potassium 2-phenylpropanoate | 63073-98-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: potassium 2-phenylpropanoate
• 英文别名: potassium phenylpropionate；Potassium;2-phenylpropanoate
• CAS: 63073-98-3
• 化学式: C₉H₉O₂*K
• 分子量: 188.268
• InChiKey: CIGQWNHYLFZWLG-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.46
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-甲基邻苯二甲酰亚胺 、 potassium 2-phenylpropanoate 以 水 、 丙酮 为溶剂， 反应 2.0h， 生成 、
  参考文献：
  名称：

  Photodecarboxylative benzylations of phthalimides

  摘要：

  Photoadditions of phenylacetates to phthalimides give the corresponding benzylated hydroxyphthalimidines in moderate to high yields of 29-90%. With 2-phenylpropanoate, photoaddition affords a diastereoisomeric mixture in a de of 24% in favour of the like-diastereoisomer. L-3-Phenyl lactate and 2-oxo-3-phenylpropanoate both furnish the benzylated product through subsequent loss of formaldehyde and decarbonylation, respectively. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.08.115

文献信息

• Pharmaceutical composition containing at least a polymer combined with or conjugated to at least a phenylalkylcarboxylic acid salt, conjugate polymers and uses thereof
  申请人：——

  公开号：US20030171333A1

  公开（公告）日：2003-09-11

  The invention concerns a pharmaceutical composition containing at least a polymer associated or conjugated with at least a phenylalkylcarboxylic acid derivative, novel polymers conjugated with at least a phenylalkylcarboxylic acid derivative and their uses in particular in cancer treatment.

  本发明涉及一种药物组成物，该药物组成物至少包含与至少一种苯基烷基羧酸衍生物相关联或共轭的聚合物，以及与至少一种苯基烷基羧酸衍生物共轭的新型聚合物，特别是在癌症治疗中的应用。
• Ink jet printed matter
  申请人：KONICA CORPORATION

  公开号：US20030202082A1

  公开（公告）日：2003-10-30

  A printed mater prepared by jetted ink. The ink is hardened by irradiation of radiation or heat, and the ratio of total thickness of the ink layer to total thickness of the substrate is from 0.40 to 0.05.

  通过喷射油墨制备的印刷材料。油墨通过辐射或加热硬化，油墨层总厚度与基材总厚度之比为 0.40 至 0.05。
• [EN] TIZANIDINE LIQUID PREPARATION AND USE THEREOF<br/>[FR] PRÉPARATION LIQUIDE DE TIZANIDINE ET SON UTILISATION<br/>[ZH] 一种替扎尼定液体制剂及其用途
  申请人：[en]SICHUAN CREDIT PHARMACEUTICAL CO., LTD;[zh]四川科瑞德制药股份有限公司

  公开号：WO2022247609A1

  公开（公告）日：2022-12-01

  一种替扎尼定液体制剂及其在制备治疗肌肉痉挛的药物中的用途，该替扎尼定液体制剂包括活性成分、EDTA二钠及其他药物赋形剂，其中活性成分为替扎尼定或其药学上可接受的盐、溶剂化物、水合物中的一种或多种。
• Photodecarboxylative benzylations of phthalimide in pH 7 buffer: a simple access to 3-arylmethyleneisoindolin-1-ones
  作者：Vincent Belluau、Pierre Noeureuil、Elfrun Ratzke、Aleksei Skvortsov、Sonia Gallagher、Cherri Ann Motti、Michael Oelgemöller

  DOI：10.1016/j.tetlet.2010.07.017

  日期：2010.9

  Photoadditions of phenylacetates to phthalimide in pH 7 buffer solution give the corresponding benzylated-hydroxyphthalimidines in moderate to high yields of up to 94%. In a micro-structured reactor, higher conversions and purities are achieved. With branched phenylacetates, photoaddition affords diastereoisomeric mixtures with low to moderate de values. Subsequent acid-catalyzed dehydration furnishes the corresponding 3-arylmethyleneisoindolin-1-ones in good to excellent yields and with high E-selectivities. Irradiation of the parent 3-phenylmethyleneisoindolin-1-one under oxidative conditions only leads to cis/trans-isomerization. (C) 2010 Elsevier Ltd. All rights reserved.
• COMPOSITION PHARMACEUTIQUE CONTENANT AU MOINS UN POLYMERE ASSOCIE OU CONJUGUE A AU MOINS UN SEL D'UN ACIDE PHENYLALKYLCARBOXYLIQUE, POLYMERES CONJUGUES ET LEURS APPLICATIONS
  申请人：BIODEX

  公开号：EP1289515B1

  公开（公告）日：2004-10-13