或—NO2；R1、R2、R4、R5、W和n如本文所定义。本发明还涉及含有公式1化合物的组合物和控制无脊椎动物害虫的方法，包括将该化合物或本发明的组合物的生物有效量与无脊椎动物害虫或其环境接触。
• Naphthalene Isoxazoline Invertebrate Pest Control Agents
  申请人：E. I. Du Pont de Nemours and Company

  公开号：US20130217736A1

  公开（公告）日：2013-08-22

  Disclosed are compounds of Formula 1, wherein R 1 is halogen, C 1 -C 2 haloalkyl or C 1 -C 2 haloalkoxy; R 2 is H, halogen or cyano; R 3 is H, halogen or CF 3 ; R 4 is H, C 2 -C 7 alkylcarbonyl or C 2 -C 7 alkoxycarbonyl; and R 5 is C 1 -C 6 alkyl or C 1 -C 6 haloalkyl, each substituted with one substituent independently selected from hydroxy, C 1 -C 6 alkoxy, C 1 -C 6 alkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 2 -C 7 alkylaminocarbonyl, C 3 -C 9 dialkylaminocarbonyl, C 2 -C 7 haloalkylaminocarbonyl and C 3 -C 9 halodialkylaminocarbonyl. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

  本发明涉及一种化合物，其化学式为1，其中R1为卤素，C1-C2卤代烷基或C1-C2卤代氧烷基；R2为H，卤素或氰基；R3为H，卤素或CF3；R4为H，C2-C7烷基羰基或C2-C7烷氧羰基；R5为C1-C6烷基或C1-C6卤代烷基，每个烷基上都独立地取代一个取代基，所述取代基选择自羟基、C1-C6烷氧基、C1-C6烷基硫醚基、C1-C6烷基亚砜基、C1-C6烷基磺酰基、C2-C7烷基氨基羰基、C3-C9二烷基氨基羰基、C2-C7卤代烷基氨基羰基和C3-C9卤代二烷基氨基羰基。本发明还涉及含有化合物1的组合物以及用化合物或本发明的组合物的生物有效量与无脊椎动物害虫或其环境接触以控制无脊椎动物害虫的方法。