2-十二烷-2-基苯酚 | 21566-82-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 2-十二烷-2-基苯酚
• 英文名称: 2-(1-Methylundecyl)phenol
• 英文别名: 2-(2-dodecyl)phenol；2-(Dodecan-2-YL)phenol；2-dodecan-2-ylphenol
• CAS: 21566-82-5
• 化学式: C₁₈H₃₀O
• 分子量: 262.436
• InChiKey: PCONHAXLMNWOQO-UHFFFAOYSA-N

物化性质

• 沸点：
  156-157 °C(Press: 0.4 Torr)
• 密度：
  0.9213 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-十二烷-2-基苯酚 以72%的产率得到
  参考文献：
  名称：

  TANCHUK, YU. V.;KOTENKO, S. I., YKP. XIM. ZH., 54,(1988) N 1, 81-85

  摘要：

  DOI：
• 作为产物：
  描述：

  1-十二烯十二碳烯α-十二碳烯α-十二碳烯 、 苯酚 在 三氯化铝 作用下， 以 氯仿 为溶剂， 反应 10.0h， 以52%的产率得到2-十二烷-2-基苯酚
  参考文献：
  名称：

  酸度在苯酚与烯烃烷基化的区域化学控制中的作用

  摘要：

  在室温下，苯酚与直链烯烃的1:1混合物在CHCl3中加入酸性促进剂处理后，会进行邻位区域选择性单烷基化反应，生成次烷基苯酚，产率可达48-60%。类似反应中，支链烯烃则仅产生相应的对叔烷基苯酚，产率为80-85%。向反应体系中添加越来越多的苯酚钾，会降低质子酸度并促进邻位区域选择性的叔烷基化反应。这些结果初步解释为“氢键模板”和“电荷控制”机制之间的竞争。

  DOI：

  10.1039/a604598g

文献信息

• Alkylation of Phenol by 1-Dodecene and 1-Decanol. A Literature Correction
  作者：Curt B. Campbell、Anatoli Onopchenko、Donald S. Santilli

  DOI：10.1246/bcsj.63.3665

  日期：1990.12

  literature report that 1-dodecene reacts with phenol in the presence of sulfated zirconium oxide (superacid), or 1-dodecanol with phenol in the precsence of H-Mordenite (zeolite), to afford mostly para-substituted alkylphenols has been shown to be incorrect. The product with zirconium is a mixture of ortho/para isomers (≈50–65/50–35), and not the exclusive para isomer as reported. The major product in the

  最近的一篇文献报道称，在硫酸化氧化锆（超强酸）存在下，1-十二烯与苯酚反应，或在 H-丝光沸石（沸石）存在下，1-十二烷醇与苯酚反应，主要提供对位取代的烷基苯酚。不正确。含锆的产品是邻位/对位异构体 (≈50–65/50–35) 的混合物，而不是报道的唯一对位异构体。在沸石催化的情况下，主要产物是邻烷基苯酚，具有高度的末端连接，而不是主要要求保护的对位异构体。在苯酚烷基化过程中用 H-丝光沸石获得的选择性不同于烷基苯和苯甲醚的烷基化，最好根据表面催化现象进行解释。
• N-Substituted Carbamic Acid Ester Production Method, Isocyanate Production Method Using Such N-Substituted Carbamic Acid Ester, And Composition For Transfer And Storage Of N-Substituted Carbamic Acid Ester Comprising N-Substituted Carbamic Acid Ester and Aromatic Hydroxy Compound
  申请人：Shinohata Masaaki

  公开号：US20110133121A1

  公开（公告）日：2011-06-09

  The present invention is a method for producing an N-substituted carbamic acid ester derived from an organic amine from an organic amine, a carbonic acid derivative and a hydroxy composition containing one or more types of hydroxy compounds, wherein the organic amine, the carbonic acid derivative and the hydroxy composition are reacted using a urethane production reaction vessel provided with a condenser, a gas containing the hydroxy composition, the compound having the carbonyl group derived from the carbonic acid derivative, and an ammonia formed as a by-product in the reaction, is introduced into the condenser provided in the urethane production reaction vessel, and the hydroxy composition and the compound having the carbonyl group derived from the carbonic acid derivative are condensed, and wherein a stoichiometric ratio of a hydroxy compound contained in the condensed hydroxy composition to the condensed compound having the carbonyl group derived from the carbonic acid derivative is 1 or more, and a ratio of number of carbonyl groups (—C(═O)—) contained in the compound having the carbonyl group derived from the carbonic acid derivative and number of ammonia molecules contained in the ammonia recovered as a gas from the condenser is 1 or less.

  本发明涉及一种从有机胺、碳酸衍生物和含有一种或多种羟基化合物中制得的N-取代氨基甲酸酯的制备方法，其中使用一种含有冷凝器的脲类生产反应容器反应有机胺、碳酸衍生物和羟基化合物，将含有羟基化合物的气体、来自碳酸衍生物衍生的含有羰基基团的化合物、以及在反应中形成的氨气体引入到脲类生产反应容器中的冷凝器中，使羟基化合物和含有羰基基团的化合物冷凝，其中在冷凝的羟基化合物中所含有的羟基化合物与冷凝的含有羰基基团的化合物中所含有的羰基基团的化合物的比例为1或更多，而且在从冷凝器中回收的氨气体中所含有的羰基基团（—C(═O)—）数与氨分子数的比例为1或更少。
• N-Substituted Carbamic Acid Ester Production Method, Isocyanate Production Method Using Such N-Substituted Carbamic Acid Ester, and Composition for Transfer and Storage of N-Substituted Carbamic Acid Ester Comprising N-Substituted Carbamic Acid Ester and Aromatic Hydroxy Compound
  申请人：Asahi Kasei Chemicals Corporation

  公开号：US20140194650A1

  公开（公告）日：2014-07-10

  The present invention is a method for producing an N-substituted carbamic acid ester derived from an organic amine from an organic amine, a carbonic acid derivative and a hydroxy composition containing one or more types of hydroxy compounds, wherein the organic amine, the carbonic acid derivative and the hydroxy composition are reacted using a urethane production reaction vessel provided with a condenser, a gas containing the hydroxy composition, the compound having the carbonyl group derived from the carbonic acid derivative, and an ammonia formed as a by-product in the reaction, is introduced into the condenser provided in the urethane production reaction vessel, and the hydroxy composition and the compound having the carbonyl group derived from the carbonic acid derivative are condensed, and wherein a stoichiometric ratio of a hydroxy compound contained in the condensed hydroxy composition to the condensed compound having the carbonyl group derived from the carbonic acid derivative is 1 or more, and a ratio of number of carbonyl groups (—C(═O)—) contained in the compound having the carbonyl group derived from the carbonic acid derivative and number of ammonia molecules contained in the ammonia recovered as a gas from the condenser is 1 or less.

  本发明是一种从有机胺、碳酸酯衍生物和含有一种或多种羟基化合物中制备N-取代的氨基甲酸酯的方法，其中利用一种尿素生产反应容器反应有机胺、碳酸酯衍生物和羟基化合物，该反应容器配有冷凝器，将含有羟基化合物的气体、由碳酸酯衍生物产生的含有羰基基团的化合物以及在反应中生成的氨引入到尿素生产反应容器中的冷凝器中，将羟基化合物和含有羰基基团的碳酸酯衍生物冷凝，其中在冷凝的羟基化合物中所含的羟基化合物的化学计量比与所冷凝的含有羰基基团的化合物的化学计量比为1或更多，而且所含有羰基基团的化合物中所含的羰基基团（-C(═O)-）的数量与从冷凝器中回收的氨分子数量的比率为1或更小。
• Stabilisiertes Weich-PVC
  申请人：CIBA-GEIGY AG

  公开号：EP0677551A2

  公开（公告）日：1995-10-18

  Durch Verwendung eines Perchlorates und einer endständigen Epoxidverbindung wird eine hohe Stabilisierung von Weich-PVC erreicht.

  使用高氯酸盐和终端环氧化合物可实现软聚氯乙烯的高度稳定。
• Stabilizing mixtures for organic polymers
  申请人：Great Lakes Chemical (Europe) GmbH

  公开号：EP1110999A2

  公开（公告）日：2001-06-27

  Stabilizing mixtures for organic polymers comprising: a) at least one compound belonging to the group of pyrazolones; b) at least one compound belonging to the group of organic phosphites or phosphonites; c) at least one compound belonging to the group of sterically hindered phenols; and optionally d) at least one compound belonging to the group of sterically hindered amines. The above mixtures are useful in the stabilization to degradation caused by oxygen, heat and/or light, of organic polymers.

  用于有机聚合物的稳定混合物，包括 a) 至少一种属于吡唑酮类的化合物； b) 至少一种属于有机亚磷酸酯或亚磷酸酯类的化合物； c) 至少一种属于立体受阻酚类的化合物；以及 d) 至少一种属于立体受阻胺类的化合物。 上述混合物可用于稳定有机聚合物，使其不受氧、热和/或光的影响而降解。