环己基-(环己基-氧代氨基)-氧代铵 | 26049-06-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 环己基-(环己基-氧代氨基)-氧代铵
• 英文名称: N,N'-dicyclohexyldiazene N,N'-dioxide
• 英文别名: Bis(nitrosocyclohexan)；Azocyclohexane N,N'-dioxide；(E)-cyclohexyl-[cyclohexyl(oxido)azaniumylidene]-oxidoazanium
• CAS: 26049-06-9
• 化学式: C₁₂H₂₂N₂O₂
• 分子量: 226.319
• InChiKey: IQCWPIHWVLBCTQ-BUHFOSPRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  57.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  环己基-(环己基-氧代氨基)-氧代铵 以 neat (no solvent) 为溶剂， 反应 0.5h， 生成 环己酮肟
  参考文献：
  名称：

  烷烃的光化学流氧化

  摘要：

  使用亚硝酸叔丁酯的几种烷烃的亚硝化已经在流动中进行，与批处理相比，反应时间显着减少。由于需要大量过量的烷烃组分，设计了连续循环工艺以制备更大量的材料。

  DOI：

  10.1055/s-0040-1707281
• 作为产物：
  描述：

  硝基环己烷 在 sodium hydrogen telluride 作用下， 以80%的产率得到环己基-(环己基-氧代氨基)-氧代铵
  参考文献：
  名称：

  通过碲化氢钠减少芳香族和脂肪族硝基化合物

  摘要：

  各种硝基化合物被碲化氢钠以良好的收率有效还原。因此，实现了不受阻碍的硝基苯还原转化为偶氮苯，空间位阻硝基苯还原转化为苯胺，硝基烷烃还原转化为亚硝基烷烃的二聚体，以及连位二硝基烷烃还原转化为烯烃。

  DOI：

  10.1246/cl.1983.1373

文献信息

• Methyltrioxorhenium-Catalyzed Oxidation of Secondary and Primary Amines with Hydrogen Peroxide
  作者：Shigekazu Yamazaki

  DOI：10.1246/bcsj.70.877

  日期：1997.4

  The methyltrioxorhenium-catalyzed oxidation of secondary amines and primary amines with hydrogen peroxide has been carried out. The oxidation of secondary amines afforded nitrones in good-to-excellent yield. Benzylamines were selectively oxidized to oximes, while general primary alkylamines possessing the α-C–H bond gave mixtures of oximes, nitroso dimers, and azoxy compounds.

  用过氧化氢对仲胺和伯胺进行了甲基三氧铼催化氧化。仲胺的氧化以良好至极好的收率提供硝酮。苄胺被选择性氧化为肟，而具有 α-C-H 键的一般伯烷基胺生成肟、亚硝基二聚体和氧化偶氮化合物的混合物。
• METHOD FOR PRODUCING C4-C15 LACTAMS
  申请人：BASF SE

  公开号：US20190040005A1

  公开（公告）日：2019-02-07

  The present invention relates to a process for preparing C 4 -C 15 lactams, in which a C 1 -C 10 -alkyl nitrite is reacted with a C 4 -C 15 -cycloalkane and is illuminated with a light-emitting diode during the reaction. This forms a C 4 -C 15 -cyclohexanone oxime which is then converted further to a C 4 -C 15 lactam; the C 1 -C 10 alcohol formed is recycled into the preparation of the C 1 -C 10 -alkyl nitrite.

  本发明涉及一种制备C4-C15内酰胺的方法，其中将C1-C10烷基亚硝酸酯与C4-C15环烷烃反应，并在反应过程中照射LED光。这样形成了C4-C15环己酮肟，然后进一步转化为C4-C15内酰胺；生成的C1-C10醇被回收再用于制备C1-C10烷基亚硝酸酯。
• The Reaction of Nitrosoalkane Dimers with Acid Halides
  作者：Max A. Ribi、Emil H. White

  DOI：10.1002/hlca.19750580116

  日期：——

  Nitrosoalkane dimers react with acid halides to yield α-halogeno-azoxy compounds with the substituent α to the oxygen-bearing nitrogen. In the presence of silver carbonate, the corresponding α-acyloxy-azoxy compounds are formed.

  亚硝基链烷二聚体与酰卤反应，生成含氧氮的取代基为α的α-卤代-氮氧基化合物。在碳酸银的存在下，形成相应的α-酰氧基-乙氧基化合物。
• Oxidation of primary aliphatic amines with sodium perborate
  作者：Walter W Zajac、Michael G Darcy、Amador P Subong、John H Buzby

  DOI：10.1016/s0040-4039(01)89003-1

  日期：1989.1

  A biphasic system of ethyl acetate and water containing sodium perborate, sodium bicarbonate and N,N,N′N′-tetraacetylethylenediamine oxidizes primary aliphatic amines to aliphatic C-nitroso compounds in good to excellent yields.

  包含过硼酸钠，碳酸氢钠和N，N，N'N'-四乙酰基乙二胺的乙酸乙酯和水的双相系统将伯脂肪族胺氧化成脂肪族C-亚硝基化合物的产率高至优异。
• Dimethyldioxirane oxidation of primary amines
  作者：Jack K. Crandall、Thierry Reix

  DOI：10.1021/jo00051a017

  日期：1992.12

  Several primary amines 2 have been oxidized with dimethyldioxirane (1) under a variety of conditions. Mixtures of dimeric nitrosoalkanes 4 and oximes 5 were typically obtained with solutions of the oxidant in excess. In several instances, nitrones 12 were found as byproducts in these reactions. In situ oxidations using oxone in buffered aqueous acetone solution also gave nitrosoalkanes 4 and oximes 3 as important products; in addition, oxaziridines 11 were obtained in significant amounts in biphasic procedures containing methylene chloride. The corresponding nitroalkanes 3 were not formed in major amounts in either oxidation procedure, unless large excesses of oxidant were used. These results are discussed in terms of the several competing processes which occur under the different reaction conditions.