6-(3-aminophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine | 1044656-17-8

分子结构分类

有机化合物 - 有机杂环化合物 - 咪唑并吡嗪类

中文名称

——

中文别名

——

英文名称

6-(3-aminophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine

英文别名

[6-(3-amino-phenyl)-imidazo[1,2-a]pyrazin-8-yl]-pyridin-4-ylmethyl-amine

6-(3-aminophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine化学式

CAS

1044656-17-8

化学式

C₁₈H₁₆N₆

mdl

——

分子量

316.365

InChiKey

WOAGVNUSBTUWMV-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

物化性质

密度：

1.34±0.1 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

2.4
重原子数：

24
可旋转键数：

4
环数：

4.0
sp3杂化的碳原子比例：

0.06
拓扑面积：

81.1
氢给体数：

2
氢受体数：

5

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	6-bromo-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine	1202810-48-7	C₁₂H₁₀BrN₅	304.149

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	1-Phenyl-3-[3-[8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl]phenyl]urea	1202810-55-6	C₂₅H₂₁N₇O	435.488
——	1-(3-(8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-p-tolylurea	1202810-74-9	C₂₆H₂₃N₇O	449.515
——	1-(4-Bromophenyl)-3-[3-[8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl]phenyl]urea	1202810-73-8	C₂₅H₂₀BrN₇O	514.384
——	1-(4-chloro-phenyl)-3-(3-{8-[(pyridin-4-ylmethyl)-amino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-urea	673857-15-3	C₂₅H₂₀ClN₇O	469.933
——	1-(4-Fluorophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-72-7	C₂₅H₂₀FN₇O	453.479
——	1-(4-Ethylphenyl)-3-[3-[8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl]phenyl]urea	1202810-71-6	C₂₇H₂₅N₇O	463.542
——	1-(3-{8-[(pyridin-4-yl-methyl)-amino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-3-m-tolyl-urea	847024-25-3	C₂₆H₂₃N₇O	449.515
——	1-(4-Methoxyphenyl)-3-[3-[8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl]phenyl]urea	1202810-75-0	C₂₆H₂₃N₇O₂	465.514
——	1-(3-chloro-phenyl)-3-(3-{8-[(pyridin-4-yl-methyl)-amino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-urea	847024-26-4	C₂₅H₂₀ClN₇O	469.933
——	1-(3-Fluorophenyl)-3-[3-[8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl]phenyl]urea	1202810-64-7	C₂₅H₂₀FN₇O	453.479
——	1-(3-Bromophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-66-9	C₂₅H₂₀BrN₇O	514.384
——	1-(2-Methylphenyl)-3-[3-[8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl]phenyl]urea	1202810-59-0	C₂₆H₂₃N₇O	449.515
——	1-[3-[8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]urea	1202810-76-1	C₂₆H₂₀F₃N₇O	503.486
——	1-(3,5-Dichlorophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-83-0	C₂₅H₁₉Cl₂N₇O	504.378
——	1-(2-Bromophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-58-9	C₂₅H₂₀BrN₇O	514.384
——	1-(3-Cyanophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-69-2	C₂₆H₂₀N₈O	460.498
——	1-(2-Chlorophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-57-8	C₂₅H₂₀ClN₇O	469.933
——	1-(3,4-Dichlorophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-82-9	C₂₅H₁₉Cl₂N₇O	504.378
——	1-(3-Methoxyphenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-67-0	C₂₆H₂₃N₇O₂	465.514
——	1-(2,6-Dichlorophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-84-1	C₂₅H₁₉Cl₂N₇O	504.378
——	1-(3-(Methylthio)phenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-68-1	C₂₆H₂₃N₇OS	481.581
——	1-(2,4-Dichlorophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-81-8	C₂₅H₁₉Cl₂N₇O	504.378
——	1-(3-Phenoxyphenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-70-5	C₃₁H₂₅N₇O₂	527.585
——	1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea	673857-16-4	C₂₆H₂₀F₃N₇O	503.486
——	1-(2,5-Dimethylphenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-78-3	C₂₇H₂₅N₇O	463.542
——	1-(2,5-Dichlorophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-79-4	C₂₅H₁₉Cl₂N₇O	504.378
——	1-(2-Methoxyphenyl)-3-[3-[8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl]phenyl]urea	1202810-60-3	C₂₆H₂₃N₇O₂	465.514
——	1-(2-Methylsulfanylphenyl)-3-[3-[8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl]phenyl]urea	1202810-62-5	C₂₆H₂₃N₇OS	481.581
——	1-(2,3-Dichlorophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-80-7	C₂₅H₁₉Cl₂N₇O	504.378
——	1-(5-Chloro-2-methylphenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-85-2	C₂₆H₂₂ClN₇O	483.96
——	1-[3-[8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-[2-(trifluoromethyl)phenyl]urea	1202810-61-4	C₂₆H₂₀F₃N₇O	503.486
——	1-(3-{8-[(pyridin-4-yl-methyl)-amino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-3-(2,4,5-trichloro-phenyl)-urea	847024-40-2	C₂₅H₁₈Cl₃N₇O	538.823
——	1-(3-(8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(4-(trifluoromethyl)benzyl)urea	1202810-97-6	C₂₇H₂₂F₃N₇O	517.513
——	1-(4-methyl-3-trifluoromethyl-phenyl)-3-(3-{8-[(pyridin-4-yl-methyl)-amino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-urea	847024-27-5	C₂₇H₂₂F₃N₇O	517.513
——	1-(2-Methoxy-5-methylphenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-87-4	C₂₇H₂₅N₇O₂	479.541
——	1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea	1202810-90-9	C₂₆H₁₉ClF₃N₇O	537.931
——	1-(5-chloro-2-methoxy-phenyl)-3-(3-{8-[(pyridin-4-yl-methyl)-amino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-urea	847024-28-6	C₂₆H₂₂ClN₇O₂	499.959
——	1-(2-chloro-5-trifluoromethyl-phenyl)-3-(3-{8-[(pyridin-4-yl-methyl)-amino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-urea	847024-29-7	C₂₆H₁₉ClF₃N₇O	537.931
——	1-(2-fluoro-5-trifluoromethyl-phenyl)-3-(3-{8-[(-pyridin-4-yl-methyl)-amino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-urea	847024-35-5	C₂₆H₁₉F₄N₇O	521.477
——	1-(4-fluoro-3-trifluoromethyl-phenyl)-3-(3-{8-[(pyridin-4-yl-methyl)-amino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-urea	847024-50-4	C₂₆H₁₉F₄N₇O	521.477