3-((hydroxyethyl)(phenyl)amino)propan-1-ol | 65869-15-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 3-((hydroxyethyl)(phenyl)amino)propan-1-ol
• 英文别名: dl-N-(β-Hydroxyethyl)-N-(β-hydroxypropyl)anilin；3-[N-(2-hydroxy-ethyl)-anilino]-propan-1-ol；3-[N-(2-Hydroxy-aethyl)-anilino]-propan-1-ol；N-(2-Hydroxy-aethyl)-N-(3-hydroxy-propyl)-anilin；(β-Oxy-aethyl)-(γ-oxy-propyl)-anilin；3-[N-(2-hydroxyethyl)anilino]propan-1-ol
• CAS: 65869-15-0
• 化学式: C₁₁H₁₇NO₂
• mdl: MFCD15205190
• 分子量: 195.261
• InChiKey: MLLXTBJHKDAXEQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.454
• 拓扑面积：
  43.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-((hydroxyethyl)(phenyl)amino)propan-1-ol 在 三氯氧磷 作用下， 生成 N-(2-chloro-ethyl)-N-(3-chloro-propyl)-aniline
  参考文献：
  名称：

  201.一些与芳香“氮芥末”有关的化合物。

  摘要：

  DOI：

  10.1039/jr9500000978
• 作为产物：
  描述：

  苯胺 在 氯仿 、 水 作用下， 生成 3-((hydroxyethyl)(phenyl)amino)propan-1-ol
  参考文献：
  名称：

  How Much Is Enough? Perspectives of Care Recipients and Professionals on the Sufficiency of In-Home Care

  摘要：

  研究目的：本研究旨在增加对评估家庭支持护理中评估者角色影响的认识。作者比较了护理接受者和专业人员在家庭护理质量这一广泛概念的一个方面——非正式和正式护理人员提供的护理量的充分性上的看法。设计与方法：通过电话访谈评估老年人的自我报告和基于与老人的家访护士临床报告来评估家庭护理的充分性。护理根据满足功能依赖需求的非正式和正式帮助的充分性进行评估。统计分析比较了老年人和专业人士的评分。结果：专业人士对护理充分性的评分显著低于老年护理接受者的评分。从护理接受者和专业人员的角度来看，护理的充分性显著与老人和护理人员的共同居住情况以及护理人员的健康状况相关。启示：与以往文献一致，评估者角色被发现会影响家庭护理充分性的评估。研究人员和服务提供者应认识到护理接受者和专业评分并不可互换。

  DOI：

  10.1093/geront/41.6.723

文献信息

• Catalytic Formal Hydroamination of Allylic Alcohols Using Manganese PNP‐Pincer Complexes
  作者：Leandro Duarte de Almeida、Florian Bourriquen、Kathrin Junge、Matthias Beller

  DOI：10.1002/adsc.202100081

  日期：2021.9.7

  Several manganese-PNP pincer catalysts for the formal hydroamination of allylic alcohols are presented. The resulting γ-amino alcohols are selectively obtained in high yields applying Mn-1 in a tandem process under mild conditions.

  介绍了几种用于烯丙醇正式加氢胺化的锰-PNP 钳形催化剂。在温和条件下，采用串联工艺中的Mn-1，选择性地以高产率获得了所得的 γ-氨基醇。
• v. Braun; Braunsdorf, Chemische Berichte, 1921, vol. 54, p. 698
  作者：v. Braun、Braunsdorf

  DOI：——

  日期：——
• How Much Is Enough? Perspectives of Care Recipients and Professionals on the Sufficiency of In-Home Care
  作者：Nancy Morrow-Howell、Enola Proctor、Philip Rozario

  DOI：10.1093/geront/41.6.723

  日期：2001.12.1

  Purpose of the Study: This study sought to increase knowledge about the impact of rater role on the assessment of in-home supportive care. The authors compared the perspectives of care recipients and professionals on one aspect of the broad concept of quality of care in home care—the sufficiency of the amount of care provided by informal and formal caregivers. Design and Method: Sufficiency of home care was assessed through concurrent elderly persons' self-report through telephone interview and nurse clinical report based on in-home interviews with the elder. Care was assessed in terms of the sufficiency of the amount of informal and formal assistance received to meet functional dependency needs. Statistical analyses compared the ratings of elder and professional. Results: Professional ratings of the sufficiency of care were significantly lower than those of the elderly care recipients. From the perspective of both care recipients and professionals, sufficiency of care was significantly related to coresidence of elder and caregiver, and to caregiver health. Implications: Consistent with previous literature, rater role was found to influence the assessment of the sufficiency of in-home care. Researchers and providers should recognize that care recipient and professional ratings are not interchangeable.

  研究目的：本研究旨在增加对评估家庭支持护理中评估者角色影响的认识。作者比较了护理接受者和专业人员在家庭护理质量这一广泛概念的一个方面——非正式和正式护理人员提供的护理量的充分性上的看法。设计与方法：通过电话访谈评估老年人的自我报告和基于与老人的家访护士临床报告来评估家庭护理的充分性。护理根据满足功能依赖需求的非正式和正式帮助的充分性进行评估。统计分析比较了老年人和专业人士的评分。结果：专业人士对护理充分性的评分显著低于老年护理接受者的评分。从护理接受者和专业人员的角度来看，护理的充分性显著与老人和护理人员的共同居住情况以及护理人员的健康状况相关。启示：与以往文献一致，评估者角色被发现会影响家庭护理充分性的评估。研究人员和服务提供者应认识到护理接受者和专业评分并不可互换。
• 201. Some compounds related to the aromatic “nitrogen mustards.”
  作者：George A. R. Kon、John J. Roberts

  DOI：10.1039/jr9500000978

  日期：——