3-methyl-3-(2,2,3,3,-tetrafluoropropoxymethyl)oxetane | 879546-71-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环丁烷
• 英文名称: 3-methyl-3-(2,2,3,3,-tetrafluoropropoxymethyl)oxetane
• 英文别名: 3-Methyl-3-[(2,2,3,3-tetrafluoropropoxy)methyl]oxetane；3-methyl-3-(2,2,3,3-tetrafluoropropoxymethyl)oxetane
• CAS: 879546-71-1
• 化学式: C₈H₁₂F₄O₂
• 分子量: 216.176
• InChiKey: AGTRXSARVPSLKO-UHFFFAOYSA-N

物化性质

• 沸点：
  189.2±40.0 °C(Predicted)
• 密度：
  1.203±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  3-溴甲基-3-甲基-1-氧杂环丁烷 、 四氟丙醇 在 四丁基溴化铵 、 potassium hydroxide 作用下， 以 水 为溶剂， 反应 73.0h， 生成 3-methyl-3-(2,2,3,3,-tetrafluoropropoxymethyl)oxetane
  参考文献：
  名称：

  Strongly amphiphilic wetting behavior for polyurethanes with polyoxetane soft blocks having –CF2H terminated side chains

  摘要：

  Two novel polyoxetanes with -CF2CF2H (4F) or -(CF2)(3)CF2H (8F) terminated side chains were synthesized and characterized by H-1 NMR spectroscopy, DSC and GPC. 4F and 8F diols were incorporated in polyurethanes IPDI-BD(40)/4F-8.2 (U-4F-8.2) and IPDI-BD(40)/8F-5.8 (U-8F-5.8), where isophorone diisocyanate (IPDI) and 1,4-butane diol (BD) comprise the hard block (40 wt%) and 4F-8.2 or 8F-5.8 are soft blocks with M-n in kDa. Surface characteristics were evaluated using TM-AFM, XPS and dynamic contact angle (DCA) measurements. In contrast to U-4F-8.2, TM-AFM reveals an interesting phase separated surface morphology for U-8F-5.8 apparently driven by higher F side chain content. A model is proposed to account for contact angle measurements that show reversible, strongly amphiphilic wetting with theta(adv) > 100 degrees and theta(rec) < 40 degrees. Resistance to surface phase separation and related studies suggest the -CF2CF2H moiety is an important candidate for expanding the range of functional groups employed in surface modifiers. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.polymer.2014.03.011

文献信息

• Antimicrobial polymeric compositions
  申请人：Virginia Commonwealth University

  公开号：US10117436B2

  公开（公告）日：2018-11-06

  A compound having the formula: wherein n, y, R1 and R2 are defined herein, and others, methods of making of and using, and compositions made thereby which have an antimicrobial resistance effect are described.

  具有以下式子的化合物 其中 n、y、R1 和 R2 在本文中定义，还介绍了具有抗菌效果的其他成分、制造和使用方法以及由此制成的组合物。
• ANTIMICROBIAL POLYMERIC COMPOSITIONS
  申请人：Wynne Kenneth J.

  公开号：US20130183262A1

  公开（公告）日：2013-07-18

  A compound having the formula: wherein n, y, R 1 and R 2 are defined herein, and others, methods of making of and using, and compositions made thereby which have an antimicrobial resistance effect are described.
• Strongly amphiphilic wetting behavior for polyurethanes with polyoxetane soft blocks having –CF2H terminated side chains
  作者：Pinar Kurt、Asima Chakravorty、Xiaomei Zeng、Kenneth J. Wynne

  DOI：10.1016/j.polymer.2014.03.011

  日期：2014.4

  Two novel polyoxetanes with -CF2CF2H (4F) or -(CF2)(3)CF2H (8F) terminated side chains were synthesized and characterized by H-1 NMR spectroscopy, DSC and GPC. 4F and 8F diols were incorporated in polyurethanes IPDI-BD(40)/4F-8.2 (U-4F-8.2) and IPDI-BD(40)/8F-5.8 (U-8F-5.8), where isophorone diisocyanate (IPDI) and 1,4-butane diol (BD) comprise the hard block (40 wt%) and 4F-8.2 or 8F-5.8 are soft blocks with M-n in kDa. Surface characteristics were evaluated using TM-AFM, XPS and dynamic contact angle (DCA) measurements. In contrast to U-4F-8.2, TM-AFM reveals an interesting phase separated surface morphology for U-8F-5.8 apparently driven by higher F side chain content. A model is proposed to account for contact angle measurements that show reversible, strongly amphiphilic wetting with theta(adv) > 100 degrees and theta(rec) < 40 degrees. Resistance to surface phase separation and related studies suggest the -CF2CF2H moiety is an important candidate for expanding the range of functional groups employed in surface modifiers. (C) 2014 Elsevier Ltd. All rights reserved.