n-decylphosphonous acid | 4741-18-8

• 分子结构分类: 有机化合物 - 有机磷化合物 - 二羟基膦
• 英文名称: n-decylphosphonous acid
• 英文别名: n-Decan-phosphonigsaeure；decylphosphonous acid
• CAS: 4741-18-8
• 化学式: C₁₀H₂₃O₂P
• 分子量: 206.265
• InChiKey: PIXOLJPRTSVSFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  13
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  n-decylphosphonous acid 在 4-二甲氨基吡啶 、 sodium periodate 、 N,N'-二环己基碳二亚胺 作用下， 以 四氢呋喃 、 1,4-二氧六环 、 水 为溶剂， 反应 24.0h， 生成 Decyl-phosphonic acid monobenzyl ester
  参考文献：
  名称：

  Phosphonate-containing analogs of cholesteryl ester as novel inhibitors of cholesteryl ester transfer protein

  摘要：

  A series of phosphorus-containing analogs of cholesteryl ester have been synthesized as potential inhibitors of cholesteryl ester transfer protein (CETP). The most potent inhibitor, phosphonate 7, represents a novel inhibitor of CETP. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0960-894x(96)00350-2
• 作为产物：
  描述：

  正癸烯 在 sodium hypophosphite 、 偶氮二异丁腈 、 硫酸 作用下， 以 乙醇 为溶剂， 反应 12.0h， 生成 n-decylphosphonous acid
  参考文献：
  名称：

  Phosphonate-containing analogs of cholesteryl ester as novel inhibitors of cholesteryl ester transfer protein

  摘要：

  A series of phosphorus-containing analogs of cholesteryl ester have been synthesized as potential inhibitors of cholesteryl ester transfer protein (CETP). The most potent inhibitor, phosphonate 7, represents a novel inhibitor of CETP. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0960-894x(96)00350-2

文献信息

• Process for preparing phosphonic acids
  申请人：E. R. Squibb & Sons, Inc.

  公开号：US04670193A1

  公开（公告）日：1987-06-02

  A process for preparing phosphonic acids of the structure ##STR1## wherein R.sub.1 is lower alkyl, aryl, cycloalkyl or arylalkyl, and R.sub.2 is H, benzyl or ##STR2## by oxidizing the corresponding phosphonous acid ##STR3## employing as the oxidizing agent potassium permanganate or sodium periodate.

  一种制备磷酸的过程，其结构为##STR1##其中R.sub.1是低烷基，芳基，环烷基或芳基烷基，R.sub.2是H，苄基或##STR2##，通过使用高锰酸钾或过碘酸钠作为氧化剂氧化相应的膦酸##STR3##。
• KARANEWSKY, DONALD S.;BADIA, MICHAEL C.;CUSHMAN, DAVID W.;DEFORREST, JACK+, J. MED. CHEM., 31,(1988) N 1, 204-212
  作者：KARANEWSKY, DONALD S.、BADIA, MICHAEL C.、CUSHMAN, DAVID W.、DEFORREST, JACK+

  DOI：——

  日期：——
• COMPOSITION
  申请人：FUJIFILM Corporation

  公开号：US20220045283A1

  公开（公告）日：2022-02-10

  An object of the present invention is to provide a composition capable of manufacturing an organic thin film transistor having excellent carrier mobility even under low temperature conditions. The composition of the present invention contains a compound represented by Formula (1) and an alcohol represented by Formula (S1).
• COMPOUND AND METHOD FOR PRODUCING COMPOUND
  申请人：FUJIFILM Corporation

  公开号：US20220389016A1

  公开（公告）日：2022-12-08

  The present invention provides an intermediate compound for easily producing a compound having an azaperylene skeleton. Another object of the present invention is to provide a method for easily producing a compound having an azaperylene skeleton. The compound of the present invention is a compound represented by Formula (I), or a compound represented by Formula (II).
• US4670193A
  申请人：——

  公开号：US4670193A

  公开（公告）日：1987-06-02